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1963
2025

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 18
1964 38
1965 16
1966 21
1967 34
1968 37
1969 56
1970 75
1971 67
1972 87
1973 72
1974 133
1975 100
1976 112
1977 124
1978 156
1979 108
1980 106
1981 77
1982 79
1983 133
1984 136
1985 127
1986 132
1987 175
1988 294
1989 331
1990 395
1991 413
1992 430
1993 474
1994 545
1995 513
1996 656
1997 627
1998 586
1999 644
2000 813
2001 837
2002 784
2003 943
2004 990
2005 932
2006 1059
2007 1157
2008 1178
2009 1196
2010 1294
2011 1419
2012 1474
2013 1532
2014 1782
2015 1788
2016 1871
2017 1836
2018 1731
2019 1684
2020 1805
2021 1555
2022 933
2023 883
2024 1164
2025 52

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37,642 results

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Page 1
Metastasis.
Gerstberger S, Jiang Q, Ganesh K. Gerstberger S, et al. Cell. 2023 Apr 13;186(8):1564-1579. doi: 10.1016/j.cell.2023.03.003. Cell. 2023. PMID: 37059065 Free PMC article. Review.
Most cancer-associated deaths occur due to metastasis, yet our understanding of metastasis as an evolving, heterogeneous, systemic disease and of how to effectively treat it is still emerging. ...Here, we review the main principles of metastasis and highlight …
Most cancer-associated deaths occur due to metastasis, yet our understanding of metastasis as an evolving, heterogeneous, syst …
Targeting metastatic cancer.
Ganesh K, Massagué J. Ganesh K, et al. Nat Med. 2021 Jan;27(1):34-44. doi: 10.1038/s41591-020-01195-4. Epub 2021 Jan 13. Nat Med. 2021. PMID: 33442008 Free PMC article. Review.
Despite recent therapeutic advances in cancer treatment, metastasis remains the principal cause of cancer death. Recent work has uncovered the unique biology of metastasis-initiating cells that results in tumor growth in distant organs, evasion of immune surveillanc …
Despite recent therapeutic advances in cancer treatment, metastasis remains the principal cause of cancer death. Recent work has unco …
Molecular principles of metastasis: a hallmark of cancer revisited.
Fares J, Fares MY, Khachfe HH, Salhab HA, Fares Y. Fares J, et al. Signal Transduct Target Ther. 2020 Mar 12;5(1):28. doi: 10.1038/s41392-020-0134-x. Signal Transduct Target Ther. 2020. PMID: 32296047 Free PMC article. Review.
Metastasis is the hallmark of cancer that is responsible for the greatest number of cancer-related deaths. ...Establishing the biological mechanisms of the metastatic process is crucial in finding open therapeutic windows for successful interventions. ...
Metastasis is the hallmark of cancer that is responsible for the greatest number of cancer-related deaths. ...Establishing the biolog
Bone metastases.
Coleman RE, Croucher PI, Padhani AR, Clézardin P, Chow E, Fallon M, Guise T, Colangeli S, Capanna R, Costa L. Coleman RE, et al. Nat Rev Dis Primers. 2020 Oct 15;6(1):83. doi: 10.1038/s41572-020-00216-3. Nat Rev Dis Primers. 2020. PMID: 33060614 Review.
Bone is the most frequent site for metastasis for many cancers, notably for tumours originating in the breast and the prostate. ...Within the bone, these disseminated tumour cells, as well as those arising in the context of multiple myeloma, may assume a state of dormancy, …
Bone is the most frequent site for metastasis for many cancers, notably for tumours originating in the breast and the prostate. ...Wi …
Pre-metastatic niches: organ-specific homes for metastases.
Peinado H, Zhang H, Matei IR, Costa-Silva B, Hoshino A, Rodrigues G, Psaila B, Kaplan RN, Bromberg JF, Kang Y, Bissell MJ, Cox TR, Giaccia AJ, Erler JT, Hiratsuka S, Ghajar CM, Lyden D. Peinado H, et al. Nat Rev Cancer. 2017 May;17(5):302-317. doi: 10.1038/nrc.2017.6. Epub 2017 Mar 17. Nat Rev Cancer. 2017. PMID: 28303905 Review.
It is well established that organs of future metastasis are not passive receivers of circulating tumour cells, but are instead selectively and actively modified by the primary tumour before metastatic spread has even occurred. Sowing the 'seeds' of metastasis
It is well established that organs of future metastasis are not passive receivers of circulating tumour cells, but are instead select …
Tumor metastasis: molecular insights and evolving paradigms.
Valastyan S, Weinberg RA. Valastyan S, et al. Cell. 2011 Oct 14;147(2):275-92. doi: 10.1016/j.cell.2011.09.024. Cell. 2011. PMID: 22000009 Free PMC article. Review.
Metastases represent the end products of a multistep cell-biological process termed the invasion-metastasis cascade, which involves dissemination of cancer cells to anatomically distant organ sites and their subsequent adaptation to foreign tissue microenvironments. Each o …
Metastases represent the end products of a multistep cell-biological process termed the invasion-metastasis cascade, which involves d …
Metastatic Breast Cancer.
Peart O. Peart O. Radiol Technol. 2017 May;88(5):519M-539M. Radiol Technol. 2017. PMID: 28500107 Review.
No cure for metastatic breast cancer yet exists, and it is associated with a poor prognosis: The 5-year survival rate is 26%. ...It also discusses the molecular subtypes of breast cancer, symptoms of metastatic breast cancer, and current treatments for the disease.. …
No cure for metastatic breast cancer yet exists, and it is associated with a poor prognosis: The 5-year survival rate is 26%. ...It a …
Metastatic colonization by circulating tumour cells.
Massagué J, Obenauf AC. Massagué J, et al. Nature. 2016 Jan 21;529(7586):298-306. doi: 10.1038/nature17038. Nature. 2016. PMID: 26791720 Free PMC article. Review.
Metastasis is the main cause of death in people with cancer. To colonize distant organs, circulating tumour cells must overcome many obstacles through mechanisms that we are only now starting to understand. ...An improved understanding of the mechanistic determinants of su
Metastasis is the main cause of death in people with cancer. To colonize distant organs, circulating tumour cells must overcome many
On the origin of cancer metastasis.
Seyfried TN, Huysentruyt LC. Seyfried TN, et al. Crit Rev Oncog. 2013;18(1-2):43-73. doi: 10.1615/critrevoncog.v18.i1-2.40. Crit Rev Oncog. 2013. PMID: 23237552 Free PMC article. Review.
Many of the properties of metastatic cancer cells are also seen in normal macrophages. A macrophage origin of metastasis can also explain the long-standing "seed and soil" hypothesis and the absence of metastasis in plant cancers. The view of metastasis
Many of the properties of metastatic cancer cells are also seen in normal macrophages. A macrophage origin of metastasis can a …
Metastasis as an evolutionary process.
Turajlic S, Swanton C. Turajlic S, et al. Science. 2016 Apr 8;352(6282):169-75. doi: 10.1126/science.aaf2784. Science. 2016. PMID: 27124450 Review.
Therapeutic advances in oncology have not fully translated to the treatment of metastatic disease, which remains largely incurable. Metastatic subclones can emerge both early and late in the life of the primary tumor. A better understanding of the genetic evolution …
Therapeutic advances in oncology have not fully translated to the treatment of metastatic disease, which remains largely incurable. …
37,642 results
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