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Membrane proteins implicated in long-chain fatty acid uptake by mammalian cells: CD36, FATP and FABPm.
Abumrad N, Coburn C, Ibrahimi A. Abumrad N, et al. Biochim Biophys Acta. 1999 Oct 18;1441(1):4-13. doi: 10.1016/s1388-1981(99)00137-7. Biochim Biophys Acta. 1999. PMID: 10526223 Review.
Long-chain fatty acids can transfer passively across mammalian cell membranes. ...A simple diffusion process becomes significant at high molar ratios of fatty acid to albumin as the concentration of free fatty acid in solution is i …
Long-chain fatty acids can transfer passively across mammalian cell membranes. ...A simple diffusion process becomes significa …
Ileal bile acid transporter inhibition as an anticholestatic therapeutic target in biliary atresia and other cholestatic disorders.
Karpen SJ, Kelly D, Mack C, Stein P. Karpen SJ, et al. Hepatol Int. 2020 Sep;14(5):677-689. doi: 10.1007/s12072-020-10070-w. Epub 2020 Jul 11. Hepatol Int. 2020. PMID: 32653991 Review.
Improving cholestasis via interruption of the enterohepatic circulation of bile acids may directly attenuate hepatic bile acid retention and reduce the risk of early organ failure. ...This review explores the novel therapeutic concept of inhibiting the sole i …
Improving cholestasis via interruption of the enterohepatic circulation of bile acids may directly attenuate hepatic bile a …