PubMed (MeSH Keyword) for id: 4578

Year	Number of Results
1990	2
1991	4
1992	5
1993	15
1994	14
1995	13
1996	23
1997	16
1998	16
1999	21
2000	24
2001	17
2002	12
2003	17
2004	10
2005	12
2006	14
2007	13
2008	9
2009	13
2010	8
2011	5
2012	8
2013	7
2014	11
2015	2
2016	8
2017	6
2018	7
2019	4
2020	3
2021	3
2022	1
2024	0

1

Acridine-O⁶-benzylguanine hybrids: Synthesis, DNA binding, MGMT inhibition and antiproliferative activity.

Franco Pinto J, Fillion A, Duchambon P, Bombard S, Granzhan A. Franco Pinto J, et al. Eur J Med Chem. 2022 Jan 5;227:113909. doi: 10.1016/j.ejmech.2021.113909. Epub 2021 Oct 9. Eur J Med Chem. 2022. PMID: 34731767 Free article.

2

The O6-methyguanine-DNA methyltransferase inhibitor O6-benzylguanine enhanced activity of temozolomide + irinotecan against models of high-risk neuroblastoma.

Hindle A, Koneru B, Makena MR, Lopez-Barcons L, Chen WH, Nguyen TH, Reynolds CP. Hindle A, et al. Anticancer Drugs. 2021 Mar 1;32(3):233-247. doi: 10.1097/CAD.0000000000001020. Anticancer Drugs. 2021. PMID: 33323683 Free PMC article.

3

Site-Directed Mutagenesis at the Molybdenum Pterin Cofactor Site of the Human Aldehyde Oxidase: Interrogating the Kinetic Differences Between Human and Cynomolgus Monkey.

Abbasi A, Joswig-Jones CA, Jones JP. Abbasi A, et al. Drug Metab Dispos. 2020 Dec;48(12):1364-1371. doi: 10.1124/dmd.120.000187. Epub 2020 Oct 5. Drug Metab Dispos. 2020. PMID: 33020066 Free PMC article.

4

MGMT-inhibitor in combination with TGF-βRI inhibitor or CDK 4/6 inhibitor increases temozolomide sensitivity in temozolomide-resistant glioblastoma cells.

Das A, Henderson FC Jr, Alshareef M, Porto GBF, Kanginakudru I, Infinger LK, Vandergrift WA 3rd, Lindhorst SM, Varma AK, Patel SJ, Cachia D. Das A, et al. Clin Transl Oncol. 2021 Mar;23(3):612-619. doi: 10.1007/s12094-020-02456-x. Epub 2020 Jul 25. Clin Transl Oncol. 2021. PMID: 32710211

5

An LC-MS/MS method for determination of O⁶ -benzylguanine and its metabolite O⁶ -benzyl-8-oxoguanine in human plasma.

Mannem C, Xu Y. Mannem C, et al. Biomed Chromatogr. 2020 Feb;34(2):e4750. doi: 10.1002/bmc.4750. Epub 2020 Jan 6. Biomed Chromatogr. 2020. PMID: 31743472

6

Site-Specific Immobilization of β₂-AR Using O⁶-Benzylguanine Derivative-Functionalized Supporter for High-Throughput Receptor-Targeting Lead Discovery.

Wang J, Wang Y, Liu J, Li Q, Yin G, Zhang Y, Xiao C, Fan T, Zhao X, Zheng X. Wang J, et al. Anal Chem. 2019 Jun 4;91(11):7385-7393. doi: 10.1021/acs.analchem.9b01268. Epub 2019 May 22. Anal Chem. 2019. PMID: 31070886

7

Methylation Tolerance-Based Functional Assay to Assess Variants of Unknown Significance in the MLH1 and MSH2 Genes and Identify Patients With Lynch Syndrome.

Bouvet D, Bodo S, Munier A, Guillerm E, Bertrand R, Colas C, Duval A, Coulet F, Muleris M. Bouvet D, et al. Gastroenterology. 2019 Aug;157(2):421-431. doi: 10.1053/j.gastro.2019.03.071. Epub 2019 Apr 15. Gastroenterology. 2019. PMID: 30998989

8

Beyond O⁶-Benzylguanine: O⁶-(5-Pyridylmethyl)guanine as a Substrate for the Self-Labeling Enzyme SNAP-Tag.

Macias-Contreras M, He H, Zhu L. Macias-Contreras M, et al. Bioconjug Chem. 2018 Dec 19;29(12):4104-4109. doi: 10.1021/acs.bioconjchem.8b00703. Epub 2018 Nov 20. Bioconjug Chem. 2018. PMID: 30411875

9

Evaluation of Carbazeran 4-Oxidation and O ⁶-Benzylguanine 8-Oxidation as Catalytic Markers of Human Aldehyde Oxidase: Impact of Cytosolic Contamination of Liver Microsomes.

Xie J, Saburulla NF, Chen S, Wong SY, Yap ZP, Zhang LH, Lau AJ. Xie J, et al. Drug Metab Dispos. 2019 Jan;47(1):26-37. doi: 10.1124/dmd.118.082099. Epub 2018 Oct 18. Drug Metab Dispos. 2019. PMID: 30337443

10

Study of aldehyde oxidase by micellar electrokinetic chromatography separation of O⁶ -benzylguanine and 8-oxo-O⁶ -benzylguanine.

Huang S, Adams E, Van Schepdael A. Huang S, et al. Electrophoresis. 2019 Jan;40(2):330-335. doi: 10.1002/elps.201800279. Epub 2018 Sep 30. Electrophoresis. 2019. PMID: 30221782

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