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1968
2025

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1968 2
1971 2
1973 1
1974 1
1975 4
1978 1
1979 1
1980 2
1982 1
1983 3
1984 3
1985 2
1986 3
1987 2
1988 5
1989 7
1990 1
1991 8
1992 10
1993 3
1994 12
1995 4
1996 5
1997 5
1998 3
1999 8
2000 6
2001 4
2002 17
2003 7
2004 5
2005 6
2006 7
2007 7
2008 9
2009 11
2010 8
2011 11
2012 14
2013 10
2014 7
2015 14
2016 9
2017 10
2018 13
2019 5
2020 14
2021 17
2022 17
2023 18
2024 8
2025 0

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324 results

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Page 1
Genetic and Epigenetic Control of Puberty.
Manotas MC, González DM, Céspedes C, Forero C, Rojas Moreno AP. Manotas MC, et al. Sex Dev. 2022;16(1):1-10. doi: 10.1159/000519039. Epub 2021 Oct 14. Sex Dev. 2022. PMID: 34649256 Free PMC article. Review.
Puberty is a complex transitional phase in which reproductive capacity is achieved. There is a very wide variation in the age range of the onset of puberty, which follows a familial, ethnic, and sex pattern. ...All these factors can influence normal puberty t
Puberty is a complex transitional phase in which reproductive capacity is achieved. There is a very wide variation in the age range o
The Role of Kisspeptin in the Control of the Hypothalamic-Pituitary-Gonadal Axis and Reproduction.
Xie Q, Kang Y, Zhang C, Xie Y, Wang C, Liu J, Yu C, Zhao H, Huang D. Xie Q, et al. Front Endocrinol (Lausanne). 2022 Jun 28;13:925206. doi: 10.3389/fendo.2022.925206. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 35837314 Free PMC article. Review.
The discovery of kisspeptin as a critical central regulatory factor of GnRH release has given people a novel understanding of the neuroendocrine regulation in human reproduction. ...Mutations in the KISS1 gene or disorders of the kisspeptin/KISS1R system may lead to clinic …
The discovery of kisspeptin as a critical central regulatory factor of GnRH release has given people a novel understanding of the neu …
Precocious puberty and normal variant puberty: definition, etiology, diagnosis and current management.
Berberoğlu M. Berberoğlu M. J Clin Res Pediatr Endocrinol. 2009;1(4):164-74. doi: 10.4274/jcrpe.v1i4.3. Epub 2009 May 2. J Clin Res Pediatr Endocrinol. 2009. PMID: 21274291 Free PMC article. Review.
This review describes several aspects of the management of precocious puberty (PP) and variants in girls and boys. PP is characterized by early pubertal changes, acceleration of growth velocity and rapid bone maturation that often result in reduced adult height. ...
This review describes several aspects of the management of precocious puberty (PP) and variants in girls and boys. PP is chara …
GENETICS IN ENDOCRINOLOGY: Genetic etiologies of central precocious puberty and the role of imprinted genes.
Roberts SA, Kaiser UB. Roberts SA, et al. Eur J Endocrinol. 2020 Oct;183(4):R107-R117. doi: 10.1530/EJE-20-0103. Eur J Endocrinol. 2020. PMID: 32698138 Free PMC article. Review.
Criteria for determining normal pubertal timing, and thus the definition of precocious puberty, have evolved based on published population studies. The significance of the genetic influence on pubertal timing is supported by familial pubertal timing and twin studies …
Criteria for determining normal pubertal timing, and thus the definition of precocious puberty, have evolved based on publishe …
Genetic, epigenetic and enviromental influencing factors on the regulation of precocious and delayed puberty.
Faienza MF, Urbano F, Moscogiuri LA, Chiarito M, De Santis S, Giordano P. Faienza MF, et al. Front Endocrinol (Lausanne). 2022 Dec 22;13:1019468. doi: 10.3389/fendo.2022.1019468. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36619551 Free PMC article. Review.
Although the transition from pre-pubertal condition to puberty occurs physiologically in a delimited age-range, the inception of pubertal development can be anticipated or delayed due to genetic and epigenetic changes or environmental conditions. ...This review aims to inv …
Although the transition from pre-pubertal condition to puberty occurs physiologically in a delimited age-range, the inception of pube …
Precocious puberty in narcolepsy type 1: Orexin loss and/or neuroinflammation, which is to blame?
Melzi S, Prevot V, Peyron C. Melzi S, et al. Sleep Med Rev. 2022 Oct;65:101683. doi: 10.1016/j.smrv.2022.101683. Epub 2022 Sep 10. Sleep Med Rev. 2022. PMID: 36096986 Free article. Review.
Overweight/obesity and precocious puberty are highly prevalent comorbidities of NT1, with a close temporal correlation with disease onset, suggesting a common origin. ...Orexin/hypocretin replacement could thus be envisaged as a potential treatment for precocious
Overweight/obesity and precocious puberty are highly prevalent comorbidities of NT1, with a close temporal correlation with di …
Diet and Nutrients Intakes during Infancy and Childhood in Relation to Early Puberty: A Systematic Review and Meta-Analysis.
Tang J, Xue P, Huang X, Lin C, Liu S. Tang J, et al. Nutrients. 2022 Nov 24;14(23):5004. doi: 10.3390/nu14235004. Nutrients. 2022. PMID: 36501034 Free PMC article. Review.
The onset of puberty has become earlier over the decades, and nutrients and diet are related to the timing of puberty onset. ...Conversely, due to the high intake of protein, the risk of early menarche increased by 8% (RR 1.08, 95% CI: 1.01, 1.1 …
The onset of puberty has become earlier over the decades, and nutrients and diet are related to the timing of puberty onset. . …
Premature Thelarche.
Khokhar A, Mojica A. Khokhar A, et al. Pediatr Ann. 2018 Jan 1;47(1):e12-e15. doi: 10.3928/19382359-20171214-01. Pediatr Ann. 2018. PMID: 29323691 Review.
Premature thelarche is a benign condition that affects young girls and may be interpreted as a sign of central precocious puberty (CPP). Parental concern is common when breast development is noted in a young girl. ...This article reviews the clinical presenta …
Premature thelarche is a benign condition that affects young girls and may be interpreted as a sign of central precocious p
Kisspeptin antagonists.
Roseweir AK, Millar RP. Roseweir AK, et al. Adv Exp Med Biol. 2013;784:159-86. doi: 10.1007/978-1-4614-6199-9_8. Adv Exp Med Biol. 2013. PMID: 23550006 Review.
The development of peripherally active kisspeptin antagonists could offer a unique therapeutic agent for treating hormone-dependent disorders of reproduction, including precocious puberty, endometriosis, and metastatic prostate cancer. The following chapter discusse …
The development of peripherally active kisspeptin antagonists could offer a unique therapeutic agent for treating hormone-dependent disorder …
Herbal Medicine for Idiopathic Central Precocious Puberty: A Systematic Review and Meta-Analysis.
Lee YB, Lee JA, Lee HL. Lee YB, et al. J Altern Complement Med. 2020 Nov;26(11):976-999. doi: 10.1089/acm.2019.0312. Epub 2020 Jul 10. J Altern Complement Med. 2020. PMID: 32654496
Introduction: Herbal medicine (HM) is widely used in East Asia to treat idiopathic central precocious puberty (ICPP). However, no systematic reviews of the efficacy and safety of HM for treatment of ICPP have been reported. ...As a result of meta-analysis, re …
Introduction: Herbal medicine (HM) is widely used in East Asia to treat idiopathic central precocious puberty (ICPP). H …
324 results