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Year Number of Results
1963 1
1964 1
1986 2
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1988 27
1989 37
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1991 43
1992 59
1993 98
1994 66
1995 63
1996 70
1997 78
1998 79
1999 63
2000 69
2001 110
2002 110
2003 123
2004 108
2005 81
2006 94
2007 136
2008 118
2009 125
2010 119
2011 127
2012 122
2013 127
2014 98
2015 104
2016 116
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2018 102
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2022 68
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2024 28

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3,083 results

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Page 1
European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia.
Hochhaus A, Baccarani M, Silver RT, Schiffer C, Apperley JF, Cervantes F, Clark RE, Cortes JE, Deininger MW, Guilhot F, Hjorth-Hansen H, Hughes TP, Janssen JJWM, Kantarjian HM, Kim DW, Larson RA, Lipton JH, Mahon FX, Mayer J, Nicolini F, Niederwieser D, Pane F, Radich JP, Rea D, Richter J, Rosti G, Rousselot P, Saglio G, Saußele S, Soverini S, Steegmann JL, Turkina A, Zaritskey A, Hehlmann R. Hochhaus A, et al. Leukemia. 2020 Apr;34(4):966-984. doi: 10.1038/s41375-020-0776-2. Epub 2020 Mar 3. Leukemia. 2020. PMID: 32127639 Free PMC article. Review.
The therapeutic landscape of chronic myeloid leukemia (CML) has profoundly changed over the past 7 years. ...A change of treatment is recommended when intolerance cannot be ameliorated or when molecular milestones are not reached. Greater than 10% BCR-ABL1 …
The therapeutic landscape of chronic myeloid leukemia (CML) has profoundly changed over the past 7 years. ...A change of treat …
Management of chronic myeloid leukemia in 2023 - common ground and common sense.
Senapati J, Sasaki K, Issa GC, Lipton JH, Radich JP, Jabbour E, Kantarjian HM. Senapati J, et al. Blood Cancer J. 2023 Apr 24;13(1):58. doi: 10.1038/s41408-023-00823-9. Blood Cancer J. 2023. PMID: 37088793 Free PMC article. Review.
With the improving knowledge of CML and its management, the goals of therapy need to be revisited to ensure an optimal use of the BCR::ABL1 TKIs in the frontline and later-line therapy of CML. In the frontline therapy of CML in the chronic phase (CML-CP), ima …
With the improving knowledge of CML and its management, the goals of therapy need to be revisited to ensure an optimal use of the BCR …
Chronic Myeloid Leukemia: A Model Disease of the Past, Present and Future.
Minciacchi VR, Kumar R, Krause DS. Minciacchi VR, et al. Cells. 2021 Jan 10;10(1):117. doi: 10.3390/cells10010117. Cells. 2021. PMID: 33435150 Free PMC article. Review.
Chronic myeloid leukemia (CML) has been a "model disease" with a long history. Beginning with the first discovery of leukemia and the description of the Philadelphia Chromosome and ending with the current goal of achieving treatment-free remission after targe …
Chronic myeloid leukemia (CML) has been a "model disease" with a long history. Beginning with the first discovery of leukem …
Response and Resistance to BCR-ABL1-Targeted Therapies.
Braun TP, Eide CA, Druker BJ. Braun TP, et al. Cancer Cell. 2020 Apr 13;37(4):530-542. doi: 10.1016/j.ccell.2020.03.006. Cancer Cell. 2020. PMID: 32289275 Free PMC article. Review.
Chronic myeloid leukemia (CML), caused by constitutively active BCR-ABL1 fusion tyrosine kinase, has served as a paradigm for successful application of molecularly targeted cancer therapy. ...Some patients develop TKI resistance without known resistanc …
Chronic myeloid leukemia (CML), caused by constitutively active BCR-ABL1 fusion tyrosine kinase, has served as a …
Chronic Myeloid Leukemia: Beyond BCR-ABL1.
