PubMed (cited) for id: 600993

Year	Number of Results
1983	1
1995	1
1996	6
1997	1
1998	9
1999	1
2000	1
2002	8
2003	1
2004	2
2005	1
2006	4
2007	1
2008	1
2009	1
2010	1
2011	3
2012	3
2013	2
2015	1
2016	2
2017	2
2018	1
2024	0

1

Smad4 deficiency impairs chondrocyte hypertrophy via the Runx2 transcription factor in mouse skeletal development.

Yan J, Li J, Hu J, Zhang L, Wei C, Sultana N, Cai X, Zhang W, Cai CL. Yan J, et al. J Biol Chem. 2018 Jun 15;293(24):9162-9175. doi: 10.1074/jbc.RA118.001825. Epub 2018 May 7. J Biol Chem. 2018. PMID: 29735531 Free PMC article.

2

Reversing SKI-SMAD4-mediated suppression is essential for T_H17 cell differentiation.

Zhang S, Takaku M, Zou L, Gu AD, Chou WC, Zhang G, Wu B, Kong Q, Thomas SY, Serody JS, Chen X, Xu X, Wade PA, Cook DN, Ting JPY, Wan YY. Zhang S, et al. Nature. 2017 Nov 2;551(7678):105-109. doi: 10.1038/nature24283. Epub 2017 Oct 25. Nature. 2017. PMID: 29072299 Free PMC article.

3

Tumor suppressor bromodomain-containing protein 7 cooperates with Smads to promote transforming growth factor-β responses.

Liu T, Zhao M, Liu J, He Z, Zhang Y, You H, Huang J, Lin X, Feng XH. Liu T, et al. Oncogene. 2017 Jan 19;36(3):362-372. doi: 10.1038/onc.2016.204. Epub 2016 Jun 6. Oncogene. 2017. PMID: 27270427 Free PMC article.

4

Smad4 Deficiency in Smooth Muscle Cells Initiates the Formation of Aortic Aneurysm.

Zhang P, Hou S, Chen J, Zhang J, Lin F, Ju R, Cheng X, Ma X, Song Y, Zhang Y, Zhu M, Du J, Lan Y, Yang X. Zhang P, et al. Circ Res. 2016 Feb 5;118(3):388-99. doi: 10.1161/CIRCRESAHA.115.308040. Epub 2015 Dec 23. Circ Res. 2016. PMID: 26699655

5

BMP signaling controls muscle mass.

Sartori R, Schirwis E, Blaauw B, Bortolanza S, Zhao J, Enzo E, Stantzou A, Mouisel E, Toniolo L, Ferry A, Stricker S, Goldberg AL, Dupont S, Piccolo S, Amthor H, Sandri M. Sartori R, et al. Nat Genet. 2013 Nov;45(11):1309-18. doi: 10.1038/ng.2772. Epub 2013 Sep 29. Nat Genet. 2013. PMID: 24076600

6

COUP-TFII inhibits TGF-β-induced growth barrier to promote prostate tumorigenesis.

Qin J, Wu SP, Creighton CJ, Dai F, Xie X, Cheng CM, Frolov A, Ayala G, Lin X, Feng XH, Ittmann MM, Tsai SJ, Tsai MJ, Tsai SY. Qin J, et al. Nature. 2013 Jan 10;493(7431):236-40. doi: 10.1038/nature11674. Epub 2012 Nov 28. Nature. 2013. PMID: 23201680 Free PMC article.

7

Mutations of SMAD4 account for both LAPS and Myhre syndromes.

Lindor NM, Gunawardena SR, Thibodeau SN. Lindor NM, et al. Am J Med Genet A. 2012 Jun;158A(6):1520-1. doi: 10.1002/ajmg.a.35374. Epub 2012 May 14. Am J Med Genet A. 2012. PMID: 22585601 No abstract available.

8

A restricted spectrum of mutations in the SMAD4 tumor-suppressor gene underlies Myhre syndrome.

Caputo V, Cianetti L, Niceta M, Carta C, Ciolfi A, Bocchinfuso G, Carrani E, Dentici ML, Biamino E, Belligni E, Garavelli L, Boccone L, Melis D, Andria G, Gelb BD, Stella L, Silengo M, Dallapiccola B, Tartaglia M. Caputo V, et al. Am J Hum Genet. 2012 Jan 13;90(1):161-9. doi: 10.1016/j.ajhg.2011.12.011. Am J Hum Genet. 2012. PMID: 22243968 Free PMC article.

9

Mutations at a single codon in Mad homology 2 domain of SMAD4 cause Myhre syndrome.

Le Goff C, Mahaut C, Abhyankar A, Le Goff W, Serre V, Afenjar A, Destrée A, di Rocco M, Héron D, Jacquemont S, Marlin S, Simon M, Tolmie J, Verloes A, Casanova JL, Munnich A, Cormier-Daire V. Le Goff C, et al. Nat Genet. 2011 Dec 11;44(1):85-8. doi: 10.1038/ng.1016. Nat Genet. 2011. PMID: 22158539

10

SMAD4 mutation segregating in a family with juvenile polyposis, aortopathy, and mitral valve dysfunction.

Andrabi S, Bekheirnia MR, Robbins-Furman P, Lewis RA, Prior TW, Potocki L. Andrabi S, et al. Am J Med Genet A. 2011 May;155A(5):1165-9. doi: 10.1002/ajmg.a.33968. Epub 2011 Apr 4. Am J Med Genet A. 2011. PMID: 21465659

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