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Page 1
Molecular basis of intrahepatic cholestasis.
Carlton VE, Pawlikowska L, Bull LN. Carlton VE, et al. Ann Med. 2004;36(8):606-17. doi: 10.1080/07853890410018916. Ann Med. 2004. PMID: 15768832 Free article. Review.
ATP8B1 (FIC1), ABCB11 (BSEP), and ABCB4 (MDR3) are disrupted in forms of progressive familial intrahepatic cholestasis (PFIC) and related disorders. Mutations in BAAT, TJP2 (ZO-2), and EPHX1 have been identified in patients with hypercholanemia. ...
ATP8B1 (FIC1), ABCB11 (BSEP), and ABCB4 (MDR3) are disrupted in forms of progressive familial intrahepatic cholestasis (PFIC) and rel …
The emerging role of acyl-CoA thioesterases and acyltransferases in regulating peroxisomal lipid metabolism.
Hunt MC, Siponen MI, Alexson SE. Hunt MC, et al. Biochim Biophys Acta. 2012 Sep;1822(9):1397-410. doi: 10.1016/j.bbadis.2012.03.009. Epub 2012 Mar 23. Biochim Biophys Acta. 2012. PMID: 22465940 Free article. Review.
Similarly, human peroxisomes contain one bile acid-CoA:amino acid N-acyltransferase (BAAT), whereas mouse peroxisomes contain three acyltransferases (BAAT and acyl-CoA:amino acid N-acyltransferases 1 and 2: ACNAT1 and ACNAT2). This review will focus on the human and mouse …
Similarly, human peroxisomes contain one bile acid-CoA:amino acid N-acyltransferase (BAAT), whereas mouse peroxisomes contain three acyltran …