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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
---|---|
2010 | 1 |
2011 | 2 |
2012 | 1 |
2013 | 1 |
2024 | 0 |
PubMed (MeSH Keyword) for id: 23634407
4 results
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A phase I, dose-escalation study of the Eg5-inhibitor EMD 534085 in patients with advanced solid tumors or lymphoma.
Invest New Drugs. 2013 Dec;31(6):1530-8. doi: 10.1007/s10637-013-0026-9.
Invest New Drugs. 2013.
PMID: 24077982
Clinical Trial.
Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 induction.
Orth JD, Loewer A, Lahav G, Mitchison TJ.
Orth JD, et al.
Mol Biol Cell. 2012 Feb;23(4):567-76. doi: 10.1091/mbc.E11-09-0781. Epub 2011 Dec 14.
Mol Biol Cell. 2012.
PMID: 22171325
Free PMC article.
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Rapid induction of apoptosis during Kinesin-5 inhibitor-induced mitotic arrest in HL60 cells.
Tang Y, Orth JD, Xie T, Mitchison TJ.
Tang Y, et al.
Cancer Lett. 2011 Nov 1;310(1):15-24. doi: 10.1016/j.canlet.2011.05.024. Epub 2011 Jun 24.
Cancer Lett. 2011.
PMID: 21782324
Free PMC article.
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The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5.
Schiemann K, Finsinger D, Zenke F, Amendt C, Knöchel T, Bruge D, Buchstaller HP, Emde U, Stähle W, Anzali S.
Schiemann K, et al.
Bioorg Med Chem Lett. 2010 Mar 1;20(5):1491-5. doi: 10.1016/j.bmcl.2010.01.110. Epub 2010 Jan 25.
Bioorg Med Chem Lett. 2010.
PMID: 20149654
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