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2007 3
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Page 1
Hereditary ovarian carcinoma.
Gallion HH, Smith SA. Gallion HH, et al. Semin Surg Oncol. 1994 Jul-Aug;10(4):249-54. doi: 10.1002/ssu.2980100404. Semin Surg Oncol. 1994. PMID: 8091066 Review.
More recently, genetic predisposition has been recognized as a strong risk factor for ovarian cancer. Three distinct hereditary syndromes have been identified: (1) breast-ovarian cancer syndrome, (2) hereditary nonpolyposis colon cancer, …
More recently, genetic predisposition has been recognized as a strong risk factor for ovarian cancer. Three distinct hereditary syndr …
Hereditary cancer syndromes.
Fostira F, Thodi G, Konstantopoulou I, Sandaltzopoulos R, Yannoukakos D. Fostira F, et al. J BUON. 2007 Sep;12 Suppl 1:S13-22. J BUON. 2007. PMID: 17935271 Review.
The identification of susceptibility genes for specific types of cancer provided the necessary information for the complete characterization of inherited cancer syndromes. ...This review reports the most characteristic hereditary cancer syndromes along …
The identification of susceptibility genes for specific types of cancer provided the necessary information for the complete ch …
BRCA1: An Endocrine and Metabolic Regulator.
Werner H. Werner H. Front Endocrinol (Lausanne). 2022 Mar 31;13:844575. doi: 10.3389/fendo.2022.844575. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 35432218 Free PMC article. Review.
The breast and ovarian cancer susceptibility gene (BRCA1) is a tumor suppressor whose mutation has been associated with the development of breast, ovarian and, probably, other malignancies at young ages. ...Inactivating germline mutations of the BRCA1 …
The breast and ovarian cancer susceptibility gene (BRCA1) is a tumor suppressor whose mutation has been associated with the de …
Current Approaches to Pancreatic Cancer Screening.
Chhoda A, Lu L, Clerkin BM, Risch H, Farrell JJ. Chhoda A, et al. Am J Pathol. 2019 Jan;189(1):22-35. doi: 10.1016/j.ajpath.2018.09.013. Am J Pathol. 2019. PMID: 30558719 Free article. Review.
However, screening may be beneficial for individuals with familial history, chronic diseases with genetic predispositions, or inherited cancer syndromes, such as hereditary breast ovarian cancer syndrome, hereditary pancreatitis, Peutz-Jeghers s …
However, screening may be beneficial for individuals with familial history, chronic diseases with genetic predispositions, or inherit …
BRCA2 gene mutation and prostate cancer risk. Comprehensive review and update.
Junejo NN, AlKhateeb SS. Junejo NN, et al. Saudi Med J. 2020 Jan;41(1):9-17. doi: 10.15537/smj.2020.1.24759. Saudi Med J. 2020. PMID: 31915789 Free PMC article. Review.
BRCA1 and BRCA2 mutations have linked with an increased risk for breast, ovarian, and PCa. However, BRCA2 is the most common gene found altered in early-onset of PCa in males younger than 65. BRCA2 mutation has a higher chance of developing an advanced stage of the …
BRCA1 and BRCA2 mutations have linked with an increased risk for breast, ovarian, and PCa. However, BRCA2 is the most common g …
Hereditary Cancer Syndromes-A Primer on Diagnosis and Management: Part 1: Breast-Ovarian Cancer Syndromes.
Samadder NJ, Giridhar KV, Baffy N, Riegert-Johnson D, Couch FJ. Samadder NJ, et al. Mayo Clin Proc. 2019 Jun;94(6):1084-1098. doi: 10.1016/j.mayocp.2019.02.017. Mayo Clin Proc. 2019. PMID: 31171119 Review.
Hereditary causes occurring due to pathogenic sequence variants and defects in certain genes makes up roughly 5% of all colorectal cancers and breast-ovarian cancers. High-risk hereditary predisposition syndromes have been associated with a substantial …
Hereditary causes occurring due to pathogenic sequence variants and defects in certain genes makes up roughly 5% of all colorectal cancer
Breast cancer risk and clinical implications for germline PTEN mutation carriers.
Ngeow J, Sesock K, Eng C. Ngeow J, et al. Breast Cancer Res Treat. 2017 Aug;165(1):1-8. doi: 10.1007/s10549-015-3665-z. Epub 2015 Dec 23. Breast Cancer Res Treat. 2017. PMID: 26700035 Review.
PHTS can be differentiated from other hereditary cancer syndromes including Hereditary Breast Ovarian Cancer syndrome, Lynch syndrome, and hamartomatous polyposis syndromes based on personal as well as family history. However, many of the benign …
PHTS can be differentiated from other hereditary cancer syndromes including Hereditary Breast Ovarian Cancer syn …
Hereditary ovarian cancer.
Langston AA, Ostrander EA. Langston AA, et al. Curr Opin Obstet Gynecol. 1997 Feb;9(1):3-7. Curr Opin Obstet Gynecol. 1997. PMID: 9090474 Review.
Ovarian cancer has been described in association with three autosomal dominant syndromes: familial site-specific ovarian cancer, familial breast and ovarian cancer, and the hereditary nonpolyposis colon cancer syndrome. It appears that mo …
Ovarian cancer has been described in association with three autosomal dominant syndromes: familial site-specific ovarian ca
Hereditary breast cancer: part I. Diagnosing hereditary breast cancer syndromes.
Lynch HT, Silva E, Snyder C, Lynch JF. Lynch HT, et al. Breast J. 2008 Jan-Feb;14(1):3-13. doi: 10.1111/j.1524-4741.2007.00515.x. Epub 2007 Dec 11. Breast J. 2008. PMID: 18086272 Review.
Therefore, when these numbers are combined, familial BC risk accounts for approximately 20-25% of the total BC burden. However, because of the often limited information on family history in the etiologic assessment of BC, this may be an underestimate. Confounding fa …
Therefore, when these numbers are combined, familial BC risk accounts for approximately 20-25% of the total BC burden. However, becau …
The molecular genetics of hereditary and sporadic ovarian cancer: implications for the future.
Al Bakir M, Gabra H. Al Bakir M, et al. Br Med Bull. 2014 Dec;112(1):57-69. doi: 10.1093/bmb/ldu034. Br Med Bull. 2014. PMID: 25473022 Review.
INTRODUCTION: Epithelial ovarian cancer (EOC) is a heterogeneous condition with poor survival outcomes. The genetics of hereditary and sporadic ovarian cancers will be covered and its implications to management and future research are discussed. ...The commonest her …
INTRODUCTION: Epithelial ovarian cancer (EOC) is a heterogeneous condition with poor survival outcomes. The genetics of hereditary an …
24 results