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Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome.
Prog Neurobiol. 2013 Jul-Aug;106-107:33-54. doi: 10.1016/j.pneurobio.2013.06.002. Epub 2013 Jul 1.
Prog Neurobiol. 2013.
PMID: 23827971
Review.
Recent studies have indicated that the expression Beclin 1 is reduced in AD brain. Moreover, the deficiency of Beclin 1 in cultured neurons and transgenic mice provokes the deposition of amyloid-beta peptides whereas its overexpression reduces the accumulatio …
Recent studies have indicated that the expression Beclin 1 is reduced in AD brain. Moreover, the deficiency of Beclin 1 …
Nuclear gene defects in mitochondrial disorders.
Zeviani M, Corona P, Nijtmans L, Tiranti V.
Zeviani M, et al.
Ital J Neurol Sci. 1999 Dec;20(6):401-8. doi: 10.1007/s100720050059.
Ital J Neurol Sci. 1999.
PMID: 10937860
Review.
An increasing number of nuclear genes have been associated with abnormalities of oxidative phosphorylation and mitochondrial disorders. ...Loss-of-function mutations in SURF-1, a gene belonging to the third category, have been associated with Leigh syndrome w …
An increasing number of nuclear genes have been associated with abnormalities of oxidative phosphorylation and mitochondrial d …
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