The Coxib case: Are EP receptors really guilty?
Santilli F, Boccatonda A, Davì G, Cipollone F.
Santilli F, et al.
Atherosclerosis. 2016 Jun;249:164-73. doi: 10.1016/j.atherosclerosis.2016.04.004. Epub 2016 Apr 6.
Atherosclerosis. 2016.
PMID: 27105159
Review.
COX consists of two isoforms, called COX-1 and COX-2. Increasing drug selectivity for COX-2 is associated with higher CV risk. Indeed, Coxibs are shown to favour a prothrombotic state, predisposing patients to myocardial infarction (MI) or thrombotic stroke, and to counter …
COX consists of two isoforms, called COX-1 and COX-2. Increasing drug selectivity for COX-2 is associated with higher CV risk. Indeed …