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Page 1
Primary biliary cholangitis: pathogenic mechanisms.
Prieto J, Banales JM, Medina JF. Prieto J, et al. Curr Opin Gastroenterol. 2021 Mar 1;37(2):91-98. doi: 10.1097/MOG.0000000000000703. Curr Opin Gastroenterol. 2021. PMID: 33332913 Free PMC article. Review.
PURPOSE OF REVIEW: Primary biliary cholangitis (PBC) is characterized by autoimmune damage of intrahepatic bile ducts associated with a loss of tolerance to mitochondrial antigens. ...RECENT FINDINGS: PBC develops in patients with genetic predisposition to autoimmunity in …
PURPOSE OF REVIEW: Primary biliary cholangitis (PBC) is characterized by autoimmune damage of intrahepatic bile ducts associated with …
Is PBC a viral infectious disease?
Mason AL. Mason AL. Best Pract Res Clin Gastroenterol. 2018 Jun-Aug;34-35:27-39. doi: 10.1016/j.bpg.2018.06.001. Epub 2018 Jun 14. Best Pract Res Clin Gastroenterol. 2018. PMID: 30343707 Review.
The human betaretrovirus and the closely related mouse mammary tumor virus have been linked with the development of cholangitis and mitochondrial antibody production in patients with primary biliary cholangitis (PBC) and mouse models of autoimmune biliary disease, r …
The human betaretrovirus and the closely related mouse mammary tumor virus have been linked with the development of cholangitis and m …
Liver and apoptosis.
Valente M, Calabrese F. Valente M, et al. Ital J Gastroenterol Hepatol. 1999 Jan-Feb;31(1):73-7. Ital J Gastroenterol Hepatol. 1999. PMID: 10091108 Review.
Apoptosis is an energy-requiring mechanism of cell death which is a physiological event in organ morphogenesis, clone selection of lymphoid cells and cell turnover, but also occurs in many pathological conditions. ...The Fas/Fas1 system is also involved in apoptosis occurr …
Apoptosis is an energy-requiring mechanism of cell death which is a physiological event in organ morphogenesis, clone selection of lympho …
Mechanisms of autoimmune liver disease.
Baier JL, Mattner J. Baier JL, et al. Discov Med. 2014 Nov;18(100):255-63. Discov Med. 2014. PMID: 25425466 Free article. Review.
Thus, next to tissue-specific factors, general tolerance mechanisms are affected in devastating hepatic disorders like primary sclerosing cholangitis (PSC), autoimmune hepatitis (AIH), or primary biliary cirrhosis (PBC). The innate immune cell populations abundantly detect …
Thus, next to tissue-specific factors, general tolerance mechanisms are affected in devastating hepatic disorders like primary sclerosing …
Immunopathogenesis of gastrointestinal and hepatobiliary diseases.
Galperin C, Gershwin ME. Galperin C, et al. JAMA. 1997 Dec 10;278(22):1946-55. JAMA. 1997. PMID: 9396657 Review.
The largest lymphoid organ in the body is the gut and the gut-associated lymphoid tissue. ...In addition, the mucosal immune system plays a role in inflammatory bowel disease, Whipple disease, autoimmune gastritis, Helicobacter pylori infection, immunoproliferative …
The largest lymphoid organ in the body is the gut and the gut-associated lymphoid tissue. ...In addition, the mucosal immune s …
Liver abnormalities in connective tissue diseases.
De Santis M, Crotti C, Selmi C. De Santis M, et al. Best Pract Res Clin Gastroenterol. 2013 Aug;27(4):543-51. doi: 10.1016/j.bpg.2013.06.016. Best Pract Res Clin Gastroenterol. 2013. PMID: 24090941 Review.
The liver is a lymphoid organ involved in the immune response and in the maintenance of tolerance to self molecules, but it is also a target of autoimmune reactions, as observed in primary liver autoimmune diseases (AILD) such as autoimmune hepatitis, primary biliary cirrh …
The liver is a lymphoid organ involved in the immune response and in the maintenance of tolerance to self molecules, but it is also a …
Liver auto-immunology: the paradox of autoimmunity in a tolerogenic organ.
Invernizzi P. Invernizzi P. J Autoimmun. 2013 Oct;46:1-6. doi: 10.1016/j.jaut.2013.08.006. Epub 2013 Sep 5. J Autoimmun. 2013. PMID: 24012346 Free article. Review.
The study of the liver as a lymphoid organ is a growing field fueled by our better knowledge of the different component of the immune system and how they orchestrate an immune-related response. The liver have highly specialized mechanisms of immune tolerance, mainly becaus …
The study of the liver as a lymphoid organ is a growing field fueled by our better knowledge of the different component of the immune …
The lymphoid liver: considerations on pathways to autoimmune injury.
Kita H, Mackay IR, Van De Water J, Gershwin ME. Kita H, et al. Gastroenterology. 2001 May;120(6):1485-501. doi: 10.1053/gast.2001.22441. Gastroenterology. 2001. PMID: 11313320 Review.
Immunologic injury in the liver involves immigrant T and B lymphocytes and a resident lymphoid population that comprises distinct lymphocytic cells and accessory cells. ...
Immunologic injury in the liver involves immigrant T and B lymphocytes and a resident lymphoid population that comprises distinct lym …
Autoimmune features in metabolic liver disease: a single-center experience and review of the literature.
Tsuneyama K, Baba H, Kikuchi K, Nishida T, Nomoto K, Hayashi S, Miwa S, Nakajima T, Nakanishi Y, Masuda S, Terada M, Imura J, Selmi C. Tsuneyama K, et al. Clin Rev Allergy Immunol. 2013 Aug;45(1):143-8. doi: 10.1007/s12016-013-8383-x. Clin Rev Allergy Immunol. 2013. PMID: 23842720 Review.
In one third of mice, regardless of the model, we observed a marked lymphoid infiltrate with non-suppurative cholangitis, and several cases were ANA-positive, but none AMA-positive. ...
In one third of mice, regardless of the model, we observed a marked lymphoid infiltrate with non-suppurative cholangitis, and …
Radiology of AIDS in the pediatric patient.
Grattan-Smith D, Harrison LF, Singleton EB. Grattan-Smith D, et al. Curr Probl Diagn Radiol. 1992 May-Jun;21(3):79-109. doi: 10.1016/0363-0188(92)90038-h. Curr Probl Diagn Radiol. 1992. PMID: 1576831 Review.
The most common pulmonary complications in our experience are Pneumocystis carinii pneumonia and pulmonary lymphoid hyperplasia. The spectrum of cardiovascular involvement in pediatric AIDS includes myocarditis, pericarditis, and infectious endocarditis. ...Abdominal lymph …
The most common pulmonary complications in our experience are Pneumocystis carinii pneumonia and pulmonary lymphoid hyperplasia. The …
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