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Page 1
Lipodystrophy Syndromes.
Hussain I, Garg A. Hussain I, et al. Endocrinol Metab Clin North Am. 2016 Dec;45(4):783-797. doi: 10.1016/j.ecl.2016.06.012. Epub 2016 Oct 6. Endocrinol Metab Clin North Am. 2016. PMID: 27823605 Free PMC article. Review.
The two most common genetic varieties include congenital generalized lipodystrophy and familial partial lipodystrophy; the two most common acquired varieties include acquired generalized lipodystrophy and acquired partial lipodystrophy
The two most common genetic varieties include congenital generalized lipodystrophy and familial partial lipodystroph
Lipodystrophy for the Diabetologist-What to Look For.
Patni N, Garg A. Patni N, et al. Curr Diab Rep. 2022 Sep;22(9):461-470. doi: 10.1007/s11892-022-01485-w. Epub 2022 Jul 11. Curr Diab Rep. 2022. PMID: 35821558 Free PMC article. Review.
In this review, we discuss the various subtypes and when to suspect and how to diagnose lipodystrophy. RECENT FINDINGS: The four major subtypes are autosomal recessive, congenital generalized lipodystrophy (CGL); acquired generalized lipodyst
In this review, we discuss the various subtypes and when to suspect and how to diagnose lipodystrophy. RECENT FINDINGS: The four majo …
Diagnosis and treatment of lipodystrophy: a step-by-step approach.
Araújo-Vilar D, Santini F. Araújo-Vilar D, et al. J Endocrinol Invest. 2019 Jan;42(1):61-73. doi: 10.1007/s40618-018-0887-z. Epub 2018 Apr 27. J Endocrinol Invest. 2019. PMID: 29704234 Free PMC article. Review.
RESULTS: Lipodystrophy is classified as genetic or acquired and by the distribution of fat loss, which can be generalized or partial. ...Leptin replacement therapy (metreleptin) has been found to improve metabolic parameters in many patients with lipodystrophy
RESULTS: Lipodystrophy is classified as genetic or acquired and by the distribution of fat loss, which can be generalized or p …
Generalized lipoatrophy syndromes.
Sorkina E, Chichkova V. Sorkina E, et al. Presse Med. 2021 Nov;50(3):104075. doi: 10.1016/j.lpm.2021.104075. Epub 2021 Sep 22. Presse Med. 2021. PMID: 34562560 Review.
Generalized lipodystrophy (GL) syndromes are a group of rare heterogenous disorders, characterized by total subcutaneous fat loss. ...In this review we aimed to summarize the information on all forms of generalized lipodystrophy, especially the ones of
Generalized lipodystrophy (GL) syndromes are a group of rare heterogenous disorders, characterized by total subcutaneous fat l
Lipodystrophies in Children.
Mainieri F, Chiarelli F. Mainieri F, et al. Horm Res Paediatr. 2022;95(4):305-320. doi: 10.1159/000522620. Epub 2022 Feb 21. Horm Res Paediatr. 2022. PMID: 35189617 Free article. Review.
BACKGROUND: Lipodystrophy includes a wide group of diseases characterized by reduction, absence, or altered distribution of adipose tissue. Lipodystrophies are classified into generalized or partial, according to the fat distribution, and congenital or acquir …
BACKGROUND: Lipodystrophy includes a wide group of diseases characterized by reduction, absence, or altered distribution of adipose t …
Lipodystrophies.
Garg A. Garg A. Am J Med. 2000 Feb;108(2):143-52. doi: 10.1016/s0002-9343(99)00414-3. Am J Med. 2000. PMID: 11126308 Review.
The main subtypes of familial lipodystrophies are congenital generalized lipodystrophy, an autosomal recessive disorder characterized by near complete lack of metabolically active adipose tissue from birth, and familial partial lipodystrophy, Dunnigan …
The main subtypes of familial lipodystrophies are congenital generalized lipodystrophy, an autosomal recessive disorder …
Leptin in congenital and HIV-associated lipodystrophy.
Tsoukas MA, Farr OM, Mantzoros CS. Tsoukas MA, et al. Metabolism. 2015 Jan;64(1):47-59. doi: 10.1016/j.metabol.2014.07.017. Epub 2014 Aug 12. Metabolism. 2015. PMID: 25267014 Review.
Pronounced complications of insulin resistance, dyslipidemia and fatty liver are observed in patients suffering from congenital or acquired generalized lipodystrophy while somewhat less pronounced abnormalities are associated with human immunodeficiency virus …
Pronounced complications of insulin resistance, dyslipidemia and fatty liver are observed in patients suffering from congenital or ac …
Congenital lipodystrophies and dyslipidemias.
Prieur X, Le May C, Magré J, Cariou B. Prieur X, et al. Curr Atheroscler Rep. 2014 Sep;16(9):437. doi: 10.1007/s11883-014-0437-x. Curr Atheroscler Rep. 2014. PMID: 25047893 Review.
One key metabolic feature of patients with congenital inherited lipodystrophy is hypertriglyceridemia. The precise mechanisms by which the lack of adipose tissue causes dyslipidemia remain largely unknown. In recent years, new insights have arisen from data obtained …
One key metabolic feature of patients with congenital inherited lipodystrophy is hypertriglyceridemia. The precise mechanisms …
Lipodystrophies-Disorders of the Fatty Tissue.
Knebel B, Müller-Wieland D, Kotzka J. Knebel B, et al. Int J Mol Sci. 2020 Nov 20;21(22):8778. doi: 10.3390/ijms21228778. Int J Mol Sci. 2020. PMID: 33233602 Free PMC article. Review.
A simple clinical classification of lipodystrophies is based on congenital vs. acquired and generalized vs. partial disturbance of fat distribution. Complications in patients with lipodystrophy depend on the clinical manifestations. ...The combination of seve …
A simple clinical classification of lipodystrophies is based on congenital vs. acquired and generalized vs. partial disturbanc …
Metreleptin and generalized lipodystrophy and evolving therapeutic perspectives.
Tchang BG, Shukla AP, Aronne LJ. Tchang BG, et al. Expert Opin Biol Ther. 2015 Jul;15(7):1061-75. doi: 10.1517/14712598.2015.1052789. Expert Opin Biol Ther. 2015. PMID: 26063386 Review.
INTRODUCTION: Metreleptin was recently approved by the Food and Drug Administration for the treatment of generalized lipodystrophy, a condition characterized by leptin deficiency. Its efficacy as hormone replacement therapy suggests broader applications in diseases …
INTRODUCTION: Metreleptin was recently approved by the Food and Drug Administration for the treatment of generalized lipodystrophy
79 results