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1963
2025

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 8
1964 10
1965 6
1966 10
1967 17
1968 30
1969 31
1970 58
1971 50
1972 86
1973 87
1974 72
1975 73
1976 68
1977 54
1978 46
1979 51
1980 57
1981 68
1982 70
1983 82
1984 89
1985 108
1986 109
1987 65
1988 97
1989 122
1990 139
1991 144
1992 183
1993 235
1994 232
1995 264
1996 253
1997 281
1998 373
1999 393
2000 464
2001 487
2002 521
2003 536
2004 553
2005 591
2006 691
2007 669
2008 610
2009 610
2010 681
2011 760
2012 755
2013 821
2014 770
2015 687
2016 749
2017 727
2018 703
2019 742
2020 834
2021 805
2022 602
2023 556
2024 671
2025 45

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18,905 results

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Reprogramming of glucose, fatty acid and amino acid metabolism for cancer progression.
Li Z, Zhang H. Li Z, et al. Cell Mol Life Sci. 2016 Jan;73(2):377-92. doi: 10.1007/s00018-015-2070-4. Epub 2015 Oct 23. Cell Mol Life Sci. 2016. PMID: 26499846 Free PMC article. Review.
In addition, deregulated anabolism/catabolism of fatty acids and amino acids, especially glutamine, serine and glycine, have been identified to function as metabolic regulators in supporting cancer cell growth. ...Here we review recent findings related …
In addition, deregulated anabolism/catabolism of fatty acids and amino acids, especially glutamine, serine and glycine, …
Amino acids: metabolism, functions, and nutrition.
Wu G. Wu G. Amino Acids. 2009 May;37(1):1-17. doi: 10.1007/s00726-009-0269-0. Epub 2009 Mar 20. Amino Acids. 2009. PMID: 19301095 Review.
Recent years have witnessed the discovery that amino acids (AA) are not only cell signaling molecules but are also regulators of gene expression and the protein phosphorylation cascade. ...However, elevated levels of AA and their products (e.g., ammonia, homocystein …
Recent years have witnessed the discovery that amino acids (AA) are not only cell signaling molecules but are also regulators …
Amino acid metabolism in health and disease.
Ling ZN, Jiang YF, Ru JN, Lu JH, Ding B, Wu J. Ling ZN, et al. Signal Transduct Target Ther. 2023 Sep 13;8(1):345. doi: 10.1038/s41392-023-01569-3. Signal Transduct Target Ther. 2023. PMID: 37699892 Free PMC article. Review.
Amino acid metabolism disorders have been linked with a number of pathological conditions, including metabolic diseases, cardiovascular diseases, immune diseases, and cancer. ...Therefore, studying amino acid metabolism asso
Amino acid metabolism disorders have been linked with a number of pathological conditions, including metaboli
Metabolomics and lipidomics in NAFLD: biomarkers and non-invasive diagnostic tests.
Masoodi M, Gastaldelli A, Hyötyläinen T, Arretxe E, Alonso C, Gaggini M, Brosnan J, Anstee QM, Millet O, Ortiz P, Mato JM, Dufour JF, Orešič M. Masoodi M, et al. Nat Rev Gastroenterol Hepatol. 2021 Dec;18(12):835-856. doi: 10.1038/s41575-021-00502-9. Epub 2021 Sep 10. Nat Rev Gastroenterol Hepatol. 2021. PMID: 34508238 Review.
Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases worldwide and is often associated with aspects of metabolic syndrome. ...Overall, the studies demonstrated alterations in amino acid metabolism and several aspects …
Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases worldwide and is often associated with aspects of …
Metabolomics in rheumatoid arthritis: Advances and review.
Xu L, Chang C, Jiang P, Wei K, Zhang R, Jin Y, Zhao J, Xu L, Shi Y, Guo S, He D. Xu L, et al. Front Immunol. 2022 Aug 11;13:961708. doi: 10.3389/fimmu.2022.961708. eCollection 2022. Front Immunol. 2022. PMID: 36032122 Free PMC article. Review.
