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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1983 1
1984 1
1985 1
1988 1
1989 1
1990 1
1999 1
2001 1
2002 1
2004 2
2005 1
2006 4
2007 3
2008 1
2009 2
2010 2
2011 4
2012 3
2013 4
2014 1
2015 4
2016 6
2017 2
2018 1
2019 2
2020 5
2021 3
2022 3
2023 6
2024 2

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62 results

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Page 1
Idiopathic pulmonary fibrosis.
King TE Jr, Pardo A, Selman M. King TE Jr, et al. Lancet. 2011 Dec 3;378(9807):1949-61. doi: 10.1016/S0140-6736(11)60052-4. Epub 2011 Jun 28. Lancet. 2011. PMID: 21719092 Review.
This disease was once thought to be a chronic inflammatory process, but current evidence indicates that the fibrotic response is driven by abnormally activated alveolar epithelial cells (AECs). These cells produce mediators that induce the forma …
This disease was once thought to be a chronic inflammatory process, but current evidence indicates that the fibrotic response is driven by …
Cellular metabolomics of pulmonary fibrosis, from amino acids to lipids.
Roque W, Romero F. Roque W, et al. Am J Physiol Cell Physiol. 2021 May 1;320(5):C689-C695. doi: 10.1152/ajpcell.00586.2020. Epub 2021 Jan 20. Am J Physiol Cell Physiol. 2021. PMID: 33471621 Free PMC article. Review.
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease of unknown etiology with limited treatment options. It is characterized by repetitive injury to alveolar epithelial cells and aberrant activation of numerous signaling pathways. Rec …
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease of unknown etiology with limited treatment options. It is char …
Common Pathogenic Mechanisms Between Idiopathic Pulmonary Fibrosis and Lung Cancer.
Tzouvelekis A, Gomatou G, Bouros E, Trigidou R, Tzilas V, Bouros D. Tzouvelekis A, et al. Chest. 2019 Aug;156(2):383-391. doi: 10.1016/j.chest.2019.04.114. Epub 2019 May 22. Chest. 2019. PMID: 31125557 Review.
Aberrant epigenetic regulation due to methylation, histone modifications, and mainly deregulation of common noncoding RNAs represents a possible pathogenic link between the two disease paradigms. Genetic and epigenetic alterations lead to abnormal activation of common tran …
Aberrant epigenetic regulation due to methylation, histone modifications, and mainly deregulation of common noncoding RNAs represents a poss …
Monocytes and macrophages: emerging mechanisms and novel therapeutic targets in pulmonary fibrosis.
Perrot CY, Karampitsakos T, Herazo-Maya JD. Perrot CY, et al. Am J Physiol Cell Physiol. 2023 Oct 1;325(4):C1046-C1057. doi: 10.1152/ajpcell.00302.2023. Epub 2023 Sep 11. Am J Physiol Cell Physiol. 2023. PMID: 37694283 Free PMC article. Review.
Pulmonary fibrosis results from a plethora of abnormal pathogenetic events. In idiopathic pulmonary fibrosis (IPF), inhalational, environmental, or occupational exposures in genetically and epigenetically predisposed individuals trigger recurrent cycles of alveolar …
Pulmonary fibrosis results from a plethora of abnormal pathogenetic events. In idiopathic pulmonary fibrosis (IPF), inhalational, env …
Regulation of alveolar type 2 stem/progenitor cells in lung injury and regeneration.
Wu A, Song H. Wu A, et al. Acta Biochim Biophys Sin (Shanghai). 2020 Jul 10;52(7):716-722. doi: 10.1093/abbs/gmaa052. Acta Biochim Biophys Sin (Shanghai). 2020. PMID: 32445469 Free article. Review.
The renewal of lung epithelial cells is normally slow unless the lung is injured. The resident epithelial stem cells rapidly proliferate and differentiate to maintain lung structure and function when the lung is damaged. The alveolar epithelium …
The renewal of lung epithelial cells is normally slow unless the lung is injured. The resident epithelial stem cells …
Targeting Histone Deacetylases in Idiopathic Pulmonary Fibrosis: A Future Therapeutic Option.
Korfei M, Mahavadi P, Guenther A. Korfei M, et al. Cells. 2022 May 12;11(10):1626. doi: 10.3390/cells11101626. Cells. 2022. PMID: 35626663 Free PMC article. Review.
Increased HDAC expression is associated with cell proliferation, cell growth and anti-apoptosis and is, thus, a salient feature of many cancers. In IPF, induction and abnormal upregulation of Class I and Class II HDAC enzymes in myofibroblast foci, as well as aberra …
Increased HDAC expression is associated with cell proliferation, cell growth and anti-apoptosis and is, thus, a salient feature of many canc …
The Epithelial-Immune Crosstalk in Pulmonary Fibrosis.
Planté-Bordeneuve T, Pilette C, Froidure A. Planté-Bordeneuve T, et al. Front Immunol. 2021 May 19;12:631235. doi: 10.3389/fimmu.2021.631235. eCollection 2021. Front Immunol. 2021. PMID: 34093523 Free PMC article. Review.
Although the distal lung epithelium and local immunity have been implicated in the pathogenesis and disease course of idiopathic pulmonary fibrosis (IPF), consequences of their abnormal interplay remain less well known. Recent data suggests a two-way process, as illustrate …
Although the distal lung epithelium and local immunity have been implicated in the pathogenesis and disease course of idiopathic pulmonary f …
Drug-induced pulmonary fibrosis.
Adamson IY. Adamson IY. Environ Health Perspect. 1984 Apr;55:25-36. doi: 10.1289/ehp.845525. Environ Health Perspect. 1984. PMID: 6203733 Free PMC article. Review.
Using bleomycin toxicity as an example, it has been shown that, after IV injection, the selective site of lung injury is the vascular endothelium; this is followed by the accumulation of interstitial edema and later by necrosis of Type I epithelial cells. In …
Using bleomycin toxicity as an example, it has been shown that, after IV injection, the selective site of lung injury is the vascular endoth …
Ultrastructural aspects of pulmonary edema.
Bachofen H, Bachofen M, Weibel ER. Bachofen H, et al. J Thorac Imaging. 1988 Jul;3(3):1-7. doi: 10.1097/00005382-198807000-00005. J Thorac Imaging. 1988. PMID: 3292779 Review.
As to the routes of abnormal fluid movement, the ultrastructural findings are not always conclusive, though in some types of permeability edema frank anatomic disruptions of the endothelial and epithelial barriers can be observed. ...However, experiments involving m …
As to the routes of abnormal fluid movement, the ultrastructural findings are not always conclusive, though in some types of permeabi …
Cellular and Molecular Mechanisms in Idiopathic Pulmonary Fibrosis.
Zhang Y, Wang J. Zhang Y, et al. Adv Respir Med. 2023 Jan 31;91(1):26-48. doi: 10.3390/arm91010005. Adv Respir Med. 2023. PMID: 36825939 Free PMC article. Review.
The respiratory system is a well-organized multicellular organ, and disruption of cellular homeostasis or abnormal tissue repair caused by genetic deficiency and exposure to risk factors lead to life-threatening pulmonary disease including idiopathic pulmonary fibrosis (IP …
The respiratory system is a well-organized multicellular organ, and disruption of cellular homeostasis or abnormal tissue repair caus …
62 results