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1989
2025

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 1
1990 2
1991 2
1992 10
1993 9
1994 18
1995 13
1996 16
1997 15
1998 5
1999 2
2000 11
2001 14
2002 6
2003 9
2004 3
2005 9
2006 10
2007 14
2008 16
2009 13
2010 10
2011 11
2012 12
2013 11
2014 11
2015 15
2016 14
2017 24
2018 16
2019 21
2020 21
2021 13
2022 19
2023 14
2024 16
2025 0

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390 results

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Page 1
Hematologic malignancies and Li-Fraumeni syndrome.
Swaminathan M, Bannon SA, Routbort M, Naqvi K, Kadia TM, Takahashi K, Alvarado Y, Ravandi-Kashani F, Patel KP, Champlin R, Kantarjian H, Strong L, DiNardo CD. Swaminathan M, et al. Cold Spring Harb Mol Case Stud. 2019 Feb 1;5(1):a003210. doi: 10.1101/mcs.a003210. Print 2019 Feb. Cold Spring Harb Mol Case Stud. 2019. PMID: 30709875 Free PMC article. Review.
Li-Fraumeni syndrome (LFS) is an autosomal dominant condition associated with a high risk of a broad range of childhood- and adult-onset cancers. LFS is related to germline mutations of the tumor-suppressor gene TP53 The most common reported leukemia associat
Li-Fraumeni syndrome (LFS) is an autosomal dominant condition associated with a high risk of a broad range of childhood
Inherited TP53 Mutations and the Li-Fraumeni Syndrome.
Guha T, Malkin D. Guha T, et al. Cold Spring Harb Perspect Med. 2017 Apr 3;7(4):a026187. doi: 10.1101/cshperspect.a026187. Cold Spring Harb Perspect Med. 2017. PMID: 28270529 Free PMC article. Review.
Li-Fraumeni syndrome (LFS) is a complex hereditary cancer predisposition disorder associated with early-onset cancers in diverse tissues of origin. ...
Li-Fraumeni syndrome (LFS) is a complex hereditary cancer predisposition disorder associated with early-onset cancers i
Li-Fraumeni syndrome heterogeneity.
Gargallo P, Yáñez Y, Segura V, Juan A, Torres B, Balaguer J, Oltra S, Castel V, Cañete A. Gargallo P, et al. Clin Transl Oncol. 2020 Jul;22(7):978-988. doi: 10.1007/s12094-019-02236-2. Epub 2019 Nov 5. Clin Transl Oncol. 2020. PMID: 31691207 Review.
Clinical variability is commonly seen in Li-Fraumeni syndrome. Phenotypic heterogeneity is present among different families affected by the same pathogenic variant in TP53 gene and among members of the same family. ...In this review, recent advances in the un …
Clinical variability is commonly seen in Li-Fraumeni syndrome. Phenotypic heterogeneity is present among different fami …
Hereditary Cancer Syndromes: A Comprehensive Review with a Visual Tool.
Garutti M, Foffano L, Mazzeo R, Michelotti A, Da Ros L, Viel A, Miolo G, Zambelli A, Puglisi F. Garutti M, et al. Genes (Basel). 2023 Apr 30;14(5):1025. doi: 10.3390/genes14051025. Genes (Basel). 2023. PMID: 37239385 Free PMC article. Review.
However, diagnosing a hereditary cancer syndrome could be challenging because of a lack of validated testing criteria or because of their suboptimal performance. ...
However, diagnosing a hereditary cancer syndrome could be challenging because of a lack of validated testing criteria or because of t …
Cancer Screening Recommendations for Individuals with Li-Fraumeni Syndrome.
Kratz CP, Achatz MI, Brugières L, Frebourg T, Garber JE, Greer MC, Hansford JR, Janeway KA, Kohlmann WK, McGee R, Mullighan CG, Onel K, Pajtler KW, Pfister SM, Savage SA, Schiffman JD, Schneider KA, Strong LC, Evans DGR, Wasserman JD, Villani A, Malkin D. Kratz CP, et al. Clin Cancer Res. 2017 Jun 1;23(11):e38-e45. doi: 10.1158/1078-0432.CCR-17-0408. Clin Cancer Res. 2017. PMID: 28572266 Review.
