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PubMed for id: 1890268227

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Page 1
Fusion crystallization reveals the behavior of both the 1TEL crystallization chaperone and the TNK1 UBA domain.
Nawarathnage S, Tseng YJ, Soleimani S, Smith T, Pedroza Romo MJ, Abiodun WO, Egbert CM, Madhusanka D, Bunn D, Woods B, Tsubaki E, Stewart C, Brown S, Doukov T, Andersen JL, Moody JD. Nawarathnage S, et al. Structure. 2023 Dec 7;31(12):1589-1603.e6. doi: 10.1016/j.str.2023.09.001. Epub 2023 Sep 29. Structure. 2023. PMID: 37776857 Free article.
A central chaperone-like role for 14-3-3 proteins in human cells.
Segal D, Maier S, Mastromarco GJ, Qian WW, Nabeel-Shah S, Lee H, Moore G, Lacoste J, Larsen B, Lin ZY, Selvabaskaran A, Liu K, Smibert C, Zhang Z, Greenblatt J, Peng J, Lee HO, Gingras AC, Taipale M. Segal D, et al. Mol Cell. 2023 Mar 16;83(6):974-993.e15. doi: 10.1016/j.molcel.2023.02.018. Mol Cell. 2023. PMID: 36931259 Free article.
TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth.
Chan TY, Egbert CM, Maxson JE, Siddiqui A, Larsen LJ, Kohler K, Balasooriya ER, Pennington KL, Tsang TM, Frey M, Soderblom EJ, Geng H, Müschen M, Forostyan TV, Free S, Mercenne G, Banks CJ, Valdoz J, Whatcott CJ, Foulks JM, Bearss DJ, O'Hare T, Huang DCS, Christensen KA, Moody J, Warner SL, Tyner JW, Andersen JL. Chan TY, et al. Nat Commun. 2021 Sep 9;12(1):5337. doi: 10.1038/s41467-021-25622-3. Nat Commun. 2021. PMID: 34504101 Free PMC article.