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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 1
1969 1
1971 1
1974 1
1975 1
1976 4
1977 3
1978 1
1979 4
1980 4
1982 2
1983 7
1984 4
1985 4
1986 2
1987 6
1988 10
1989 14
1990 11
1991 13
1992 15
1993 17
1994 21
1995 23
1996 25
1997 24
1998 32
1999 32
2000 41
2001 38
2002 46
2003 39
2004 33
2005 51
2006 44
2007 36
2008 44
2009 49
2010 59
2011 52
2012 57
2013 64
2014 48
2015 64
2016 62
2017 82
2018 66
2019 77
2020 69
2021 62
2022 51
2023 58
2024 20

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Search Results

1,476 results

Results by year

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Page 1
Liver cirrhosis.
Ginès P, Krag A, Abraldes JG, Solà E, Fabrellas N, Kamath PS. Ginès P, et al. Lancet. 2021 Oct 9;398(10308):1359-1376. doi: 10.1016/S0140-6736(21)01374-X. Epub 2021 Sep 17. Lancet. 2021. PMID: 34543610 Review.
Cirrhosis is widely prevalent worldwide and can be a consequence of different causes, such as obesity, non-alcoholic fatty liver disease, high alcohol consumption, hepatitis B or C infection, autoimmune diseases, cholestatic diseases, and iron o …
Cirrhosis is widely prevalent worldwide and can be a consequence of different causes, such as obesity, non-alcoholic fatty liver d
Novel therapeutic targets for cholestatic and fatty liver disease.
Trauner M, Fuchs CD. Trauner M, et al. Gut. 2022 Jan;71(1):194-209. doi: 10.1136/gutjnl-2021-324305. Epub 2021 Oct 6. Gut. 2022. PMID: 34615727 Free PMC article. Review.
Cholestatic and non-alcoholic fatty liver disease (NAFLD) share several key pathophysiological mechanisms which can be targeted by novel therapeutic concepts that are currently developed for both areas. ...Dysregulation of these processes contributes to the p
Cholestatic and non-alcoholic fatty liver disease (NAFLD) share several key pathophysiological mechanisms which can be
Neonatal Cholestasis: Updates on Diagnostics, Therapeutics, and Prevention.
Feldman AG, Sokol RJ. Feldman AG, et al. Neoreviews. 2021 Dec 1;22(12):e819-e836. doi: 10.1542/neo.22-12-e819. Neoreviews. 2021. PMID: 34850148 Free PMC article. Review.
In the past 2 decades, genetic etiologies have been elucidated for many cholestatic diseases, and next-generation sequencing, whole-exome sequencing, and whole-genome sequencing now allow for relatively rapid and cost-effective diagnosis of conditions not previously …
In the past 2 decades, genetic etiologies have been elucidated for many cholestatic diseases, and next-generation sequencing, …
Evaluation of Jaundice in Adults.
Fargo MV, Grogan SP, Saguil A. Fargo MV, et al. Am Fam Physician. 2017 Feb 1;95(3):164-168. Am Fam Physician. 2017. PMID: 28145671 Free article. Review.
Jaundice in adults can be an indicator of significant underlying disease. It is caused by elevated serum bilirubin levels in the unconjugated or conjugated form. ...Conjugated hyperbilirubinemia occurs in disorders of hepatocellular damage, such as viral and alcoholic hepa …
Jaundice in adults can be an indicator of significant underlying disease. It is caused by elevated serum bilirubin levels in the unco …
Bile Acid Metabolism in Liver Pathobiology.
Chiang JYL, Ferrell JM. Chiang JYL, et al. Gene Expr. 2018 May 18;18(2):71-87. doi: 10.3727/105221618X15156018385515. Epub 2018 Jan 11. Gene Expr. 2018. PMID: 29325602 Free PMC article. Review.
The gut-to-liver axis plays a critical role in the regulation of enterohepatic circulation of bile acids, bile acid pool size, and bile acid composition. ...Gender differences in bile acid metabolism, FXR signaling, and gut microbiota have been linked to higher prevalence …
The gut-to-liver axis plays a critical role in the regulation of enterohepatic circulation of bile acids, bile acid pool size, and bi …
Liver enzyme alteration: a guide for clinicians.
Giannini EG, Testa R, Savarino V. Giannini EG, et al. CMAJ. 2005 Feb 1;172(3):367-79. doi: 10.1503/cmaj.1040752. CMAJ. 2005. PMID: 15684121 Free PMC article. Review.
Isolated alterations of biochemical markers of liver damage in a seemingly healthy patient can present a challenge for the clinician. In this review we provide a guide to interpreting alterations to liver enzyme levels. The functional anatomy of the liver and …
Isolated alterations of biochemical markers of liver damage in a seemingly healthy patient can present a challenge for the clinician. …
Role of bile acids and their receptors in gastrointestinal and hepatic pathophysiology.
Fuchs CD, Trauner M. Fuchs CD, et al. Nat Rev Gastroenterol Hepatol. 2022 Jul;19(7):432-450. doi: 10.1038/s41575-021-00566-7. Epub 2022 Feb 14. Nat Rev Gastroenterol Hepatol. 2022. PMID: 35165436 Review.
Disrupted BA transport and homeostasis results in the development of cholestatic disorders and contributes to a wide range of liver diseases, including nonalcoholic fatty liver disease and hepatocellular and cholangiocellular carcinoma. Furtherm …
Disrupted BA transport and homeostasis results in the development of cholestatic disorders and contributes to a wide range of live
Health disparities in chronic liver disease.
Kardashian A, Serper M, Terrault N, Nephew LD. Kardashian A, et al. Hepatology. 2023 Apr 1;77(4):1382-1403. doi: 10.1002/hep.32743. Epub 2022 Sep 4. Hepatology. 2023. PMID: 35993341 Free PMC article. Review.
Highlighting health disparities, their sources, and consequences in chronic liver disease is fundamental to improving liver health outcomes. ...Herein, we review the existing literature on racial and ethnic, gender, and socioeconomic disparities in chronic …
Highlighting health disparities, their sources, and consequences in chronic liver disease is fundamental to improving liver
New Treatment Paradigms in Primary Biliary Cholangitis.
Levy C, Manns M, Hirschfield G. Levy C, et al. Clin Gastroenterol Hepatol. 2023 Jul;21(8):2076-2087. doi: 10.1016/j.cgh.2023.02.005. Epub 2023 Feb 19. Clin Gastroenterol Hepatol. 2023. PMID: 36809835 Free article. Review.
Although the female predominance, specific serum autoantibodies, immune-mediated cellular injury, as well as genetic (HLA and non-HLA) risk factors, identify PBC as autoimmune, to date treatment has focused on cholestatic consequences. Biliary epithelial homeostasis is abn …
Although the female predominance, specific serum autoantibodies, immune-mediated cellular injury, as well as genetic (HLA and non-HLA) risk …
Mechanisms of action and therapeutic efficacy of ursodeoxycholic acid in cholestatic liver disease.
Paumgartner G, Beuers U. Paumgartner G, et al. Clin Liver Dis. 2004 Feb;8(1):67-81, vi. doi: 10.1016/S1089-3261(03)00135-1. Clin Liver Dis. 2004. PMID: 15062194 Review.
Ursodeoxycholic acid (UDCA) is widely used for the treatment of cholestatic liver diseases. Multiple mechanisms of action of UDCA have been described aiming at one or more of the pathogenetic processes of cholestatic liver diseases: (1) p …
Ursodeoxycholic acid (UDCA) is widely used for the treatment of cholestatic liver diseases. Multiple mechanisms of acti …
1,476 results