Rheumatoid arthritis (RA) is an autoimmune disease accompanied by metabolic alterations. The metabolic profiles of patients with RA can be determined using targeted and non-targeted metabolomics technology. Metabolic changes in glucose, lipid, and a
Rheumatoid arthritis (RA) is an autoimmune disease accompanied by metabolic alterations. The metabolic profiles of pati …
Branched Chain Amino Acids: Beyond Nutrition Metabolism.
Nie C, He T, Zhang W, Zhang G, Ma X. Nie C, et al. Int J Mol Sci. 2018 Mar 23;19(4):954. doi: 10.3390/ijms19040954. Int J Mol Sci. 2018. PMID: 29570613 Free PMC article. Review.
Branched chain amino acids (BCAAs), including leucine (Leu), isoleucine (Ile), and valine (Val), play critical roles in the regulation of energy homeostasis, nutrition metabolism, gut health, immunity and disease in humans and animals. As the most abun …
Branched chain amino acids (BCAAs), including leucine (Leu), isoleucine (Ile), and valine (Val), play critical roles in the re …
Amino acid transporters revisited: New views in health and disease.
Kandasamy P, Gyimesi G, Kanai Y, Hediger MA. Kandasamy P, et al. Trends Biochem Sci. 2018 Oct;43(10):752-789. doi: 10.1016/j.tibs.2018.05.003. Epub 2018 Aug 31. Trends Biochem Sci. 2018. PMID: 30177408 Review.
Amino acid transporters (AATs) are membrane-bound transport proteins that mediate transfer of amino acids into and out of cells or cellular organelles. ...In cancer cells and diabetes, dysregulation of AATs leads to metabolic reprogramming, whic
Amino acid transporters (AATs) are membrane-bound transport proteins that mediate transfer of amino acids into a
Tryptophan Metabolism in Depression: A Narrative Review with a Focus on Serotonin and Kynurenine Pathways.
Correia AS, Vale N. Correia AS, et al. Int J Mol Sci. 2022 Jul 31;23(15):8493. doi: 10.3390/ijms23158493. Int J Mol Sci. 2022. PMID: 35955633 Free PMC article. Review.
There is a high need for the development of new therapies and gaining new insights into this disease is urgent. One important player in depression is the amino acid tryptophan. This amino acid can be metabolized in two important pathways …
There is a high need for the development of new therapies and gaining new insights into this disease is urgent. One important player …
Histidine in Health and Disease: Metabolism, Physiological Importance, and Use as a Supplement.
Holeček M. Holeček M. Nutrients. 2020 Mar 22;12(3):848. doi: 10.3390/nu12030848. Nutrients. 2020. PMID: 32235743 Free PMC article. Review.
L-histidine (HIS) is an essential amino acid with unique roles in proton buffering, metal ion chelation, scavenging of reactive oxygen and nitrogen species, erythropoiesis, and the histaminergic system. ...Of concern should be findings of hepatic enlargement and inc …
L-histidine (HIS) is an essential amino acid with unique roles in proton buffering, metal ion chelation, scavenging of reactiv …
Metabolic Pathways Fueling the Endothelial Cell Drive.
Li X, Kumar A, Carmeliet P. Li X, et al. Annu Rev Physiol. 2019 Feb 10;81:483-503. doi: 10.1146/annurev-physiol-020518-114731. Annu Rev Physiol. 2019. PMID: 30742787 Review.
Endothelial cell (EC) metabolism is important for health and disease. Metabolic pathways, such as glycolysis, fatty acid oxidation, and amino acid metabolism, determine vasculature formation. ...Emerging evidence demonstrates that …
Endothelial cell (EC) metabolism is important for health and disease. Metabolic pathways, such as glycolysis, fatty …
18,905 results
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