Gene of the month: BAP1.
Wang A, Papneja A, Hyrcza M, Al-Habeeb A, Ghazarian D.
Wang A, et al.
J Clin Pathol. 2016 Sep;69(9):750-3. doi: 10.1136/jclinpath-2016-203866. Epub 2016 May 27.
J Clin Pathol. 2016.
PMID: 27235536
Review.
The BAP1 gene (BRCA1-associated protein 1) is a tumour suppressor gene that encodes a deubiquitinating enzyme (DUB), regulating key cellular pathways, including cell cycle, cellular differentiation, transcription and DNA damage response. Germline BAP1 mutations cause a nov …
The BAP1 gene (BRCA1-associated protein 1) is a tumour suppressor gene that encodes a deubiquitinating enzyme (DUB), regulating key cellular …