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1967
2025

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1967 1
1968 1
1969 2
1971 1
1972 5
1973 1
1974 1
1975 1
1976 6
1977 2
1978 2
1979 1
1980 3
1981 4
1982 2
1983 5
1984 2
1985 2
1986 1
1987 2
1988 4
1989 1
1990 5
1991 2
1992 6
1993 6
1994 12
1995 11
1996 20
1997 20
1998 15
1999 20
2000 28
2001 28
2002 27
2003 17
2004 15
2005 21
2006 21
2007 22
2008 30
2009 29
2010 22
2011 21
2012 20
2013 44
2014 17
2015 16
2016 19
2017 18
2018 18
2019 11
2020 10
2021 13
2022 8
2023 11
2024 9
2025 1

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624 results

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Page 1
Folic acid versus 5- methyl tetrahydrofolate supplementation in pregnancy.
Ferrazzi E, Tiso G, Di Martino D. Ferrazzi E, et al. Eur J Obstet Gynecol Reprod Biol. 2020 Oct;253:312-319. doi: 10.1016/j.ejogrb.2020.06.012. Epub 2020 Jun 13. Eur J Obstet Gynecol Reprod Biol. 2020. PMID: 32868164 Review.
Folate (vitamin B9) is widely accepted to protect against fetal neural tube defects. The main sources of dietary folate are folic acid-fortified foods and folic acid-containing dietary supplements. ...Because 5-MTHF does not require activ
Folate (vitamin B9) is widely accepted to protect against fetal neural tube defects. The main sources of dietary folate are
Spina bifida.
Mitchell LE, Adzick NS, Melchionne J, Pasquariello PS, Sutton LN, Whitehead AS. Mitchell LE, et al. Lancet. 2004 Nov 20-26;364(9448):1885-95. doi: 10.1016/S0140-6736(04)17445-X. Lancet. 2004. PMID: 15555669 Review.
The causes of this disorder are heterogeneous and include chromosome abnormalities, single gene disorders, and teratogenic exposures. However, the cause is not known in most cases. Up to 70% of spina bifida cases can be prevented by maternal, periconceptional folic
The causes of this disorder are heterogeneous and include chromosome abnormalities, single gene disorders, and teratogenic exposures. …
Folic acid and primary prevention of neural tube defects: A review.
van Gool JD, Hirche H, Lax H, De Schaepdrijver L. van Gool JD, et al. Reprod Toxicol. 2018 Sep;80:73-84. doi: 10.1016/j.reprotox.2018.05.004. Epub 2018 May 16. Reprod Toxicol. 2018. PMID: 29777755 Review.
With 4 mg folic acid daily, it may take 20 weeks to reach red-blood-cell folate levels between 1050 and 1340 nmol/L, optimal for reduction of the neural tube defect risk. ...The risk of folate intake >1 mg/day does not outweigh the benefits of fo
With 4 mg folic acid daily, it may take 20 weeks to reach red-blood-cell folate levels between 1050 and 1340 nmol/L, op …
Genetic mimics of cerebral palsy.
Pearson TS, Pons R, Ghaoui R, Sue CM. Pearson TS, et al. Mov Disord. 2019 May;34(5):625-636. doi: 10.1002/mds.27655. Epub 2019 Mar 26. Mov Disord. 2019. PMID: 30913345 Review.
This is particularly important in the case of genetic or metabolic disorders that have specific disease-modifying treatment. In this article, we discuss clinical features that should alert the clinician to the possibility of a cerebral palsy mimic, provide a practical fram …
This is particularly important in the case of genetic or metabolic disorders that have specific disease-modifying treatment. In this …
Nutritional role of folate.
Ebara S. Ebara S. Congenit Anom (Kyoto). 2017 Sep;57(5):138-141. doi: 10.1111/cga.12233. Epub 2017 Jul 25. Congenit Anom (Kyoto). 2017. PMID: 28603928 Review.
It has also been recommended that folate be consumed in the diet to promote the maintenance of good health. To reduce the risk of NTDs, supplementation with folic acid (a synthetic form of folate) during the periconceptional period has also been recomm …
It has also been recommended that folate be consumed in the diet to promote the maintenance of good health. To reduce the risk of NTD …
Evaluation of macrocytosis.
Kaferle J, Strzoda CE. Kaferle J, et al. Am Fam Physician. 2009 Feb 1;79(3):203-8. Am Fam Physician. 2009. PMID: 19202968 Free article. Review.
The most common etiologies are alcoholism, vitamin B12 and folate deficiencies, and medications. History and physical examination, vitamin B12 level, reticulocyte count, and a peripheral smear are helpful in delineating the underlying cause of macrocytosis. When the periph …
The most common etiologies are alcoholism, vitamin B12 and folate deficiencies, and medications. History and physical examination, vi …
High Folate, Perturbed One-Carbon Metabolism and Gestational Diabetes Mellitus.
Williamson JM, Arthurs AL, Smith MD, Roberts CT, Jankovic-Karasoulos T. Williamson JM, et al. Nutrients. 2022 Sep 22;14(19):3930. doi: 10.3390/nu14193930. Nutrients. 2022. PMID: 36235580 Free PMC article. Review.
Folate is a dietary micronutrient essential to one-carbon metabolism. The World Health Organisation recommends folic acid (FA) supplementation pre-conception and in early pregnancy to reduce the risk of fetal neural tube defects (NTDs). ...However, hum
Folate is a dietary micronutrient essential to one-carbon metabolism. The World Health Organisation recommends folic
Vitamins and type 2 diabetes mellitus.
Valdés-Ramos R, Guadarrama-López AL, Martínez-Carrillo BE, Benítez-Arciniega AD. Valdés-Ramos R, et al. Endocr Metab Immune Disord Drug Targets. 2015;15(1):54-63. doi: 10.2174/1871530314666141111103217. Endocr Metab Immune Disord Drug Targets. 2015. PMID: 25388747 Free PMC article. Review.
With respect to the B group vitamins, thiamin, pyridoxine and biotin have been found decreased but the mechanisms are not clear, however supplementation has shown some improvement of the metabolic control in diabetic patients. The absorption of folic acid and …
With respect to the B group vitamins, thiamin, pyridoxine and biotin have been found decreased but the mechanisms are not clear, however sup …
Homocysteine Modification in Protein Structure/Function and Human Disease.
Jakubowski H. Jakubowski H. Physiol Rev. 2019 Jan 1;99(1):555-604. doi: 10.1152/physrev.00003.2018. Physiol Rev. 2019. PMID: 30427275 Free article. Review.
Epidemiological studies established that elevated homocysteine, an important intermediate in folate, vitamin B(12), and one carbon metabolism, is associated with poor health, including heart and brain diseases. Earlier studies show that patients with severe hyperhom …
Epidemiological studies established that elevated homocysteine, an important intermediate in folate, vitamin B(12), and one carbon …
Risk factors for Down syndrome.
Coppedè F. Coppedè F. Arch Toxicol. 2016 Dec;90(12):2917-2929. doi: 10.1007/s00204-016-1843-3. Epub 2016 Sep 7. Arch Toxicol. 2016. PMID: 27600794 Review.
This article critically reviews the hypotheses and the risk factors which have been suggested to contribute to the birth of a child with DS, including folate metabolism, dietary, lifestyle, environmental, occupational, genetic and epigenetic factors, with focus on m …
This article critically reviews the hypotheses and the risk factors which have been suggested to contribute to the birth of a child with DS, …
624 results