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Coenzyme Q10 for heart failure.
Al Saadi T, Assaf Y, Farwati M, Turkmani K, Al-Mouakeh A, Shebli B, Khoja M, Essali A, Madmani ME. Al Saadi T, et al. Cochrane Database Syst Rev. 2021 Feb 3;(2)(2):CD008684. doi: 10.1002/14651858.CD008684.pub3. Cochrane Database Syst Rev. 2021. PMID: 35608922 Free PMC article. Review.
It is a fat-soluble molecule that acts as an electron carrier in mitochondria, and as a coenzyme for mitochondrial enzymes. Coenzyme Q10 deficiency may be associated with a multitude of diseases, including heart failure. The severity of heart failure correlat …
It is a fat-soluble molecule that acts as an electron carrier in mitochondria, and as a coenzyme for mitochondrial enzymes. Coenzyme …
Primary and secondary coenzyme Q10 deficiency: the role of therapeutic supplementation.
Potgieter M, Pretorius E, Pepper MS. Potgieter M, et al. Nutr Rev. 2013 Mar;71(3):180-8. doi: 10.1111/nure.12011. Epub 2013 Jan 30. Nutr Rev. 2013. PMID: 23452285 Review.
A deficiency in either its bioavailability or its biosynthesis can lead to one of several disease states. Primary deficiency has been well described and results from mutations in genes involved in CoQ10 biosynthesis. ...However, CoQ10 is not routinely prescribed in clinica …
A deficiency in either its bioavailability or its biosynthesis can lead to one of several disease states. Primary deficiency has been …
Genetic bases and clinical manifestations of coenzyme Q10 (CoQ 10) deficiency.
Desbats MA, Lunardi G, Doimo M, Trevisson E, Salviati L. Desbats MA, et al. J Inherit Metab Dis. 2015 Jan;38(1):145-56. doi: 10.1007/s10545-014-9749-9. Epub 2014 Aug 5. J Inherit Metab Dis. 2015. PMID: 25091424 Review.
CoQ(10) deficiency can also be observed in patients with defects unrelated to CoQ(10) biosynthesis, such as RC defects, multiple acyl-CoA dehydrogenase deficiency, and ataxia and oculomotor apraxia.Patients with both primary and secondary deficiencies benefit from high-dos …
CoQ(10) deficiency can also be observed in patients with defects unrelated to CoQ(10) biosynthesis, such as RC defects, multiple acyl-CoA de …
Clinical syndromes associated with Coenzyme Q10 deficiency.
Alcázar-Fabra M, Trevisson E, Brea-Calvo G. Alcázar-Fabra M, et al. Essays Biochem. 2018 Jul 20;62(3):377-398. doi: 10.1042/EBC20170107. Print 2018 Jul 20. Essays Biochem. 2018. PMID: 30030365 Review.
Primary Coenzyme Q deficiencies represent a group of rare conditions caused by mutations in one of the genes required in its biosynthetic pathway at the enzymatic or regulatory level. ...Here, we present an updated and comprehensive review of the clinical manifestations as …
Primary Coenzyme Q deficiencies represent a group of rare conditions caused by mutations in one of the genes required in its biosynth …
Two Turkish patients with Primary Coenzyme Q10 Deficiency-7: case report and literature review.
Sonuç Kartal G, Koç Yekedüz M, Köse E, Eminoğlu FT. Sonuç Kartal G, et al. J Pediatr Endocrinol Metab. 2024 Feb 2;37(3):260-270. doi: 10.1515/jpem-2023-0490. Print 2024 Mar 25. J Pediatr Endocrinol Metab. 2024. PMID: 38353291 Review.
OBJECTIVES: Primary Coenzyme Q10 Deficiency-7 (OMIM 616276) results from bi-allelic pathogenic variants in the COQ4 gene. ...Laboratory findings were within normal limits, while a whole exome sequencing analysis revealed a homozygous variant previously …
OBJECTIVES: Primary Coenzyme Q10 Deficiency-7 (OMIM 616276) results from bi-allelic pathogenic variants in the C …
Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension.
Ho MJ, Bellusci A, Wright JM. Ho MJ, et al. Cochrane Database Syst Rev. 2009 Oct 7;(4):CD007435. doi: 10.1002/14651858.CD007435.pub2. Cochrane Database Syst Rev. 2009. PMID: 19821418 Updated. Review.
BACKGROUND: Studies have shown that coenzyme Q10 deficiency is associated with cardiovascular disease. ...SELECTION CRITERIA: Double-blind, randomized, placebo-controlled parallel or crossover trials evaluating the BP lowering efficacy of coenzyme Q10 for a d …
BACKGROUND: Studies have shown that coenzyme Q10 deficiency is associated with cardiovascular disease. ...SELECTION CRI …
Coenzyme Q10 for heart failure.
Madmani ME, Yusuf Solaiman A, Tamr Agha K, Madmani Y, Shahrour Y, Essali A, Kadro W. Madmani ME, et al. Cochrane Database Syst Rev. 2014 Jun 2;(6):CD008684. doi: 10.1002/14651858.CD008684.pub2. Cochrane Database Syst Rev. 2014. PMID: 24049047 Updated. Review.
It is a fat-soluble molecule that acts as an electron carrier in mitochondria and as a coenzyme for mitochondrial enzymes. Coenzyme Q10 deficiency may be associated with a multitude of diseases including heart failure. The severity of heart failure correlates …
It is a fat-soluble molecule that acts as an electron carrier in mitochondria and as a coenzyme for mitochondrial enzymes. Coenzyme …