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1975
2025

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 2
1978 1
1981 2
1983 2
1985 2
1986 3
1988 1
1989 2
1991 3
1992 3
1993 1
1994 1
1996 6
1997 1
1998 3
2000 2
2001 1
2004 3
2005 1
2006 4
2007 4
2008 3
2009 2
2010 3
2011 2
2012 2
2013 1
2014 3
2015 3
2016 1
2017 1
2018 3
2019 1
2020 1
2022 1
2025 0

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72 results

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Page 1
Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects.
Nehlig A, Daval JL, Debry G. Nehlig A, et al. Brain Res Brain Res Rev. 1992 May-Aug;17(2):139-70. doi: 10.1016/0165-0173(92)90012-b. Brain Res Brain Res Rev. 1992. PMID: 1356551 Review.
Caffeine increases energy metabolism throughout the brain but decreases at the same time cerebral blood flow, inducing a relative brain hypoperfusion. ...The methylxanthine induces dose-response increases in locomotor activity in animals. Its psychostimulant …
Caffeine increases energy metabolism throughout the brain but decreases at the same time cerebral blood flow, inducing a relat …
Cellular adaptation to hypoxia through hypoxia inducible factors and beyond.
Lee P, Chandel NS, Simon MC. Lee P, et al. Nat Rev Mol Cell Biol. 2020 May;21(5):268-283. doi: 10.1038/s41580-020-0227-y. Epub 2020 Mar 6. Nat Rev Mol Cell Biol. 2020. PMID: 32144406 Free PMC article. Review.
Molecular oxygen (O(2)) sustains intracellular bioenergetics and is consumed by numerous biochemical reactions, making it essential for most species on Earth. Accordingly, decreased oxygen concentration (hypoxia) is a major stressor that generally subverts life of aerobic …
Molecular oxygen (O(2)) sustains intracellular bioenergetics and is consumed by numerous biochemical reactions, making it essential for most …
Adenosine and preeclampsia.
Salsoso R, Farías M, Gutiérrez J, Pardo F, Chiarello DI, Toledo F, Leiva A, Mate A, Vázquez CM, Sobrevia L. Salsoso R, et al. Mol Aspects Med. 2017 Jun;55:126-139. doi: 10.1016/j.mam.2016.12.003. Epub 2017 Jan 12. Mol Aspects Med. 2017. PMID: 28089907 Free article. Review.
Since the proposed mechanisms of preeclampsia development include adenosine-dependent biological effects, adenosine membrane transporters and receptors, and the associated signalling mechanisms might play a role in the pathophysiology of preeclampsia. Preeclampsia associates with …
Since the proposed mechanisms of preeclampsia development include adenosine-dependent biological effects, adenosine membrane transporters an …
Acute rhabdomyolysis and inflammation.
Hamel Y, Mamoune A, Mauvais FX, Habarou F, Lallement L, Romero NB, Ottolenghi C, de Lonlay P. Hamel Y, et al. J Inherit Metab Dis. 2015 Jul;38(4):621-8. doi: 10.1007/s10545-015-9827-7. Epub 2015 Mar 17. J Inherit Metab Dis. 2015. PMID: 25778939 Review.
Rhabdomyolysis results from the rapid breakdown of skeletal muscle fibers, which leads to leakage of potentially toxic cellular content into the systemic circulation. Acquired causes by direct injury to the sarcolemma are most frequent. The inherited causes are: i) metabol …
Rhabdomyolysis results from the rapid breakdown of skeletal muscle fibers, which leads to leakage of potentially toxic cellular content into …
Coronary physiology.
Feigl EO. Feigl EO. Physiol Rev. 1983 Jan;63(1):1-205. doi: 10.1152/physrev.1983.63.1.1. Physiol Rev. 1983. PMID: 6296890 Review.
The major areas of normal coronary physiological research since Berne's 1964 review have been the measurement of ventricular transmural blood flow distribution with microspheres, the adenosine hypothesis of local metabolic control of coronary blood flow, and the aut …
The major areas of normal coronary physiological research since Berne's 1964 review have been the measurement of ventricular transmural b
Metabolic effects of alcohol.
Mezey E. Mezey E. Fed Proc. 1985 Jan;44(1 Pt 1):134-8. Fed Proc. 1985. PMID: 3881285 Review.
Increases in serum lactate, resulting from the increased NADH/NAD+ ratio, and hyperuricemia, most likely the result of increased turnover of adenine nucleotides, are common transient effects of ethanol ingestion. ...Ethanol decreases thiamine absorption and d
Increases in serum lactate, resulting from the increased NADH/NAD+ ratio, and hyperuricemia, most likely the result of incr
Uric acid and the cardio-renal effects of SGLT2 inhibitors.
Bailey CJ. Bailey CJ. Diabetes Obes Metab. 2019 Jun;21(6):1291-1298. doi: 10.1111/dom.13670. Epub 2019 Mar 15. Diabetes Obes Metab. 2019. PMID: 30762288 Review.
This review evaluates evidence that an effect of SGLT2 inhibitors to lower uric acid may also contribute to reduced cardio-renal risk. Chronically elevated circulating uric acid concentrations are associated with increased risk of hypertension, CV disease and …
This review evaluates evidence that an effect of SGLT2 inhibitors to lower uric acid may also contribute to reduced cardio-renal risk. Chron …
Dynamic heterogeneity of exercising muscle blood flow and O2 utilization.
Koga S, Rossiter HB, Heinonen I, Musch TI, Poole DC. Koga S, et al. Med Sci Sports Exerc. 2014;46(5):860-76. doi: 10.1249/MSS.0000000000000178. Med Sci Sports Exerc. 2014. PMID: 24091989 Review.
For this to occur, muscle O2 delivery (i.e., blood flow arterial O2 concentration) must be coordinated superbly with muscle O2 requirements (VO2), the efficacy of which may differ among muscles and distinct fiber types. ...This forces greater influence of the upstre …
For this to occur, muscle O2 delivery (i.e., blood flow arterial O2 concentration) must be coordinated superbly with muscle O2 …
Effects of glycine on metabolic syndrome components: a review.
Imenshahidi M, Hossenzadeh H. Imenshahidi M, et al. J Endocrinol Invest. 2022 May;45(5):927-939. doi: 10.1007/s40618-021-01720-3. Epub 2022 Jan 11. J Endocrinol Invest. 2022. PMID: 35013990 Review.
It is mainly generated in the liver and kidney and is used to produce collagen, creatine, glucose and purine. It is also involved in immune function, anti-inflammatory processes and anti-oxidation reactions. ...Interventions such as lifestyle modification, exercise, weight …
It is mainly generated in the liver and kidney and is used to produce collagen, creatine, glucose and purine. It is also involved in …
Ammonia metabolism.
Tannen RL. Tannen RL. Am J Physiol. 1978 Oct;235(4):F265-77. doi: 10.1152/ajprenal.1978.235.4.F265. Am J Physiol. 1978. PMID: 29492 Review.
The pathways responsible for an the mechanisms underlying the adaptive increase in ammonia production in response to acidosis are considered. It seems unlikely that the cytosolic pathways (glutamine synthetase, glutaminase II, phosphate-independent glutaminase, and gamma-g …
The pathways responsible for an the mechanisms underlying the adaptive increase in ammonia production in response to acidosis are con …
72 results