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Coenzyme Q10 for heart failure.
Al Saadi T, Assaf Y, Farwati M, Turkmani K, Al-Mouakeh A, Shebli B, Khoja M, Essali A, Madmani ME. Al Saadi T, et al. Cochrane Database Syst Rev. 2021 Feb 3;(2)(2):CD008684. doi: 10.1002/14651858.CD008684.pub3. Cochrane Database Syst Rev. 2021. PMID: 35608922 Free PMC article. Review.
It is a fat-soluble molecule that acts as an electron carrier in mitochondria, and as a coenzyme for mitochondrial enzymes. Coenzyme Q10 deficiency may be associated with a multitude of diseases, including heart failure. The severity of heart failure correlat …
It is a fat-soluble molecule that acts as an electron carrier in mitochondria, and as a coenzyme for mitochondrial enzymes. Coenzyme …
Genetic bases and clinical manifestations of coenzyme Q10 (CoQ 10) deficiency.
Desbats MA, Lunardi G, Doimo M, Trevisson E, Salviati L. Desbats MA, et al. J Inherit Metab Dis. 2015 Jan;38(1):145-56. doi: 10.1007/s10545-014-9749-9. Epub 2014 Aug 5. J Inherit Metab Dis. 2015. PMID: 25091424 Review.
CoQ(10) deficiency can also be observed in patients with defects unrelated to CoQ(10) biosynthesis, such as RC defects, multiple acyl-CoA dehydrogenase deficiency, and ataxia and oculomotor apraxia.Patients with both primary and secondary deficiencies benefit from high-dos …
CoQ(10) deficiency can also be observed in patients with defects unrelated to CoQ(10) biosynthesis, such as RC defects, multiple acyl-CoA de …
[Primary coenzyme Q10 deficiency-7: a case report and literature review].
Chen XR, Xu JP, Yao YH. Chen XR, et al. Zhonghua Er Ke Za Zhi. 2020 Nov 2;58(11):928-932. doi: 10.3760/cma.j.cn112140-20200610-00601. Zhonghua Er Ke Za Zhi. 2020. PMID: 33120466 Review. Chinese.
Objective: To explore the clinical characteristics and gene variation of primary coenzyme Q10 deficiency-7 (COQ10D7) in children. Methods: Clinical data and genetic tests results of a COQ10D7 child caused by coenzyme Q4 (COQ4) gene variation at the Fir …
Objective: To explore the clinical characteristics and gene variation of primary coenzyme Q10 deficiency-7 (COQ1 …
Two Turkish patients with Primary Coenzyme Q10 Deficiency-7: case report and literature review.
Sonuç Kartal G, Koç Yekedüz M, Köse E, Eminoğlu FT. Sonuç Kartal G, et al. J Pediatr Endocrinol Metab. 2024 Feb 2;37(3):260-270. doi: 10.1515/jpem-2023-0490. Print 2024 Mar 25. J Pediatr Endocrinol Metab. 2024. PMID: 38353291 Review.
OBJECTIVES: Primary Coenzyme Q10 Deficiency-7 (OMIM 616276) results from bi-allelic pathogenic variants in the COQ4 gene. ...Laboratory findings were within normal limits, while a whole exome sequencing analysis revealed a homozygous variant previously …
OBJECTIVES: Primary Coenzyme Q10 Deficiency-7 (OMIM 616276) results from bi-allelic pathogenic variants in the C …
The Roles of Coenzyme Q in Disease: Direct and Indirect Involvement in Cellular Functions.
Pallotti F, Bergamini C, Lamperti C, Fato R. Pallotti F, et al. Int J Mol Sci. 2021 Dec 23;23(1):128. doi: 10.3390/ijms23010128. Int J Mol Sci. 2021. PMID: 35008564 Free PMC article. Review.
The complete knowledge of the various cellular CoQ functions is essential to provide a rational basis for its possible therapeutic use, not only in diseases characterized by primary CoQ deficiency, but also in large number of diseases in which its secondary deficiency has …
The complete knowledge of the various cellular CoQ functions is essential to provide a rational basis for its possible therapeutic use, not …
Coenzyme Q10 for heart failure.
Madmani ME, Yusuf Solaiman A, Tamr Agha K, Madmani Y, Shahrour Y, Essali A, Kadro W. Madmani ME, et al. Cochrane Database Syst Rev. 2014 Jun 2;(6):CD008684. doi: 10.1002/14651858.CD008684.pub2. Cochrane Database Syst Rev. 2014. PMID: 24049047 Updated. Review.
It is a fat-soluble molecule that acts as an electron carrier in mitochondria and as a coenzyme for mitochondrial enzymes. Coenzyme Q10 deficiency may be associated with a multitude of diseases including heart failure. The severity of heart failure correlates …
It is a fat-soluble molecule that acts as an electron carrier in mitochondria and as a coenzyme for mitochondrial enzymes. Coenzyme …
[Clinical analysis of one infantile nephrotic syndrome caused by COQ2 gene mutation and literature review].
Xu K, Mao XY, Yao Y, Cheng H, Zhang XJ. Xu K, et al. Zhonghua Er Ke Za Zhi. 2018 Sep 2;56(9):662-666. doi: 10.3760/cma.j.issn.0578-1310.2018.09.006. Zhonghua Er Ke Za Zhi. 2018. PMID: 30180404 Review. Chinese.
Related literature retrieved from PubMed, CNKI and Wanfang databases were searched to date (up to July 2018) with "COQ2 gene" or "primary coenzyme Q10 deficiency" and "nephrotic syndrome" or "nephropathy" as key words. ...Primary CoQ10 deficienc …
Related literature retrieved from PubMed, CNKI and Wanfang databases were searched to date (up to July 2018) with "COQ2 gene" or "primary …