ABCC6, Pyrophosphate and Ectopic Calcification: Therapeutic Solutions.
Shimada BK, Pomozi V, Zoll J, Kuo S, Martin L, Le Saux O.
Shimada BK, et al.
Int J Mol Sci. 2021 Apr 27;22(9):4555. doi: 10.3390/ijms22094555.
Int J Mol Sci. 2021.
PMID: 33925341
Free PMC article.
Review.
ABCC6 dysfunction is the primary cause of PXE, but also some cases of generalized arterial calcification of infancy (GACI). ABCC6 deficiency in mice underlies an inducible dystrophic cardiac calcification phenotype (DCC). ...
ABCC6 dysfunction is the primary cause of PXE, but also some cases of generalized arterial calcification of infancy …