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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 1
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1979 3
1984 1
1987 2
1990 1
1991 3
1993 3
1994 3
1995 4
1997 2
1998 3
1999 1
2000 1
2001 3
2003 1
2004 1
2005 3
2006 2
2007 2
2008 4
2010 1
2012 1
2013 5
2014 4
2015 3
2016 1
2017 1
2018 1
2019 4
2020 4
2021 2
2023 4
2024 0

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72 results

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Page 1
Gene Therapy of Sphingolipid Metabolic Disorders.
Shaimardanova AA, Solovyeva VV, Issa SS, Rizvanov AA. Shaimardanova AA, et al. Int J Mol Sci. 2023 Feb 11;24(4):3627. doi: 10.3390/ijms24043627. Int J Mol Sci. 2023. PMID: 36835039 Free PMC article. Review.
This group of lysosomal storage diseases includes more than 10 genetic disorders, including GM1-gangliosidosis, Tay-Sachs disease, Sandhoff disease, the AB variant of GM2-gangliosidosis, Fabry disease, Gaucher disease, metachromatic leukodystrophy, Krabbe dis …
This group of lysosomal storage diseases includes more than 10 genetic disorders, including GM1-gangliosidosis, Tay-Sachs dise …
Mitochondria-associated membranes in aging and senescence: structure, function, and dynamics.
Janikiewicz J, Szymański J, Malinska D, Patalas-Krawczyk P, Michalska B, Duszyński J, Giorgi C, Bonora M, Dobrzyn A, Wieckowski MR. Janikiewicz J, et al. Cell Death Dis. 2018 Feb 28;9(3):332. doi: 10.1038/s41419-017-0105-5. Cell Death Dis. 2018. PMID: 29491385 Free PMC article. Review.
Recently, MAM have also been studied in the context of different pathologies, including Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, type 2 diabetes mellitus and GM1-gangliosidosis. An underappreciated amount of data links MAM with aging …
Recently, MAM have also been studied in the context of different pathologies, including Alzheimer's disease, Parkinson's disease, amyotrophi …
Gangliosidoses.
Patterson MC. Patterson MC. Handb Clin Neurol. 2013;113:1707-8. doi: 10.1016/B978-0-444-59565-2.00039-3. Handb Clin Neurol. 2013. PMID: 23622392 Review.
The gangliosidoses comprise a family of lysosomal storage diseases characterized by the accumulation of complex glycosphingolipids in the nervous system and other tissues, secondary to the deficient activity of lysosomal hydrolases or their associated activator proteins. GM1 …
The gangliosidoses comprise a family of lysosomal storage diseases characterized by the accumulation of complex glycosphingolipids in the ne …
The natural history of Type 1 infantile GM1 gangliosidosis: A literature-based meta-analysis.
Lang FM, Korner P, Harnett M, Karunakara A, Tifft CJ. Lang FM, et al. Mol Genet Metab. 2020 Mar;129(3):228-235. doi: 10.1016/j.ymgme.2019.12.012. Epub 2019 Dec 30. Mol Genet Metab. 2020. PMID: 31937438 Free PMC article. Review.
INTRODUCTION: Type 1 GM1 gangliosidosis is an ultra-rare, rapidly fatal lysosomal storage disorder, with life expectancy of <3 years of age. ...METHODS: PubMed was searched with the keyword "GM1 Gangliosidosis" and for articles from the year 2000 on …
INTRODUCTION: Type 1 GM1 gangliosidosis is an ultra-rare, rapidly fatal lysosomal storage disorder, with life expectancy of &l …
Metabolic cardiomyopathies.
Guertl B, Noehammer C, Hoefler G. Guertl B, et al. Int J Exp Pathol. 2000 Dec;81(6):349-72. doi: 10.1046/j.1365-2613.2000.00186.x. Int J Exp Pathol. 2000. PMID: 11298185 Free PMC article. Review.
