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2025

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1989 1
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2025 0

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Page 1
Plasma citrulline level as a biomarker for cancer therapy-induced small bowel mucosal damage.
Barzał JA, Szczylik C, Rzepecki P, Jaworska M, Anuszewska E. Barzał JA, et al. Acta Biochim Pol. 2014;61(4):615-31. Epub 2014 Dec 4. Acta Biochim Pol. 2014. PMID: 25473654 Review.
One of potential non-invasive biomarkers of gastrointestinal mucosal damage is plasma citrulline level. Citrulline is an amino acid produced by small bowel enterocytes. Low concentration of free circulating citrulline signifies severe intestinal …
One of potential non-invasive biomarkers of gastrointestinal mucosal damage is plasma citrulline level. Citrulline is a …
Amino acid metabolism in uremia.
Fürst P. Fürst P. J Am Coll Nutr. 1989 Aug;8(4):310-23. doi: 10.1080/07315724.1989.10720307. J Am Coll Nutr. 1989. PMID: 2674258 Review.
There are also grossly abnormal amino acid levels in the plasma of uremic patients, e.g., increases in conjugated amino acids, high levels of several nonessential and low levels of essential amino acids. ...In chronic renal failure patients, the intracellular concen …
There are also grossly abnormal amino acid levels in the plasma of uremic patients, e.g., increases in conjugated amino acids, high l …
Acute intestinal failure in critically ill patients: is plasma citrulline the right marker?
Piton G, Manzon C, Cypriani B, Carbonnel F, Capellier G. Piton G, et al. Intensive Care Med. 2011 Jun;37(6):911-7. doi: 10.1007/s00134-011-2172-x. Epub 2011 Mar 12. Intensive Care Med. 2011. PMID: 21400011 Review.
On the other hand, systemic inflammatory response syndrome (SIRS) and sepsis could be linked to an acute dysfunction of enterocytes without enterocyte reduction. Citrulline is an amino acid mainly synthesized by small bowel enterocytes. Various contexts of chronic and acut …
On the other hand, systemic inflammatory response syndrome (SIRS) and sepsis could be linked to an acute dysfunction of enterocytes without …
[Treatment and Pathomechanism of Citrin Deficiency].
Hayasaka K, Numakura C, Watanabe H. Hayasaka K, et al. Brain Nerve. 2015 Jun;67(6):739-47. doi: 10.11477/mf.1416200211. Brain Nerve. 2015. PMID: 26062589 Review. Japanese.
We extended this therapy for CTLN2 and found that an MCT supplementation therapy under a low-carbohydrate formula prevented the relapse of hyperammonemic encephalopathy, normalized the liver dysfunction (including the Fisher ratio), and gradually improved the level of p
We extended this therapy for CTLN2 and found that an MCT supplementation therapy under a low-carbohydrate formula prevented the relap …
Pharmacokinetics of arginine and related amino acids.
Cynober L. Cynober L. J Nutr. 2007 Jun;137(6 Suppl 2):1646S-1649S. doi: 10.1093/jn/137.6.1646S. J Nutr. 2007. PMID: 17513441 Free article. Review.
Arginine (ARG) and its related amino acids (AAs) ornithine (ORN) and citrulline (CIT) find a range of applications as dietary supplements in subgroups of healthy subjects (e.g., bodybuilders) and patients with acute or chronic malnutrition. These AAs appear to be well util …
Arginine (ARG) and its related amino acids (AAs) ornithine (ORN) and citrulline (CIT) find a range of applications as dietary supplem …
[Novel immunodiagnostics for inflammatory arthritis].
Wahle M, Kling E. Wahle M, et al. Z Rheumatol. 2016 May;75(4):361-6. doi: 10.1007/s00393-016-0090-6. Z Rheumatol. 2016. PMID: 27142378 Review. German.
The detection of antibodies against citrullinated proteins has significantly improved the immunodiagnostics of arthritis, whereas the importance of testing for rheumatoid factor has decreased due to the low specificity. ...In contrast, the determination of cytokine …
The detection of antibodies against citrullinated proteins has significantly improved the immunodiagnostics of arthritis, whereas the …
Glutamine alimentation in catabolic state.
Boelens PG, Nijveldt RJ, Houdijk AP, Meijer S, van Leeuwen PA. Boelens PG, et al. J Nutr. 2001 Sep;131(9 Suppl):2569S-77S; discussion 2590S. doi: 10.1093/jn/131.9.2569S. J Nutr. 2001. PMID: 11533315 Review.
Glutamine should be reclassified as a conditionally essential amino acid in the catabolic state because the body's glutamine expenditures exceed synthesis and low glutamine levels in plasma are associated with poor clinical outcome. After severe stress, several amin …
Glutamine should be reclassified as a conditionally essential amino acid in the catabolic state because the body's glutamine expenditures ex …
Lysinuric protein intolerance: reviewing concepts on a multisystem disease.
Sebastio G, Sperandeo MP, Andria G. Sebastio G, et al. Am J Med Genet C Semin Med Genet. 2011 Feb 15;157C(1):54-62. doi: 10.1002/ajmg.c.30287. Epub 2011 Feb 9. Am J Med Genet C Semin Med Genet. 2011. PMID: 21308987 Review.
This condition is diagnosed by urine amino acids, showing markedly elevated excretion of lysine and other dibasic amino acids despite low plasma levels of lysine, ornithine, and arginine. The biochemical diagnosis can be uncertain, requiring confirmation by DNA test …
This condition is diagnosed by urine amino acids, showing markedly elevated excretion of lysine and other dibasic amino acids despite low
ADMA: a novel risk factor that explains excess cardiovascular event rate in patients with end-stage renal disease.
Böger RH, Zoccali C. Böger RH, et al. Atheroscler Suppl. 2003 Dec;4(4):23-8. doi: 10.1016/s1567-5688(03)00030-8. Atheroscler Suppl. 2003. PMID: 14664899 Review.
ADMA, like its biologically inactive regioisomer, symmetric dimethylarginine (SDMA), can be found in human plasma and urine in low concentrations. The concentrations of both dimethylarginines are increased in patients with end-stage renal disease, which may explain …
ADMA, like its biologically inactive regioisomer, symmetric dimethylarginine (SDMA), can be found in human plasma and urine in low
Relationship of asymmetric dimethylarginine to dialysis treatment and atherosclerotic disease.
Kielstein JT, Bode-Böger SM, Frölich JC, Haller H, Böger RH. Kielstein JT, et al. Kidney Int Suppl. 2001 Feb;78:S9-13. doi: 10.1046/j.1523-1755.2001.59780009.x. Kidney Int Suppl. 2001. PMID: 11168975 Free article. Review.
In addition, ADMA is degraded by the enzyme dimethylarginine dimethylaminohydrolase (DDAH), which hydrolyzes ADMA to L-citrulline and dimethylamine. Activity of DDAH is decreased by oxidized low density lipoprotein (LDL) or tumor necrosis factor-alpha (TNF-alpha) in …
In addition, ADMA is degraded by the enzyme dimethylarginine dimethylaminohydrolase (DDAH), which hydrolyzes ADMA to L-citrulline and …
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