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Estimating allele age.
Slatkin M, Rannala B. Slatkin M, et al. Annu Rev Genomics Hum Genet. 2000;1:225-49. doi: 10.1146/annurev.genom.1.1.225. Annu Rev Genomics Hum Genet. 2000. PMID: 11701630 Review.
These methods have been applied to numerous cases, including alleles associated with cystic fibrosis, idiopathic torsion dystonia, and resistance to infection by HIV. We emphasize that estimates of allele age depend on assumptions about demographic history an …
These methods have been applied to numerous cases, including alleles associated with cystic fibrosis, idiopathic torsion dy
Genetic and clinical features of primary torsion dystonia.
Ozelius LJ, Bressman SB. Ozelius LJ, et al. Neurobiol Dis. 2011 May;42(2):127-35. doi: 10.1016/j.nbd.2010.12.012. Epub 2010 Dec 17. Neurobiol Dis. 2011. PMID: 21168499 Free PMC article. Review.
Primary torsion dystonia (PTD) is defined as a syndrome in which dystonia is the only clinical sign (except for tremor), and there is no evidence of neuronal degeneration or an acquired cause by history or routine laboratory assessment. ...This article …
Primary torsion dystonia (PTD) is defined as a syndrome in which dystonia is the only clinical sign (except for tremor) …
Genetics and pharmacological treatment of dystonia.
Barrett MJ, Bressman S. Barrett MJ, et al. Int Rev Neurobiol. 2011;98:525-49. doi: 10.1016/B978-0-12-381328-2.00019-5. Int Rev Neurobiol. 2011. PMID: 21907099 Review.
Dystonia consists of involuntary repetitive twisting (torsion) or directional movements, sometimes leading to sustained postures. ...Dystonia can be considered either primary or nonprimary. Primary torsion dystonia (PTD), historically called
Dystonia consists of involuntary repetitive twisting (torsion) or directional movements, sometimes leading to sustained postur