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2025

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1995 1
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2008 1
2009 1
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Page 1
Sickle Cell Disease: A Review.
Kavanagh PL, Fasipe TA, Wun T. Kavanagh PL, et al. JAMA. 2022 Jul 5;328(1):57-68. doi: 10.1001/jama.2022.10233. JAMA. 2022. PMID: 35788790 Review.
OBSERVATIONS: SCD is diagnosed through newborn screening programs, where available, or when patients present with unexplained severe atraumatic pain or normocytic anemia. In SCD, sickling and hemolysis of red blood cells result in vaso-occlusion with associat …
OBSERVATIONS: SCD is diagnosed through newborn screening programs, where available, or when patients present with unexplained severe atrauma …
Laboratory Approach to Hemolytic Anemia.
Jamwal M, Sharma P, Das R. Jamwal M, et al. Indian J Pediatr. 2020 Jan;87(1):66-74. doi: 10.1007/s12098-019-03119-8. Epub 2019 Dec 10. Indian J Pediatr. 2020. PMID: 31823208 Review.
Hemolytic anemias are a group of disorders with varied clinical and molecular heterogeneity. They are characterized by decreased levels of circulating erythrocytes in blood. The pathognomic finding is a reduced red cell life span with sev …
Hemolytic anemias are a group of disorders with varied clinical and molecular heterogeneity. They are characterized by decreased leve …
Sickle cell anemia, the first molecular disease: overview of molecular etiology, pathophysiology, and therapeutic approaches.
Steinberg MH. Steinberg MH. ScientificWorldJournal. 2008 Dec 25;8:1295-324. doi: 10.1100/tsw.2008.157. ScientificWorldJournal. 2008. PMID: 19112541 Free PMC article. Review.
A multifaceted pathophysiology, triggered by erythrocyte injury induced by the sickle hemoglobin polymer, and encompassing more general cellular and tissue damage caused by hypoxia, oxidant damage, inflammation, abnormal intracellular interactions, and reduced nitric oxide …
A multifaceted pathophysiology, triggered by erythrocyte injury induced by the sickle hemoglobin polymer, and encompassing more general cell …
Red Blood Cells as Therapeutic Target to Treat Sickle Cell Disease.
Bhatt S, Argueta DA, Gupta K, Kundu S. Bhatt S, et al. Antioxid Redox Signal. 2024 Jun;40(16-18):1025-1049. doi: 10.1089/ars.2023.0348. Epub 2024 Jan 23. Antioxid Redox Signal. 2024. PMID: 37975291 Review.
SCD is characterized by chronic pain and fatigue, severe acute painful crises requiring hospitalization and opioids, strokes, multiorgan damage, and a shortened life span. Symptoms may appear shortly after birth, and, in less developed countries, most children with …
SCD is characterized by chronic pain and fatigue, severe acute painful crises requiring hospitalization and opioids, strokes, multiorgan dam …
Red cell membrane disorders.
Narla J, Mohandas N. Narla J, et al. Int J Lab Hematol. 2017 May;39 Suppl 1:47-52. doi: 10.1111/ijlh.12657. Int J Lab Hematol. 2017. PMID: 28447420 Review.
Significant advances have been made in our understanding of the structural basis for altered cell function in various inherited red cell membrane disorders with reduced red cell survival and resulting hemolytic anemia. ...The degrees of membrane loss a …
Significant advances have been made in our understanding of the structural basis for altered cell function in various inherited red c …
Pathophysiology of renal anemia.
Eckardt KU. Eckardt KU. Clin Nephrol. 2000 Feb;53(1 Suppl):S2-8. Clin Nephrol. 2000. PMID: 10746799 Review.
The reasons include: 1) a moderately reduced red cell life span, 2) blood loss, and 3) an inadequate increase in erythropoiesis relative to the fall in hemoglobin (Hb). The life-span of red blood cells may be shortened by th …
The reasons include: 1) a moderately reduced red cell life span, 2) blood loss, and 3) an inadequate increase in …
Role of nutrition on anemia in elderly.
Bianchi VE. Bianchi VE. Clin Nutr ESPEN. 2016 Feb;11:e1-e11. doi: 10.1016/j.clnesp.2015.09.003. Epub 2015 Dec 9. Clin Nutr ESPEN. 2016. PMID: 28531420 Review.
Macrophages activity is inhibited and a decrease in red blood cells (RBC), hemoglobin (Hb) concentration due to ineffective erythropoiesis is observed. ...The supplementation of vitamins and oligomineral are useful to reduce oxidative stress and improve RBC …
Macrophages activity is inhibited and a decrease in red blood cells (RBC), hemoglobin (Hb) concentration due to ineffective er …
Biological basis of anemia.
Bron D, Meuleman N, Mascaux C. Bron D, et al. Semin Oncol. 2001 Apr;28(2 Suppl 8):1-6. doi: 10.1016/s0093-7754(01)90205-2. Semin Oncol. 2001. PMID: 11395845 Review.
The syndrome of anemia of chronic disease is characterized by a hyporegenerative, normocytic, normochromic anemia associated with reduced serum iron and transferrin saturation but elevated (or normal) ferritin levels. ...The cytokine-mediated relative failure …
The syndrome of anemia of chronic disease is characterized by a hyporegenerative, normocytic, normochromic anemia associated w …
Inherited hemolytic anemia: a possessive beginner's guide.
Mohandas N. Mohandas N. Hematology Am Soc Hematol Educ Program. 2018 Nov 30;2018(1):377-381. doi: 10.1182/asheducation-2018.1.377. Hematology Am Soc Hematol Educ Program. 2018. PMID: 30504335 Free PMC article. Review.
The degrees of membrane loss and resultant increases in cell sphericity determine the severity of anemia in HS and HE, and splenectomy leads to amelioration of anemia by increasing the circulatory red cell life span. Alterations in cell volume a …
The degrees of membrane loss and resultant increases in cell sphericity determine the severity of anemia in HS and HE, and splenectom …
Congenital Hemolytic Anemias: Is There a Role for the Immune System?
Zaninoni A, Fermo E, Vercellati C, Marcello AP, Barcellini W, Bianchi P. Zaninoni A, et al. Front Immunol. 2020 Jun 23;11:1309. doi: 10.3389/fimmu.2020.01309. eCollection 2020. Front Immunol. 2020. PMID: 32655575 Free PMC article. Review.
Congenital hemolytic anemias (CHAs) are a heterogeneous group of rare hereditary conditions including defects of erythrocyte membrane proteins, red cell enzymes, and disorders due to defective erythropoiesis. They are characterized by variable degree of anemia
Congenital hemolytic anemias (CHAs) are a heterogeneous group of rare hereditary conditions including defects of erythrocyte membrane …
22 results