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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1976 1
1980 1
1983 1
1984 2
1985 1
1986 1
1987 3
1988 6
1989 3
1990 1
1991 7
1992 6
1993 8
1994 7
1995 8
1996 10
1997 7
1998 6
1999 7
2000 5
2001 6
2002 5
2003 8
2004 6
2005 8
2006 8
2007 10
2008 10
2009 6
2010 15
2011 12
2012 19
2013 15
2014 14
2015 11
2016 14
2017 9
2018 7
2019 13
2020 15
2021 16
2022 10
2023 15
2024 4

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316 results

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Page 1
MELAS syndrome: Clinical manifestations, pathogenesis, and treatment options.
El-Hattab AW, Adesina AM, Jones J, Scaglia F. El-Hattab AW, et al. Mol Genet Metab. 2015 Sep-Oct;116(1-2):4-12. doi: 10.1016/j.ymgme.2015.06.004. Epub 2015 Jun 15. Mol Genet Metab. 2015. PMID: 26095523 Review.
Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome is one of the most frequent maternally inherited mitochondrial disorders. ...Unblinded studies showed that l-arginine therapy improves stroke-like episode symptoms and …
Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome is one of the most frequent matern …
Diabetic ketoacidosis in pregnancy.
Sibai BM, Viteri OA. Sibai BM, et al. Obstet Gynecol. 2014 Jan;123(1):167-178. doi: 10.1097/AOG.0000000000000060. Obstet Gynecol. 2014. PMID: 24463678 Review.
Management principles include aggressive volume replacement, initiation of intravenous insulin therapy, correction of acidosis, correction of electrolyte abnormalities and management of precipitating factors, as well as monitoring of maternal-fetal response to treatment. . …
Management principles include aggressive volume replacement, initiation of intravenous insulin therapy, correction of acidosis, corre …
MELAS: Phenotype Classification into Classic-versus-Atypical Presentations.
Alves CAPF, Zandifar A, Peterson JT, Tara SZ, Ganetzky R, Viaene AN, Andronikou S, Falk MJ, Vossough A, Goldstein AC. Alves CAPF, et al. AJNR Am J Neuroradiol. 2023 May;44(5):602-610. doi: 10.3174/ajnr.A7837. Epub 2023 Apr 6. AJNR Am J Neuroradiol. 2023. PMID: 37024306 Review.
BACKGROUND AND PURPOSE: An increased number of pathogenic variants have been described in mitochondrial encephalomyopathy lactic acidosis and strokelike episodes (MELAS). Different imaging presentations have emerged in parallel with a growing recognition of clinical …
BACKGROUND AND PURPOSE: An increased number of pathogenic variants have been described in mitochondrial encephalomyopathy lactic acidosis …
Mitochondrial medicine therapies: rationale, evidence, and dosing guidelines.
Barcelos I, Shadiack E, Ganetzky RD, Falk MJ. Barcelos I, et al. Curr Opin Pediatr. 2020 Dec;32(6):707-718. doi: 10.1097/MOP.0000000000000954. Curr Opin Pediatr. 2020. PMID: 33105273 Free PMC article. Review.
Long-term follow up on L-arginine use as prophylaxis against or acute treatment for metabolic strokes has provided more data supporting its clinical use in individuals with mitochondrial encephalopathy with lactic acidosis and stroke-like episodes (MELAS) syn …
Long-term follow up on L-arginine use as prophylaxis against or acute treatment for metabolic strokes has provided more data supporti …
Subcutaneous rapid-acting insulin analogues for diabetic ketoacidosis.
Andrade-Castellanos CA, Colunga-Lozano LE, Delgado-Figueroa N, Gonzalez-Padilla DA. Andrade-Castellanos CA, et al. Cochrane Database Syst Rev. 2016 Jan 21;2016(1):CD011281. doi: 10.1002/14651858.CD011281.pub2. Cochrane Database Syst Rev. 2016. PMID: 26798030 Free PMC article. Review.
There was low-quality evidence to evaluate the effects of subcutaneous rapid-acting insulin analogues versus intravenous regular insulin on hypoglycaemic episodes: 6 of 80 insulin lispro-treated participants compared with 9 of 76 regular insulin-treated participants report …
There was low-quality evidence to evaluate the effects of subcutaneous rapid-acting insulin analogues versus intravenous regular insulin on …
Clinical features, pathogenesis, and management of stroke-like episodes due to MELAS.
