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1994
2025

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 1
1995 4
1996 2
1997 4
1998 3
1999 6
2000 9
2001 5
2002 3
2003 8
2004 6
2005 7
2006 3
2007 4
2008 9
2009 7
2010 2
2011 4
2012 2
2013 4
2014 8
2015 1
2016 6
2017 5
2018 3
2019 3
2020 5
2021 8
2022 5
2023 5
2024 1
2025 0

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137 results

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Page 1
Mitochondria during T cell aging.
Escrig-Larena JI, Delgado-Pulido S, Mittelbrunn M. Escrig-Larena JI, et al. Semin Immunol. 2023 Sep;69:101808. doi: 10.1016/j.smim.2023.101808. Epub 2023 Jul 18. Semin Immunol. 2023. PMID: 37473558 Free article. Review.
It is characterized by alterations of the mitochondrial DNA, reduced respiratory capacity, decreased mitochondrial membrane potential and increased reactive oxygen species production. These primary alterations disrupt other interconnected and important mitochondrial-relate …
It is characterized by alterations of the mitochondrial DNA, reduced respiratory capacity, decreased mitochondrial membrane potential …
The role of cytokines in T-cell memory in health and disease.
Raeber ME, Zurbuchen Y, Impellizzieri D, Boyman O. Raeber ME, et al. Immunol Rev. 2018 May;283(1):176-193. doi: 10.1111/imr.12644. Immunol Rev. 2018. PMID: 29664568 Free article. Review.
Upon stimulation with their cognate antigen, naive T cells undergo proliferation and differentiation into effector cells, followed by apoptosis or survival as precursors of long-lived memory cells. These phases of a T-cell response and the ensuing maintenance of memory T c …
Upon stimulation with their cognate antigen, naive T cells undergo proliferation and differentiation into effector cells, followed by apo
IMMUNE CELL PHENOTYPE AND FUNCTION IN SEPSIS.
Rimmelé T, Payen D, Cantaluppi V, Marshall J, Gomez H, Gomez A, Murray P, Kellum JA; ADQI XIV Workgroup. Rimmelé T, et al. Shock. 2016 Mar;45(3):282-91. doi: 10.1097/SHK.0000000000000495. Shock. 2016. PMID: 26529661 Free PMC article. Review.
Regarding adaptive immunity, sepsis-induced apoptosis leads to lymphopenia in patients with septic shock and it involves all types of T cells (CD4, CD8, and Natural Killer) except T regulatory cells, thus favoring immunosuppression. ...
Regarding adaptive immunity, sepsis-induced apoptosis leads to lymphopenia in patients with septic shock and it involves all t …
Lymphocyte-mediated cytotoxicity.
Russell JH, Ley TJ. Russell JH, et al. Annu Rev Immunol. 2002;20:323-70. doi: 10.1146/annurev.immunol.20.100201.131730. Epub 2001 Oct 4. Annu Rev Immunol. 2002. PMID: 11861606 Review.
The granule exocytosis pathway utilizes perforin to traffic the granzymes to appropriate locations in target cells, where they cleave critical substrates that initiate DNA fragmentation and apoptosis; granzymes A and B induce death via alternate, nonoverlapping pathways. T …
The granule exocytosis pathway utilizes perforin to traffic the granzymes to appropriate locations in target cells, where they cleave critic …
Exercise-induced leukocyte apoptosis.
Krüger K, Mooren FC. Krüger K, et al. Exerc Immunol Rev. 2014;20:117-34. Exerc Immunol Rev. 2014. PMID: 24974724 Free article. Review.
It can be assumed, that lymphocytopenia can be attributed at least partially to an enhanced lymphocyte apoptosis. In contrast, regulation of neutrophil apoptosis after exercise remains controversial since studies demonstrated both an up-regulation as well as …
It can be assumed, that lymphocytopenia can be attributed at least partially to an enhanced lymphocyte apoptosis. In contrast, …
An Overview on Genistein and its Various Formulations.
Jaiswal N, Akhtar J, Singh SP; Badruddeen; Ahsan F. Jaiswal N, et al. Drug Res (Stuttg). 2019 Jun;69(6):305-313. doi: 10.1055/a-0797-3657. Epub 2018 Dec 5. Drug Res (Stuttg). 2019. PMID: 30517965 Free article. Review.
Genistein is the natural isoflavone and a phytoestrogen with a broad range of pharmacological properties, such as tyrosine and topoisomerase inhibition. It also induces apoptosis and cell proliferation inhibition, differentiates cancer cells. Added health benefits include …
Genistein is the natural isoflavone and a phytoestrogen with a broad range of pharmacological properties, such as tyrosine and topoisomerase …
Lymphopenia in sepsis-an acquired immunodeficiency?
Finfer S, Venkatesh B, Hotchkiss RS, Sasson SC. Finfer S, et al. Immunol Cell Biol. 2023 Jul;101(6):535-544. doi: 10.1111/imcb.12611. Epub 2022 Dec 16. Immunol Cell Biol. 2023. PMID: 36468797 Review.
In COVID-19, the presence of lymphopenia correlates with intensive care unit admission, acute respiratory distress syndrome and death. The mechanisms underpinning lymphopenic sepsis remain unknown, and while high rates of lymphocyte apoptosis have been implic …
In COVID-19, the presence of lymphopenia correlates with intensive care unit admission, acute respiratory distress syndrome and death …
Apoptosis-induced lymphopenia in sepsis and other severe injuries.
Girardot T, Rimmelé T, Venet F, Monneret G. Girardot T, et al. Apoptosis. 2017 Feb;22(2):295-305. doi: 10.1007/s10495-016-1325-3. Apoptosis. 2017. PMID: 27812767 Review.
Indeed, apoptosis-induced lymphopenia duration and depth have been associated with higher risk of infection and mortality in various clinical settings. ...After briefly describing the apoptosis process in physiology and during severe injuries, we will explore …
Indeed, apoptosis-induced lymphopenia duration and depth have been associated with higher risk of infection and mortality in v …
The Calm after the Storm: Implications of Sepsis Immunoparalysis on Host Immunity.
Silva EE, Skon-Hegg C, Badovinac VP, Griffith TS. Silva EE, et al. J Immunol. 2023 Sep 1;211(5):711-719. doi: 10.4049/jimmunol.2300171. J Immunol. 2023. PMID: 37603859 Free PMC article. Review.
The immunological hallmarks of sepsis include the inflammation-mediated cytokine storm, apoptosis-driven lymphopenia, and prolonged immunoparalysis. Although early clinical efforts were focused on increasing the survival of patients through the first phase, studies …
The immunological hallmarks of sepsis include the inflammation-mediated cytokine storm, apoptosis-driven lymphopenia, and prol …
Mitochondria as a key player in systemic lupus erythematosus.
Quintero-González DC, Muñoz-Urbano M, Vásquez G. Quintero-González DC, et al. Autoimmunity. 2022 Dec;55(8):497-505. doi: 10.1080/08916934.2022.2112181. Epub 2022 Aug 17. Autoimmunity. 2022. PMID: 35978536 Free article. Review.
Furthermore, increased oxidative stress contributes to post-translational changes in different molecules (proteins, nucleic acids, and lipids), release of oxidized mitochondrial DNA through a pore of voltage-dependent anion channel oligomers, and spontaneous mitochondrial antivir …
Furthermore, increased oxidative stress contributes to post-translational changes in different molecules (proteins, nucleic acids, and lipid …
137 results