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Growth and endocrine function in thalassemia major in childhood and adolescence.
Delvecchio M, Cavallo L. Delvecchio M, et al. J Endocrinol Invest. 2010 Jan;33(1):61-8. doi: 10.1007/BF03346551. J Endocrinol Invest. 2010. PMID: 20203539 Review.
RESULTS: Disproportionate short stature is frequent and becomes more evident at puberty because of the lack of growth spurt. Later on, partial height recovery may occur. Long-term treatment with recombinant human GH seems ineffective to improve final height. Pube
RESULTS: Disproportionate short stature is frequent and becomes more evident at puberty because of the lack of growth spurt. L …
The multifactorial origin of growth failure in thalassaemia.
Skordis N, Kyriakou A. Skordis N, et al. Pediatr Endocrinol Rev. 2011 Mar;8 Suppl 2:271-7. Pediatr Endocrinol Rev. 2011. PMID: 21705977 Review.
The child with TM has a particular growth pattern, which is relatively normal until age 9-10 years; after this age a slowing down of growth velocity and reduced or absent pubertal growth spurt are observed. ...Although appropriate iron ch …
The child with TM has a particular growth pattern, which is relatively normal until age 9-10 years; after this age a slowing down of …
Management of puberty in growth hormone deficient children.
Rogol AD. Rogol AD. Endocr J. 1996 Oct;43(Suppl):S5-11. doi: 10.1507/endocrj.43.suppl_s5. Endocr J. 1996. PMID: 9076336 Free article. Review.
An important physiological synergism exists between the gonadal and somatotropic axes to permit the growth spurt and adolescent development; however, epiphyseal maturation is also accelerated leading to cessation of long-bone growth. GH deficiency may …
An important physiological synergism exists between the gonadal and somatotropic axes to permit the growth spurt and adolescen …
Endocrine complications in patients with Thalassaemia Major.
Toumba M, Sergis A, Kanaris C, Skordis N. Toumba M, et al. Pediatr Endocrinol Rev. 2007 Dec;5(2):642-8. Pediatr Endocrinol Rev. 2007. PMID: 18084158 Review.
A multicenter study in Cyprus including 435 patients showed hypogonadotrophic hypogonadism in 32.5%, short stature in 35%, acquired hypothyroidism in 5.9%, hypoparathyroidism in 1.2% and diabetes mellitus in 9.4%. A slowing down of growth velocity and a reduced or absen
A multicenter study in Cyprus including 435 patients showed hypogonadotrophic hypogonadism in 32.5%, short stature in 35%, acquired hypothyr …