Niemann-Pick disease, Gaucher disease, I-cell disease, various types of mucopolysaccharidoses, GM1 gangliosidosis, galactosialidosis, carbohydrate-deficient glycoprotein syndromes and Sandhoff's disease). ...
Niemann-Pick disease, Gaucher disease, I-cell disease, various types of mucopolysaccharidoses, GM1 gangliosidosis, galactosial …
Ganglioside GM1 and the Central Nervous System.
Guo Z. Guo Z. Int J Mol Sci. 2023 May 31;24(11):9558. doi: 10.3390/ijms24119558. Int J Mol Sci. 2023. PMID: 37298512 Free PMC article. Review.
GM1 is one of the major glycosphingolipids (GSLs) on the cell surface in the central nervous system (CNS). ...Overall, GM1 is protective for the CNS. Additionally, this review has also examined the relationships between GM1 and neurological disorders, such as …
GM1 is one of the major glycosphingolipids (GSLs) on the cell surface in the central nervous system (CNS). ...Overall, GM1 is …
Lyso-glycosphingolipids: presence and consequences.
van Eijk M, Ferraz MJ, Boot RG, Aerts JMFG. van Eijk M, et al. Essays Biochem. 2020 Sep 23;64(3):565-578. doi: 10.1042/EBC20190090. Essays Biochem. 2020. PMID: 32808655 Free PMC article. Review.
In lysosomal storage diseases such as Gaucher Disease, Fabry Disease, Krabbe disease, GM1 -and GM2 gangliosidosis, Niemann Pick type C and Metachromatic leukodystrophy massive intra-lysosomal glycosphingolipid accumulation occurs. ...
In lysosomal storage diseases such as Gaucher Disease, Fabry Disease, Krabbe disease, GM1 -and GM2 gangliosidosis, Niemann Pic …
Lysosomal Glycosphingolipid Storage Diseases.
Breiden B, Sandhoff K. Breiden B, et al. Annu Rev Biochem. 2019 Jun 20;88:461-485. doi: 10.1146/annurev-biochem-013118-111518. Annu Rev Biochem. 2019. PMID: 31220974 Review.
Inherited defects of lysosomal hydrolases or lipid-binding proteins cause the accumulation of undegradable material in lysosomal storage diseases (GM1 and GM2 gangliosidosis; Fabry, Gaucher, and Krabbe diseases; and metachromatic leukodystrophy). ...
Inherited defects of lysosomal hydrolases or lipid-binding proteins cause the accumulation of undegradable material in lysosomal storage dis …
Gene therapy approaches for GM1 gangliosidosis: Focus on animal and cellular studies.
Hosseini K, Fallahi J, Tabei SMB, Razban V. Hosseini K, et al. Cell Biochem Funct. 2023 Dec;41(8):1093-1105. doi: 10.1002/cbf.3887. Epub 2023 Nov 29. Cell Biochem Funct. 2023. PMID: 38018878 Review.
One of the most important inherited metabolic disorders is GM1 gangliosidosis, which is a progressive neurological disorder. ...In this regard, the present article reviews the general features of GM1 gangliosidosis and its mutations, as well as gene th …
One of the most important inherited metabolic disorders is GM1 gangliosidosis, which is a progressive neurological disorder. . …
The GM1 and GM2 Gangliosidoses: Natural History and Progress toward Therapy.
Regier DS, Proia RL, D'Azzo A, Tifft CJ. Regier DS, et al. Pediatr Endocrinol Rev. 2016 Jun;13 Suppl 1(Suppl 1):663-73. Pediatr Endocrinol Rev. 2016. PMID: 27491214 Free PMC article. Review.
The gangliosidoses are lysosomal storage disorders caused by accumulation of GM1 or GM2 gangliosides. GM1 gangliosidosis has both central nervous system and systemic findings; while, GM2 gangliosidosis is restricted primarily to the central nervous sys …
The gangliosidoses are lysosomal storage disorders caused by accumulation of GM1 or GM2 gangliosides. GM1 gangliosidosis …
72 results