Li-Fraumeni syndrome (LFS) is an autosomal dominantly inherited condition caused by germline mutations of the TP53 tumor suppressor gene encoding p53, a transcription factor triggered as a protective cellular mechanism against different stressors. ...Herein,
Li-Fraumeni syndrome (LFS) is an autosomal dominantly inherited condition caused by germline mutations of the TP53 tumo
Pediatric adrenocortical carcinoma.
Ilanchezhian M, Varghese DG, Glod JW, Reilly KM, Widemann BC, Pommier Y, Kaplan RN, Del Rivero J. Ilanchezhian M, et al. Front Endocrinol (Lausanne). 2022 Oct 31;13:961650. doi: 10.3389/fendo.2022.961650. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36387865 Free PMC article. Review.
It is rare in the pediatric population, with an incidence of 0.2-0.3 patients per million in patients under 20 years old. It is primarily associated with Li-Fraumeni and Beckwith-Wiedemann tumor predisposition syndromes in children. The incidence of pediatric ACC is …
It is rare in the pediatric population, with an incidence of 0.2-0.3 patients per million in patients under 20 years old. It is primarily as …
The epidemiology of glioma in adults: a "state of the science" review.
Ostrom QT, Bauchet L, Davis FG, Deltour I, Fisher JL, Langer CE, Pekmezci M, Schwartzbaum JA, Turner MC, Walsh KM, Wrensch MR, Barnholtz-Sloan JS. Ostrom QT, et al. Neuro Oncol. 2014 Jul;16(7):896-913. doi: 10.1093/neuonc/nou087. Neuro Oncol. 2014. PMID: 24842956 Free PMC article. Review.
A small portion of these tumors are caused by Mendelian disorders, including neurofibromatosis, tuberous sclerosis, and Li-Fraumeni syndrome. Genomic analyses of glioma have also produced new evidence about risk and prognosis. ...
A small portion of these tumors are caused by Mendelian disorders, including neurofibromatosis, tuberous sclerosis, and Li-Fraumen
TP53 mutations in human cancers: origins, consequences, and clinical use.
Olivier M, Hollstein M, Hainaut P. Olivier M, et al. Cold Spring Harb Perspect Biol. 2010 Jan;2(1):a001008. doi: 10.1101/cshperspect.a001008. Cold Spring Harb Perspect Biol. 2010. PMID: 20182602 Free PMC article. Review.
Somatic mutations in the TP53 gene are one of the most frequent alterations in human cancers, and germline mutations are the underlying cause of Li-Fraumeni syndrome, which predisposes to a wide spectrum of early-onset cancers. Most mutations are single-base …
Somatic mutations in the TP53 gene are one of the most frequent alterations in human cancers, and germline mutations are the underlying caus …
Cancer genetics and breast cancer.
Huber-Keener KJ. Huber-Keener KJ. Best Pract Res Clin Obstet Gynaecol. 2022 Jun;82:3-11. doi: 10.1016/j.bpobgyn.2022.01.007. Epub 2022 Jan 31. Best Pract Res Clin Obstet Gynaecol. 2022. PMID: 35272929 Review.
Hereditary cancer susceptibility syndromes, including Hereditary Breast and Ovarian Cancer Syndrome (HBOC - BRCA1/2), Cowden Syndrome (CS - PTEN), Li-Fraumeni Syndrome (LFS - TP53), Peutz-Jegher Syndrome (PJS - STK11), Neurofibromatosis T …
Hereditary cancer susceptibility syndromes, including Hereditary Breast and Ovarian Cancer Syndrome (HBOC - BRCA1/2), Cowden Syndr
Genetic Predisposition to Colorectal Cancer: How Many and Which Genes to Test?
Rebuzzi F, Ulivi P, Tedaldi G. Rebuzzi F, et al. Int J Mol Sci. 2023 Jan 21;24(3):2137. doi: 10.3390/ijms24032137. Int J Mol Sci. 2023. PMID: 36768460 Free PMC article. Review.
Colorectal cancer is one of the most common tumors, and genetic predisposition is one of the key risk factors in the development of this malignancy. Lynch syndrome and familial adenomatous polyposis are the best-known genetic diseases associated with hereditary colorectal …
Colorectal cancer is one of the most common tumors, and genetic predisposition is one of the key risk factors in the development of this mal …
390 results