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2025

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Year Number of Results
2008 2
2011 1
2015 1
2016 2
2017 1
2018 1
2019 3
2020 2
2021 1
2022 2
2023 1
2024 3
2025 0

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19 results

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Page 1
Biological basis and treatment of frailty and sarcopenia.
Sato R, Vatic M, Peixoto da Fonseca GW, Anker SD, von Haehling S. Sato R, et al. Cardiovasc Res. 2024 Jul 31;120(9):982-998. doi: 10.1093/cvr/cvae073. Cardiovasc Res. 2024. PMID: 38828887 Review.
The biological mechanisms of frailty and sarcopenia are multifactorial, complex, and not yet fully elucidated, ranging from DNA damage, proteostasis impairment, and epigenetic changes to mitochondrial dysfunction, cellular senescence, and environmental factors, many of whi …
The biological mechanisms of frailty and sarcopenia are multifactorial, complex, and not yet fully elucidated, ranging from DNA damage, prot …
An Overview of Biochemical Genetics.
Sharer JD. Sharer JD. Curr Protoc Hum Genet. 2016 Apr 1;89:17.1.1-17.1.16. doi: 10.1002/0471142905.hg1701s89. Curr Protoc Hum Genet. 2016. PMID: 27037486 Review.
Biochemical genetics focuses on the pathophysiology, diagnosis, and treatment of inherited metabolic disorders. While individually rare, the combined incidence of these diseases makes them a significant source of morbidity and mortality, particularly among infants a …
Biochemical genetics focuses on the pathophysiology, diagnosis, and treatment of inherited metabolic disorders. While individually rare, the …
Anabolic Strategies for ICU-Acquired Weakness. What Can We Learn from Bodybuilders?
Tarnawski J, Czub M, Dymecki M, Sunil M, Folwarski M. Tarnawski J, et al. Nutrients. 2024 Jun 25;16(13):2011. doi: 10.3390/nu16132011. Nutrients. 2024. PMID: 38999759 Free PMC article. Review.
ICUAW is a common complication affecting approximately 40% of critically ill patients, often leading to long-term functional disability. ICUAW comprises critical illness polyneuropathy, critical illness myopathy, or a combination of both, such as critical illness po …
ICUAW is a common complication affecting approximately 40% of critically ill patients, often leading to long-term functional disabili …
Endothelial Activation and Oxidative Stress in Neurovascular Defects of the Retina.
Lenin R, Thomas SM, Gangaraju R. Lenin R, et al. Curr Pharm Des. 2018;24(40):4742-4754. doi: 10.2174/1381612825666190115122622. Curr Pharm Des. 2018. PMID: 30644342 Review.
BACKGROUND: The eye is considered as a window of the disease, and a better understanding of neurodegenerative changes in the eye may help diagnose and manage neurodegenerative diseases including the diseases of brain, heart, kidney and liver. In the eye, the blood r …
BACKGROUND: The eye is considered as a window of the disease, and a better understanding of neurodegenerative changes in the eye may help di …
Targeting autophagy, oxidative stress, and ER stress for neurodegenerative disease treatment.
Esmaeili Y, Yarjanli Z, Pakniya F, Bidram E, Łos MJ, Eshraghi M, Klionsky DJ, Ghavami S, Zarrabi A. Esmaeili Y, et al. J Control Release. 2022 May;345:147-175. doi: 10.1016/j.jconrel.2022.03.001. Epub 2022 Mar 3. J Control Release. 2022. PMID: 35248646 Review.
Protein homeostasis is a vital process for cell function and, therefore, disruption of the molecular mechanisms involved in this process, such as autophagy, may contribute to neurodegenerative diseases (NDs). Apart from autophagy disruption, excess oxidative stress …
Protein homeostasis is a vital process for cell function and, therefore, disruption of the molecular mechanisms involved in this process, su …
Cachexia and sarcopenia: mechanisms and potential targets for intervention.
Argilés JM, Busquets S, Stemmler B, López-Soriano FJ. Argilés JM, et al. Curr Opin Pharmacol. 2015 Jun;22:100-6. doi: 10.1016/j.coph.2015.04.003. Epub 2015 May 14. Curr Opin Pharmacol. 2015. PMID: 25974750 Review.
Skeletal muscle tissue represents more than 40% of body weight and seems to be one of the main tissues involved in the wasting that occurs during cachexia. ...Oxidative pathways are also altered in skeletal muscle during muscle wasting and this seems to be a consequ …
Skeletal muscle tissue represents more than 40% of body weight and seems to be one of the main tissues involved in the wasting that o …
Pharmacological treatments for Friedreich ataxia.
Kearney M, Orrell RW, Fahey M, Brassington R, Pandolfo M. Kearney M, et al. Cochrane Database Syst Rev. 2016 Aug 30;2016(8):CD007791. doi: 10.1002/14651858.CD007791.pub4. Cochrane Database Syst Rev. 2016. PMID: 27572719 Free PMC article. Review.
MAIN RESULTS: We identified more than 12 studies that used antioxidants in the treatment of Friedreich ataxia, but only two small RCTs, with a combined total of 72 participants, both fulfilled the selection criteria for this review and published results. ...AUTHORS' CONCLU …
MAIN RESULTS: We identified more than 12 studies that used antioxidants in the treatment of Friedreich ataxia, but only two small RCTs, with …
Liver involvement in urea cycle disorders: a review of the literature.
Bigot A, Tchan MC, Thoreau B, Blasco H, Maillot F. Bigot A, et al. J Inherit Metab Dis. 2017 Nov;40(6):757-769. doi: 10.1007/s10545-017-0088-5. Epub 2017 Sep 12. J Inherit Metab Dis. 2017. PMID: 28900784 Review.
UCDs may differ in liver involvement according to the enzymatic deficiency. Ornithine transcarbamylase deficiency may be associated more with acute liver failure and argininosuccinic aciduria with chronic liver failure and cirrhosis. Direct toxicity of metabolites, …
UCDs may differ in liver involvement according to the enzymatic deficiency. Ornithine transcarbamylase deficiency may be assoc …
The Aging Thyroid: A Reappraisal Within the Geroscience Integrated Perspective.
Franceschi C, Ostan R, Mariotti S, Monti D, Vitale G. Franceschi C, et al. Endocr Rev. 2019 Oct 1;40(5):1250-1270. doi: 10.1210/er.2018-00170. Endocr Rev. 2019. PMID: 31074798 Free article. Review.
The thyroid plays a crucial and pervasive role in physiology (metabolism, thermogenesis, and immunity, among others) and its aging and related changes in thyroid hormone production contribute to the common occurrence of thyroid diseases in elderly and to age-associated cha …
The thyroid plays a crucial and pervasive role in physiology (metabolism, thermogenesis, and immunity, among others) and its aging and relat …
Photobiomodulation Therapy on the Treatment of Insulin Resistance: A Narrative Review.
Magalhães FC, Ferraresi C. Magalhães FC, et al. Photobiomodul Photomed Laser Surg. 2022 Sep;40(9):597-603. doi: 10.1089/photob.2022.0031. Epub 2022 Aug 30. Photobiomodul Photomed Laser Surg. 2022. PMID: 36040371 Review.
Photobiomodulation therapy (PBMT) is another noninvasive and nonpharmacological therapy, which produces positive effects on mitochondrial metabolism, oxidative stress, and inflammation generally linked to IR and DM2 and may improve or attenuate the severity of these …
Photobiomodulation therapy (PBMT) is another noninvasive and nonpharmacological therapy, which produces positive effects on mitochondrial
19 results