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T-cell abnormalities in common variable immunodeficiency: the hidden defect.
Wong GK, Huissoon AP. Wong GK, et al. J Clin Pathol. 2016 Aug;69(8):672-6. doi: 10.1136/jclinpath-2015-203351. Epub 2016 May 6. J Clin Pathol. 2016. PMID: 27153873 Free PMC article. Review.
Although B cells have been the main focus of the disorder, ample experimental data suggest that T-cell abnormalities can be seen in a large proportion of Freiburg Group 1a patients and those suffering from inflammatory complications. The reductions in T-cell recepto …
Although B cells have been the main focus of the disorder, ample experimental data suggest that T-cell abnormalities can be seen in a …
Late effects of radiation on the human immune system: an overview of immune response among the atomic-bomb survivors.
Akiyama M. Akiyama M. Int J Radiat Biol. 1995 Nov;68(5):497-508. doi: 10.1080/09553009514551491. Int J Radiat Biol. 1995. PMID: 7490500 Review.
Abnormalities of T-cell immunity include (1) a decreased proportion of CD3+ T cells in peripheral blood lymphocytes, particularly the proportion of CD4+ CD45RA+ naive T cells (study period 1987-91); (2) an increased frequenc …
Abnormalities of T-cell immunity include (1) a decreased proportion of CD3+ T cells in peripheral blood lymphocy …
Immunological abnormalities in the natural history of HIV infection: mechanisms and clinical relevance.
Miedema F. Miedema F. Immunodefic Rev. 1992;3(3):173-93. Immunodefic Rev. 1992. PMID: 1354968 Review.
In early infection, the in-vivo deletion of memory cells can account for the in-vitro decreased responsiveness. Later on in infection, when the balance between memory and naive T cells is normalized, both CD4 and CD8 cells are non-responsive to nominal antige …
In early infection, the in-vivo deletion of memory cells can account for the in-vitro decreased responsiveness. Later on in infection, when …