Skip to main page content
U.S. flag

An official website of the United States government

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

1989
2025

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 1
1992 2
1996 1
1998 1
2001 2
2002 1
2004 1
2007 1
2009 1
2010 1
2011 1
2012 2
2013 1
2014 1
2016 1
2017 1
2023 1
2024 1
2025 0

Publication date

Text availability

Article attribute

Article type

Additional filters

Search Results

20 results

Results by year

Filters applied: . Clear all
Page 1
Beta-thalassemia.
Galanello R, Origa R. Galanello R, et al. Orphanet J Rare Dis. 2010 May 21;5:11. doi: 10.1186/1750-1172-5-11. Orphanet J Rare Dis. 2010. PMID: 20492708 Free PMC article. Review.
Transmission is autosomal recessive; however, dominant mutations have also been reported. Diagnosis of thalassemia is based on hematologic and molecular genetic testing. ...Prognosis for individuals with beta-thalassemia has improved substantially in t …
Transmission is autosomal recessive; however, dominant mutations have also been reported. Diagnosis of thalassemia is based on …
The molecular basis of beta-thalassemia.
Thein SL. Thein SL. Cold Spring Harb Perspect Med. 2013 May 1;3(5):a011700. doi: 10.1101/cshperspect.a011700. Cold Spring Harb Perspect Med. 2013. PMID: 23637309 Free PMC article. Review.
Most beta-thalassemias are inherited in a Mendelian recessive fashion but there is a subgroup of beta-thalassemia alleles that behave as dominant negatives. Unraveling the molecular basis of beta-thalassemia has provided a paradigm for un …
Most beta-thalassemias are inherited in a Mendelian recessive fashion but there is a subgroup of beta-thalassemia allel …
Diverse hematological phenotypes of beta-thalassemia carriers.
Luo HY, Chui DH. Luo HY, et al. Ann N Y Acad Sci. 2016 Mar;1368(1):49-55. doi: 10.1111/nyas.13056. Epub 2016 Apr 28. Ann N Y Acad Sci. 2016. PMID: 27123947 Review.
Most beta-thalassemia carriers have mild anemia, low mean corpuscular volume and mean corpuscular hemoglobin, and elevated hemoglobin alpha2 (HbA2 ). However, there is considerable variability resulting from coinheritance with alpha- and/or delta-globin gene mutatio …
Most beta-thalassemia carriers have mild anemia, low mean corpuscular volume and mean corpuscular hemoglobin, and elevated hem …
Clonal hematopoiesis and acquired genetic abnormalities of the red cell: An historical review.
Lichtman MA. Lichtman MA. Blood Cells Mol Dis. 2024 Jan;104:102801. doi: 10.1016/j.bcmd.2023.102801. Epub 2023 Nov 5. Blood Cells Mol Dis. 2024. PMID: 37951089 Review.
The syndromes include disorders of globin chain synthesis (alpha- and beta-thalassemia), heme synthesis (erythropoietic porphyria and erythropoietic uroporphyria), red cell membrane structure (elliptocytosis and spherocytosis), red cell enzyme activity (pyruvate kin …
The syndromes include disorders of globin chain synthesis (alpha- and beta-thalassemia), heme synthesis (erythropoietic porphy …
Uncommon Causes of Cerebral Microbleeds.
Noorbakhsh-Sabet N, Pulakanti VC, Zand R. Noorbakhsh-Sabet N, et al. J Stroke Cerebrovasc Dis. 2017 Oct;26(10):2043-2049. doi: 10.1016/j.jstrokecerebrovasdis.2017.07.012. Epub 2017 Aug 18. J Stroke Cerebrovasc Dis. 2017. PMID: 28826581 Review.
RESULTS: CMBs have several uncommon etiologies including posterior reversible encephalopathy syndrome, infective endocarditis, brain radiation therapy, cocaine abuse, thrombotic thrombocytopenic purpura, traumatic brain injury, intravascular lymphomatosis or proliferating angio-e …
RESULTS: CMBs have several uncommon etiologies including posterior reversible encephalopathy syndrome, infective endocarditis, brain radiati …
Development of gene therapy for thalassemia.
Nienhuis AW, Persons DA. Nienhuis AW, et al. Cold Spring Harb Perspect Med. 2012 Nov 1;2(11):a011833. doi: 10.1101/cshperspect.a011833. Cold Spring Harb Perspect Med. 2012. PMID: 23125203 Free PMC article. Review.
Retroviral vector-mediated gene transfer into hematopoietic stem cells provides a potentially curative therapy for severe beta-thalassemia. Lentiviral vectors based on human immunodeficiency virus have been developed for this purpose and have been shown to be effect …
Retroviral vector-mediated gene transfer into hematopoietic stem cells provides a potentially curative therapy for severe beta-tha
Current advances in retroviral gene therapy.
Yi Y, Noh MJ, Lee KH. Yi Y, et al. Curr Gene Ther. 2011 Jun;11(3):218-28. doi: 10.2174/156652311795684740. Curr Gene Ther. 2011. PMID: 21453283 Free PMC article. Review.
Due to the risk of oncogenesis caused by retroviral insertional activation of host genes, most of the efforts focused on the lentiviral therapies. However, a relative clonal dominance was detected in a patient with beta-thalassemia Major, two years after the …
Due to the risk of oncogenesis caused by retroviral insertional activation of host genes, most of the efforts focused on the lentiviral ther …
Advances in stem cell transplantation and gene therapy in the beta-hemoglobinopathies.
Payen E, Leboulch P. Payen E, et al. Hematology Am Soc Hematol Educ Program. 2012;2012:276-83. doi: 10.1182/asheducation-2012.1.276. Hematology Am Soc Hematol Educ Program. 2012. PMID: 23233592 Review.
High-level production of beta-globin, gamma-globin, or therapeutic mutant globins in the RBC lineage by hematopoietic stem cell gene therapy ameliorates or cures the hemoglobinopathies sickle cell disease and beta thalassemia, which are major causes of morbid …
High-level production of beta-globin, gamma-globin, or therapeutic mutant globins in the RBC lineage by hematopoietic stem cell gene …
The beta-globin dominant control region.
Greaves DR, Antoniou M, van Assendelft GB, Collis P, Dillon N, Hanscombe O, Hurst J, Lindenbaum M, Talbot D, Grosveld F. Greaves DR, et al. Prog Clin Biol Res. 1989;316A:37-46. Prog Clin Biol Res. 1989. PMID: 2687892 Review. No abstract available.
Heart disease in thalassemia intermedia: a review of the underlying pathophysiology.
Aessopos A, Kati M, Farmakis D. Aessopos A, et al. Haematologica. 2007 May;92(5):658-65. doi: 10.3324/haematol.10915. Haematologica. 2007. PMID: 17488690 Free article. Review.
Heart disease is the leading cause of mortality and one of the main causes of morbidity in beta-thalassemia. The clinical spectrum of the thalassemia syndrome ranges from the severe, transfusion--dependent thalassemia major and the asymptomatic carrier …
Heart disease is the leading cause of mortality and one of the main causes of morbidity in beta-thalassemia. The clinical spec …
20 results