Tetsuka S, Ogawa T, Hashimoto R, Kato H. Tetsuka S, et al. Metab Brain Dis. 2021 Dec;36(8):2181-2193. doi: 10.1007/s11011-021-00772-x. Epub 2021 Jun 12. Metab Brain Dis. 2021. PMID: 34118021 Review.
Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) is a disease that should be considered as a differential diagnosis to acute ischemic stroke taking into account its onset pattern and neurological symptoms, which are similar to th …
Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) is a disease that should be considered a …
When should MELAS (Mitochondrial myopathy, Encephalopathy, Lactic Acidosis, and Stroke-like episodes) be the diagnosis?
Lorenzoni PJ, Werneck LC, Kay CS, Silvado CE, Scola RH. Lorenzoni PJ, et al. Arq Neuropsiquiatr. 2015 Nov;73(11):959-67. doi: 10.1590/0004-282X20150154. Arq Neuropsiquiatr. 2015. PMID: 26517220 Free article. Review.
Mitochondrial myopathy, Encephalopathy, Lactic Acidosis, and Stroke-like episodes (MELAS) is a rare mitochondrial disorder. Diagnostic criteria for MELAS include typical manifestations of the disease: stroke-like episodes, encephalopathy, evidence of mitochon …
Mitochondrial myopathy, Encephalopathy, Lactic Acidosis, and Stroke-like episodes (MELAS) is a rare mitochondrial disorder. Di …
Diabetic ketoacidosis in pregnancy - Case series, pathophysiology, and review of the literature.
Eshkoli T, Barski L, Faingelernt Y, Jotkowitz A, Finkel-Oron A, Schwarzfuchs D. Eshkoli T, et al. Eur J Obstet Gynecol Reprod Biol. 2022 Feb;269:41-46. doi: 10.1016/j.ejogrb.2021.12.011. Epub 2021 Dec 21. Eur J Obstet Gynecol Reprod Biol. 2022. PMID: 34968873 Review.
The pathophysiology of DKA in pregnancy has its own characteristics due to multiple factors, such as insulin resistance, accelerated starvation and respiratory alkalosis, thus creating ketosis-prone state, with DKA occurring at milder degrees of hyperglycemia, even in normoglycem …
The pathophysiology of DKA in pregnancy has its own characteristics due to multiple factors, such as insulin resistance, accelerated starvat …
SGLT2 Inhibitors: A Systematic Review of Diabetic Ketoacidosis and Related Risk Factors in the Primary Literature.
Burke KR, Schumacher CA, Harpe SE. Burke KR, et al. Pharmacotherapy. 2017 Feb;37(2):187-194. doi: 10.1002/phar.1881. Epub 2017 Jan 16. Pharmacotherapy. 2017. PMID: 27931088 Review.
Search terms included canagliflozin, dapagliflozin, empagliflozin, SGLT2, sodium glucose cotransporter-2 inhibitor, diabetic ketoacidosis, ketoacidosis, metabolic acidosis, and acidosis. Primary literature was analyzed via descriptive statistics. ...Common pr …
Search terms included canagliflozin, dapagliflozin, empagliflozin, SGLT2, sodium glucose cotransporter-2 inhibitor, diabetic ketoacidosis, k …
The Heart in Diabetic Ketoacidosis: A Narrative Review Focusing on the Acute Cardiac Effects and Electrocardiographic Abnormalities.
Carrizales-Sepúlveda EF, Vera-Pineda R, Jiménez-Castillo RA, Violante-Cumpa JR, Flores-Ramírez R, Ordaz-Farías A. Carrizales-Sepúlveda EF, et al. Am J Med Sci. 2021 Jun;361(6):690-701. doi: 10.1016/j.amjms.2020.11.030. Epub 2020 Nov 26. Am J Med Sci. 2021. PMID: 33941367 Review.
Diabetic ketoacidosis (DKA) is a serious complication of diabetes mellitus. Hyperglycemia, acidosis, and electrolyte imbalances can directly affect the heart by inducing toxicity, impairing myocardial blood flow, autonomic dysfunction, and altering activation and conductio …
Diabetic ketoacidosis (DKA) is a serious complication of diabetes mellitus. Hyperglycemia, acidosis, and electrolyte imbalances can d …
316 results