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JAK2 unmutated erythrocytosis: current diagnostic approach and therapeutic views.
Gangat N, Szuber N, Pardanani A, Tefferi A. Gangat N, et al. Leukemia. 2021 Aug;35(8):2166-2181. doi: 10.1038/s41375-021-01290-6. Epub 2021 May 21. Leukemia. 2021. PMID: 34021251 Free PMC article. Review.
JAK2 unmutated or non-polycythemia vera (PV) erythrocytosis encompasses both hereditary and acquired conditions. ...Historically, management of non-PV erythrocytosis has been conflicted by unfounded concerns regarding thrombosis risk, stemming from limited phenotypic chara …
JAK2 unmutated or non-polycythemia vera (PV) erythrocytosis encompasses both hereditary and acquired conditions. ...Historically, man …
Re-evaluation of hematocrit as a determinant of thrombotic risk in erythrocytosis.
Gordeuk VR, Key NS, Prchal JT. Gordeuk VR, et al. Haematologica. 2019 Apr;104(4):653-658. doi: 10.3324/haematol.2018.210732. Epub 2019 Mar 14. Haematologica. 2019. PMID: 30872370 Free PMC article. Review.
Thrombosis is common in Chuvash erythrocytosis and polycythemia vera. Although the increased thrombotic risk is assumed to be due to the elevated hematocrit and an associated increase in blood viscosity, thrombosis does not accompany most types of erythrocytosis. We …
Thrombosis is common in Chuvash erythrocytosis and polycythemia vera. Although the increased thrombotic risk is assumed to be …
Vascular complications in Chuvash polycythemia.
Gordeuk VR, Prchal JT. Gordeuk VR, et al. Semin Thromb Hemost. 2006 Apr;32(3):289-94. doi: 10.1055/s-2006-939441. Semin Thromb Hemost. 2006. PMID: 16673284 Review.
Retrospective analyses among patients with Chuvash polycythemia have not shown benefit for therapy with phlebotomy or aspirin, but these and other modes of therapy should be studied prospectively. Further investigation of the vascular complications of Chuvash
Retrospective analyses among patients with Chuvash polycythemia have not shown benefit for therapy with phlebotomy or aspirin, …
Polycythemia and oxygen sensing.
Maran J, Prchal J. Maran J, et al. Pathol Biol (Paris). 2004 Jun;52(5):280-4. doi: 10.1016/j.patbio.2004.02.006. Pathol Biol (Paris). 2004. PMID: 15217714 Review.
These endogenous erythroid colonies (EEC) are useful in differentiating PV and secondary polycythemias. They also can differentiate PV where this feature is independent of Epo signalling from primary familial and congenital polycythemia. ...Chuvash polycyt
These endogenous erythroid colonies (EEC) are useful in differentiating PV and secondary polycythemias. They also can differentiate P …
[Inherited primitive and secondary polycythemia].
Barba T, Boileau JC, Pasquet F, Hot A, Pavic M. Barba T, et al. Rev Med Interne. 2016 Jul;37(7):460-5. doi: 10.1016/j.revmed.2015.12.022. Epub 2016 Jan 27. Rev Med Interne. 2016. PMID: 26827274 Review. French.
Myeloproliferative disorders and secondary polycythemia cover most of the polycythemia cases encountered in daily practice. Inherited polycythemias are rare entities that have to be suspected when the classical causes of acquired polycythemia have been …
Myeloproliferative disorders and secondary polycythemia cover most of the polycythemia cases encountered in daily practice. In …
Polycythemia vera and other primary polycythemias.
Prchal JT. Prchal JT. Curr Opin Hematol. 2005 Mar;12(2):112-6. doi: 10.1097/01.moh.0000154029.05396.d2. Curr Opin Hematol. 2005. PMID: 15725900 Review.
PURPOSE OF REVIEW: Diagnosis and therapy of polycythemia vera are controversial since the molecular basis of polycythemia vera remains unknown. ...Our knowledge of cellular responses to hypoxia has recently exploded and led to the elucidation of the molecular basis …
PURPOSE OF REVIEW: Diagnosis and therapy of polycythemia vera are controversial since the molecular basis of polycythemia vera …
[Inherited polycythemia].
Pavic M, Rousset H. Pavic M, et al. Rev Med Interne. 2003 Aug;24(8):514-21. doi: 10.1016/s0248-8663(03)00059-6. Rev Med Interne. 2003. PMID: 12888172 Review. French.
PURPOSE: The majority of polycythemias occurs sporadically without any other familial case. Very occasionally polycythemia finds a familial support. ...FUTURE PROSPECTS AND PROJECTS: Progressively, the part of really idiopathic polycythemias is smaller and sm …
PURPOSE: The majority of polycythemias occurs sporadically without any other familial case. Very occasionally polycythemia fin …
Lessons from familial myeloproliferative disorders.
Skoda R, Prchal JT. Skoda R, et al. Semin Hematol. 2005 Oct;42(4):266-73. doi: 10.1053/j.seminhematol.2005.08.002. Semin Hematol. 2005. PMID: 16210040 Review.
This is best documented in familial polycythemia vera (PV), which appears to be inherited as an autosomal dominant disorder with incomplete penetrance. ...Therefore, PFCP will also be discussed here, while other congenital polycythemic states such as the Chuvash
This is best documented in familial polycythemia vera (PV), which appears to be inherited as an autosomal dominant disorder with inco …
12 results