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Current understanding of iron homeostasis.
Anderson GJ, Frazer DM. Anderson GJ, et al. Am J Clin Nutr. 2017 Dec;106(Suppl 6):1559S-1566S. doi: 10.3945/ajcn.117.155804. Epub 2017 Oct 25. Am J Clin Nutr. 2017. PMID: 29070551 Free PMC article. Review.
This iron can be used for metabolic functions, stored within cytosolic ferritin, or exported from the cell via FPN1. Cellular iron concentrations are modulated by the iron regulatory proteins (IRPs) IRP1 and IRP2. ...These disorders include various forms of hemochro …
This iron can be used for metabolic functions, stored within cytosolic ferritin, or exported from the cell via FPN1. Cellular iron …
Ferric carboxymaltose: a review of its use in iron-deficiency anaemia.
Lyseng-Williamson KA, Keating GM. Lyseng-Williamson KA, et al. Drugs. 2009;69(6):739-56. doi: 10.2165/00003495-200969060-00007. Drugs. 2009. PMID: 19405553 Review.
The total iron concentration in the serum increased rapidly in a dose-dependent manner after intravenous administration of ferric carboxymaltose. Ferric carboxymaltose is rapidly cleared from the circulation and is distributed primarily to the bone marrow ( a …
The total iron concentration in the serum increased rapidly in a dose-dependent manner after intravenous administration of fer …
New Perspectives on Circulating Ferritin: Its Role in Health and Disease.
Fonseca Ó, Ramos AS, Gomes LTS, Gomes MS, Moreira AC. Fonseca Ó, et al. Molecules. 2023 Nov 22;28(23):7707. doi: 10.3390/molecules28237707. Molecules. 2023. PMID: 38067440 Free PMC article. Review.
This presents a particularly puzzling challenge for the clinician evaluating the overall iron status of the patient in the presence of an inflammatory condition. The increase in serum ferritin during inflammation is one of the enigmas regarding iron metabolism. ...T …
This presents a particularly puzzling challenge for the clinician evaluating the overall iron status of the patient in the presence of an in …
Iron Status and Gestational Diabetes-A Meta-Analysis.
Kataria Y, Wu Y, Horskjær PH, Mandrup-Poulsen T, Ellervik C. Kataria Y, et al. Nutrients. 2018 May 15;10(5):621. doi: 10.3390/nu10050621. Nutrients. 2018. PMID: 29762515 Free PMC article. Review.
Adjusted odds ratio for GDM were 1.58 (95% CI: 1.20-2.08) for ferritin, 1.30 (1.01-1.67) for hemoglobin, and 1.48 (1.29-1.69) for dietary heme intake. We did not find any differences in TIBC or transferrin concentration in women with and without GDM. We also did not …
Adjusted odds ratio for GDM were 1.58 (95% CI: 1.20-2.08) for ferritin, 1.30 (1.01-1.67) for hemoglobin, and 1.48 (1.29-1.69) for die …
Iron status in the elderly.
Fairweather-Tait SJ, Wawer AA, Gillings R, Jennings A, Myint PK. Fairweather-Tait SJ, et al. Mech Ageing Dev. 2014 Mar-Apr;136-137:22-8. doi: 10.1016/j.mad.2013.11.005. Epub 2013 Nov 22. Mech Ageing Dev. 2014. PMID: 24275120 Free PMC article. Review.
Iron deficiency anaemia is prevalent in older age, particularly after the age of 80. Serum ferritin concentrations also decline, although there is no evidence to suggest that changes in iron stores are an inevitable consequence of ageing. ...Brain iron levels are …
Iron deficiency anaemia is prevalent in older age, particularly after the age of 80. Serum ferritin concentrations also declin …
Iron and the risk of infection.
Pieracci FM, Barie PS. Pieracci FM, et al. Surg Infect (Larchmt). 2005;6 Suppl 1:S41-6. doi: 10.1089/sur.2005.6.s1-41. Surg Infect (Larchmt). 2005. PMID: 19284357 Review.
Humans utilize the iron-binding proteins lactoferrin, transferrin, and ferritin to move Fe away from sites of infection and into storage. ...RESULTS: Iron overload leads to inhibition of IFN-gamma, TNF-alpha, IL-12, and nitric oxide formation as well as impairment of macro …
Humans utilize the iron-binding proteins lactoferrin, transferrin, and ferritin to move Fe away from sites of infection and into stor …
Brain iron homeostasis.
Moos T. Moos T. Dan Med Bull. 2002 Nov;49(4):279-301. Dan Med Bull. 2002. PMID: 12553165 Review.
This thesis deals with the topic "brain iron homeostasis" defined as the attempts to maintain constant concentrations of iron in the brain internal environment via regulation of iron transport through brain barriers, cellular iron uptake by neurons and glia, and export of …
This thesis deals with the topic "brain iron homeostasis" defined as the attempts to maintain constant concentrations of iron in the …
Timing of umbilical cord clamping after birth for optimizing placental transfusion.
Raju TN. Raju TN. Curr Opin Pediatr. 2013 Apr;25(2):180-7. doi: 10.1097/MOP.0b013e32835d2a9e. Curr Opin Pediatr. 2013. PMID: 23407180 Review.
RECENT FINDINGS: In term infants, umbilical cord clamping between 30 and 180 s after birth results in higher concentrations of hemoglobin and hematocrit during the neonatal period, and increased serum ferritin levels and a lower incidence of iron-deficiency a …
RECENT FINDINGS: In term infants, umbilical cord clamping between 30 and 180 s after birth results in higher concentrations of hemogl …
[Biochemical markers of iron status].
Aimone-Gastin I. Aimone-Gastin I. Nephrol Ther. 2006 Nov;2 Suppl 5:S321-6. Nephrol Ther. 2006. PMID: 17373277 Review. French.
Traditionally, the standard biochemical markers of iron status are serum iron, transferrin, transferrin saturation, ferritin and, more recently, soluble transferrin receptor. Diagnosis of iron deficiency is usually associated with a low serum ferritin concentrati …
Traditionally, the standard biochemical markers of iron status are serum iron, transferrin, transferrin saturation, ferritin and, mor …
Predicting the hematopoietic response to recombinant human erythropoietin (Epoetin alfa) in the treatment of the anemia of cancer.
Adamson JW, Ludwig H. Adamson JW, et al. Oncology. 1999;56(1):46-53. doi: 10.1159/000011929. Oncology. 1999. PMID: 9885377 Review.
Recombinant human erythropoietin (Epoetin alfa) is effective in increasing hemoglobin concentration and hematocrit, and in significantly reducing transfusion requirements in the majority of patients with either the anemia of chronic renal failure or chemotherapy-ind …
Recombinant human erythropoietin (Epoetin alfa) is effective in increasing hemoglobin concentration and hematocrit, and in sig …
12 results