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2025

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Oxidative Stress: A Key Modulator in Neurodegenerative Diseases.
Singh A, Kukreti R, Saso L, Kukreti S. Singh A, et al. Molecules. 2019 Apr 22;24(8):1583. doi: 10.3390/molecules24081583. Molecules. 2019. PMID: 31013638 Free PMC article. Review.
Apart from this, the neuronal membranes are found to be rich in polyunsaturated fatty acids, which are highly susceptible to ROS. Various neurodegenerative diseases such as Parkinson's disease (PD), Alzheimer's disease (AD), Huntington's disease (HD), …
Apart from this, the neuronal membranes are found to be rich in polyunsaturated fatty acids, which are highly susceptible to ROS. Var …
Consequences of Disturbing Manganese Homeostasis.
Baj J, Flieger W, Barbachowska A, Kowalska B, Flieger M, Forma A, Teresiński G, Portincasa P, Buszewicz G, Radzikowska-Büchner E, Flieger J. Baj J, et al. Int J Mol Sci. 2023 Oct 6;24(19):14959. doi: 10.3390/ijms241914959. Int J Mol Sci. 2023. PMID: 37834407 Free PMC article. Review.
Associations have been observed between Mn accumulation and neurodegenerative diseases such as manganism, Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis. ...The disturbed homeostasis of M …
Associations have been observed between Mn accumulation and neurodegenerative diseases such as manganism, Alzheimer's disease, Parkin …
Amyotrophic Lateral Sclerosis Pathoetiology and Pathophysiology: Roles of Astrocytes, Gut Microbiome, and Muscle Interactions via the Mitochondrial Melatonergic Pathway, with Disruption by Glyphosate-Based Herbicides.
Anderson G. Anderson G. Int J Mol Sci. 2022 Dec 29;24(1):587. doi: 10.3390/ijms24010587. Int J Mol Sci. 2022. PMID: 36614029 Free PMC article. Review.
The pathoetiology and pathophysiology of motor neuron loss in amyotrophic lateral sclerosis (ALS) are still to be determined, with only a small percentage of ALS patients having a known genetic risk factor. ...Such maintained astrocyte activation, coupled wit …
The pathoetiology and pathophysiology of motor neuron loss in amyotrophic lateral sclerosis (ALS) are still to be deter …
Neurotoxicity of Insecticides.
Cassereau J, Ferré M, Chevrollier A, Codron P, Verny C, Homedan C, Lenaers G, Procaccio V, May-Panloup P, Reynier P. Cassereau J, et al. Curr Med Chem. 2017;24(27):2988-3001. doi: 10.2174/0929867324666170526122654. Curr Med Chem. 2017. PMID: 28552054 Review.
Parkinson's and Alzheimer's diseases, amyotrophic lateral sclerosis, and depression, have been regularly associated with insecticide exposure. ...However, the tardive appearance of neurodegenerative disorders and the large variability of inter-individual s
Parkinson's and Alzheimer's diseases, amyotrophic lateral sclerosis, and depression, have been regularly associated wit …
Cerebrotendinous xanthomatosis.
Björkhem I. Björkhem I. Curr Opin Lipidol. 2013 Aug;24(4):283-7. doi: 10.1097/MOL.0b013e328362df13. Curr Opin Lipidol. 2013. PMID: 23759795 Review.
PURPOSE OF REVIEW: Cerebrotendinous xanthomatosis (CTX) is a rare neurological disease characterized by accumulation of cholesterol and cholestanol in brain and tendons caused by a mutation in the sterol 27-hydroxylase gene (CYP27A1). ...CYP27A1 was identified as a candida …
PURPOSE OF REVIEW: Cerebrotendinous xanthomatosis (CTX) is a rare neurological disease characterized by accumulation of cholesterol a …
From Recognition to Remedy: The Significance of Biomarkers in Neurodegenerative Disease Pathology.
Toader C, Dobrin N, Brehar FM, Popa C, Covache-Busuioc RA, Glavan LA, Costin HP, Bratu BG, Corlatescu AD, Popa AA, Ciurea AV. Toader C, et al. Int J Mol Sci. 2023 Nov 9;24(22):16119. doi: 10.3390/ijms242216119. Int J Mol Sci. 2023. PMID: 38003309 Free PMC article. Review.
With the inexorable aging of the global populace, neurodegenerative diseases (NDs) like Alzheimer's disease (AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS) pose escalating challenges, which are underscored by their socioe …
With the inexorable aging of the global populace, neurodegenerative diseases (NDs) like Alzheimer's disease (AD), Parkinson's dise
Proteasome Activation to Combat Proteotoxicity.
Jones CL, Tepe JJ. Jones CL, et al. Molecules. 2019 Aug 5;24(15):2841. doi: 10.3390/molecules24152841. Molecules. 2019. PMID: 31387243 Free PMC article. Review.
These misfolded and aggregated species are often found, and suggested to be the culpable party, in numerous neurodegenerative diseases including Huntington's, Parkinson's, Amyotrophic Lateral Sclerosis (ALS), and Alzheimer's Diseases (AD). Many strategies for …
These misfolded and aggregated species are often found, and suggested to be the culpable party, in numerous neurodegenerative diseases inclu …
Systematic Review and Meta-Analyses of Aminopeptidases as Prognostic Biomarkers in Amyotrophic Lateral Sclerosis.
Teruel-Peña B, Gómez-Urquiza JL, Suleiman-Martos N, Prieto I, García-Cózar FJ, Ramírez-Sánchez M, Fernández-Martos C, Domínguez-Vías G. Teruel-Peña B, et al. Int J Mol Sci. 2023 Apr 12;24(8):7169. doi: 10.3390/ijms24087169. Int J Mol Sci. 2023. PMID: 37108335 Free PMC article. Review.
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive loss of motor neurons in the spinal cord, brain stem, and cerebral cortex. Biomarkers for ALS are essential for disease detection and to pr
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive loss o
Clinical and demographic factors and outcome of amyotrophic lateral sclerosis in relation to population ancestral origin.
Marin B, Logroscino G, Boumédiene F, Labrunie A, Couratier P, Babron MC, Leutenegger AL, Preux PM, Beghi E. Marin B, et al. Eur J Epidemiol. 2016 Mar;31(3):229-45. doi: 10.1007/s10654-015-0090-x. Epub 2015 Oct 12. Eur J Epidemiol. 2016. PMID: 26458931 Review.
BACKGROUND: To review how the phenotype and outcome of amyotrophic lateral sclerosis (ALS) change with variations in population ancestral origin (PAO). Knowledge of how PAO modifies ALS phenotype may provide important insight into the risk factors and pathoge …
BACKGROUND: To review how the phenotype and outcome of amyotrophic lateral sclerosis (ALS) change with variations in po …
Multiple sclerosis and amyotrophic lateral sclerosis: is there an association or a red flag? A case report and literature review.
Aljthalin R, Albalawi R, Alyahya A, Alhathlool R, Alhashemi M. Aljthalin R, et al. BMC Neurol. 2024 Aug 31;24(1):307. doi: 10.1186/s12883-024-03821-x. BMC Neurol. 2024. PMID: 39217293 Free PMC article. Review.
BACKGROUND: Multiple sclerosis (MS) is an inflammatory disease of the central nervous system that causes damage to the myelin and axons and is caused by genetic or environmental factors. Amyotrophic lateral sclerosis (ALS) is characterized by ra …
BACKGROUND: Multiple sclerosis (MS) is an inflammatory disease of the central nervous system that causes damage to the myelin …
12 results