Zhou T, Medeiros LJ, Hu S. Zhou T, et al. Curr Hematol Malig Rep. 2018 Dec;13(6):435-445. doi: 10.1007/s11899-018-0474-6. Curr Hematol Malig Rep. 2018. PMID: 30370478 Review.
PURPOSE OF REVIEW: In this review, we emphasize up-to-date practical cytogenetic and molecular aspects of chronic myeloid leukemia (CML) and summarize current knowledge on tyrosine kinase inhibitor (TKI) resistance and treatment response monitoring of CML. ...Over t …
PURPOSE OF REVIEW: In this review, we emphasize up-to-date practical cytogenetic and molecular aspects of chronic myeloid leukemia …
Chronic Myeloid Leukemia: Modern therapies, current challenges and future directions.
Osman AEG, Deininger MW. Osman AEG, et al. Blood Rev. 2021 Sep;49:100825. doi: 10.1016/j.blre.2021.100825. Epub 2021 Mar 16. Blood Rev. 2021. PMID: 33773846 Free PMC article. Review.
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm caused by a reciprocal translocation [t(9;22)(q34;q11.2)] that leads to the fusion of ABL1 gene sequences (9q34) downstream of BCR gene sequences (22q11) and is cytogenetically visible as …
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm caused by a reciprocal translocation [t(9;22)(q34;q11.2)] that …
Molecular biology of bcr-abl1-positive chronic myeloid leukemia.
Quintás-Cardama A, Cortes J. Quintás-Cardama A, et al. Blood. 2009 Feb 19;113(8):1619-30. doi: 10.1182/blood-2008-03-144790. Epub 2008 Sep 30. Blood. 2009. PMID: 18827185 Free PMC article. Review.
Chronic myeloid leukemia (CML) has been regarded as the paradigmatic example of a malignancy defined by a unique molecular event, the BCR-ABL1 oncogene. Decades of research zeroing in on the role of BCR-ABL1 kinase in the pathogenesis of …
Chronic myeloid leukemia (CML) has been regarded as the paradigmatic example of a malignancy defined by a unique molecular eve …
Chronic myeloid leukaemia.
Cortes J, Pavlovsky C, Saußele S. Cortes J, et al. Lancet. 2021 Nov 20;398(10314):1914-1926. doi: 10.1016/S0140-6736(21)01204-6. Epub 2021 Aug 20. Lancet. 2021. PMID: 34425075 Review.
Tyrosine-kinase inhibitors have changed the natural history of chronic myeloid leukaemia in such a way that patients with adequate access to these agents, who are properly managed, and who respond well to this treatment can expect a near-normal life expectancy. ...Treatmen …
Tyrosine-kinase inhibitors have changed the natural history of chronic myeloid leukaemia in such a way that patients with adequate ac …
[Chronic myeloid leukemia - update 2020].
Heim D, Ebnöther M, Favre G. Heim D, et al. Ther Umsch. 2019;76(9):503-509. doi: 10.1024/0040-5930/a001124. Ther Umsch. 2019. PMID: 32157969 Review. German.
Chronic myeloid leukemia - update 2020 Abstract. The discovery of specific inhibitors of the BCR-ABL tyrosine kinase more than 20 years ago has revolutionized the treatment of patients with chronic myeloid leukemia (CML). ...
Chronic myeloid leukemia - update 2020 Abstract. The discovery of specific inhibitors of the BCR-ABL tyrosine ki …
Chronic myeloid leukemia: 2018 update on diagnosis, therapy and monitoring.
Jabbour E, Kantarjian H. Jabbour E, et al. Am J Hematol. 2018 Mar;93(3):442-459. doi: 10.1002/ajh.25011. Am J Hematol. 2018. PMID: 29411417 Free article. Review.
DISEASE OVERVIEW: Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm with an incidence of 1-2 cases per 100 000 adults. ...The molecular consequence of this translocation is the generation of a BCR-ABL1 fusion oncogene, which in turn trans …
DISEASE OVERVIEW: Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm with an incidence of 1-2 cases per 100 000 a …
3,083 results