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Page 1
Sex-hormone-binding globulin.
Anderson DC. Anderson DC. Clin Endocrinol (Oxf). 1974 Jan;3(1):69-96. doi: 10.1111/j.1365-2265.1974.tb03298.x. Clin Endocrinol (Oxf). 1974. PMID: 4134992 Review.
Steroids are predominately bound to plasma proteins and only unbound steroids enter the cells. Sex-hormone-binding globulin (SHBG) binds to both the main circulating steroid T and E2 but changes in SHBG concentrations exert significant results. ...These disturbances …
Steroids are predominately bound to plasma proteins and only unbound steroids enter the cells. Sex-hormone-binding globulin (SHBG) bi …
Plasma steroid-binding proteins: primary gatekeepers of steroid hormone action.
Hammond GL. Hammond GL. J Endocrinol. 2016 Jul;230(1):R13-25. doi: 10.1530/JOE-16-0070. Epub 2016 Apr 25. J Endocrinol. 2016. PMID: 27113851 Free PMC article. Review.
Biologically active steroids are transported in the blood by albumin, sex hormone-binding globulin (SHBG), and corticosteroid-binding globulin (CBG). ...Understanding how the unique structures of SHBG and CBG determine their specialized functions, how changes …
Biologically active steroids are transported in the blood by albumin, sex hormone-binding globulin (SHBG), and corticosteroid- …
MANAGEMENT OF ENDOCRINE DISEASE Hyperandrogenic states in women: pitfalls in laboratory diagnosis.
Pugeat M, Plotton I, de la Perrière AB, Raverot G, Déchaud H, Raverot V. Pugeat M, et al. Eur J Endocrinol. 2018 Apr;178(4):R141-R154. doi: 10.1530/EJE-17-0776. Epub 2018 Feb 16. Eur J Endocrinol. 2018. PMID: 29453202 Review.
Measuring total testosterone level is the first-line approach in assessing androgen excess in women. ...In general, laboratories using direct testosterone immunoassay and mass spectrometry need to operate within a quality framework and be actively engaged in external quali …
Measuring total testosterone level is the first-line approach in assessing androgen excess in women. ...In general, laboratories usin …
Thyroid hormone receptors and reproduction.
Dittrich R, Beckmann MW, Oppelt PG, Hoffmann I, Lotz L, Kuwert T, Mueller A. Dittrich R, et al. J Reprod Immunol. 2011 Jun;90(1):58-66. doi: 10.1016/j.jri.2011.02.009. Epub 2011 Jun 8. J Reprod Immunol. 2011. PMID: 21641659 Review.
Hyperthyroidism and hypothyroidism cause changes in sex hormone-binding globulin (SHBG), prolactin, gonadotropin-releasing hormone, and sex steroid serum levels. ...Adequate levels of circulating thyroid hormones are of primary importance for normal re …
Hyperthyroidism and hypothyroidism cause changes in sex hormone-binding globulin (SHBG), prolactin, gonadotropin-releasing hormone, a …
Reproductive endocrinology of adolescent polycystic ovary syndrome.
Shayya R, Chang RJ. Shayya R, et al. BJOG. 2010 Jan;117(2):150-5. doi: 10.1111/j.1471-0528.2009.02421.x. BJOG. 2010. PMID: 20002395 Review.
Recognising adolescents at risk for PCOS and taking the appropriate steps to reduce circulating androgen levels is critical in reducing the clinical symptomatology of this disorder, and the development of adulthood infertility, diabetes, and metabolic syndrome in pa …
Recognising adolescents at risk for PCOS and taking the appropriate steps to reduce circulating androgen levels is critical in …
Biomarkers of alcohol consumption and related liver disease.
Niemelä O, Alatalo P. Niemelä O, et al. Scand J Clin Lab Invest. 2010 Sep;70(5):305-12. doi: 10.3109/00365513.2010.486442. Scand J Clin Lab Invest. 2010. PMID: 20470213 Review.
Abstract Alcohol abuse is a major cause of abnormal liver function throughout the world. While measurements of liver enzyme activities (GGT, ALT, AST) are important screening tools for detecting liver disease, due to lack of ethanol-specificity and inconsistencies regardin …
Abstract Alcohol abuse is a major cause of abnormal liver function throughout the world. While measurements of liver enzyme activitie …
Clinical utility of sex hormone-binding globulin measurement.
Pugeat M, Crave JC, Tourniaire J, Forest MG. Pugeat M, et al. Horm Res. 1996;45(3-5):148-55. doi: 10.1159/000184778. Horm Res. 1996. PMID: 8964574 Review.
The high-affinity binding of the sex hormone-binding globulin (SHBG) for testosterone and to a lesser extent for estradiol influences the circulating levels of these sex steroid hormones, their biodisposal to target cells as well as their mutual balance. ...I …
The high-affinity binding of the sex hormone-binding globulin (SHBG) for testosterone and to a lesser extent for estradiol influences …
Norgestimate. From the laboratory to three clinical indications.
Henzl MR. Henzl MR. J Reprod Med. 2001 Jul;46(7):647-61. J Reprod Med. 2001. PMID: 11499185 Review.
NGM has a low androgenic impact and does not interfere with the positive metabolic actions of estrogens, notably the estrogen-induced increase in high-density lipoprotein levels. OCs with NGM and EE increase the serum concentration of sex hormone binding globulin th …
NGM has a low androgenic impact and does not interfere with the positive metabolic actions of estrogens, notably the estrogen-induced increa …
Effect of progestins on IGF-I serum level in estrogen-treated postmenopausal women.
Campagnoli C, Biglia N, Cantamessa C, Di Sario MM, Lesca L. Campagnoli C, et al. Zentralbl Gynakol. 1997;119 Suppl 2:7-11. Zentralbl Gynakol. 1997. PMID: 9361392 Review.
Insulin-like growth factor I (IGF-I) has a role in the whole-body anabolism and promotes both normal and abnormal cell growth in several tissues. Although IGF-I is also synthesized locally at numerous other sites, the liver does constitute the major site of its synthesis, …
Insulin-like growth factor I (IGF-I) has a role in the whole-body anabolism and promotes both normal and abnormal cell growth in seve …