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Year Number of Results
1987 2
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1993 1
1995 4
1996 1
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2002 2
2003 3
2005 3
2006 1
2007 2
2009 4
2010 3
2011 2
2012 3
2013 3
2014 2
2015 3
2016 4
2017 3
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2023 2
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63 results

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Page 1
The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia.
Arber DA, Orazi A, Hasserjian R, Thiele J, Borowitz MJ, Le Beau MM, Bloomfield CD, Cazzola M, Vardiman JW. Arber DA, et al. Blood. 2016 May 19;127(20):2391-405. doi: 10.1182/blood-2016-03-643544. Epub 2016 Apr 11. Blood. 2016. PMID: 27069254 Free article. Review.
Since then, there have been numerous advances in the identification of unique biomarkers associated with some myeloid neoplasms and acute leukemias, largely derived from gene expression analysis and next-generation sequencing that can significantly improve the diagn …
Since then, there have been numerous advances in the identification of unique biomarkers associated with some myeloid neoplasm …
Management of Down Syndrome-Associated Leukemias: A Review.
Verma A, Lupo PJ, Shah NN, Hitzler J, Rabin KR. Verma A, et al. JAMA Oncol. 2023 Sep 1;9(9):1283-1290. doi: 10.1001/jamaoncol.2023.2163. JAMA Oncol. 2023. PMID: 37440251 Review.
IMPORTANCE: Down syndrome (DS), caused by an extra copy of material from chromosome 21, is one of the most common genetic conditions. ...After a latency period of up to 4 years, 20% to 30% develop myeloid leukemia associated with DS (ML-DS). Rec …
IMPORTANCE: Down syndrome (DS), caused by an extra copy of material from chromosome 21, is one of the most common genetic cond …
Neonatal Leukemia.
Brown PA. Brown PA. Clin Perinatol. 2021 Mar;48(1):15-33. doi: 10.1016/j.clp.2020.11.002. Clin Perinatol. 2021. PMID: 33583502 Review.
Neonates are at risk for 3 major forms of leukemia in the first year of life: acute leukemia, juvenile myelomonocytic leukemia, and transient abnormal myelopoiesis associated with Down syndrome. ...
Neonates are at risk for 3 major forms of leukemia in the first year of life: acute leukemia, juvenile myelomonocytic leuke …
The International Consensus Classification (ICC) of hematologic neoplasms with germline predisposition, pediatric myelodysplastic syndrome, and juvenile myelomonocytic leukemia.
Rudelius M, Weinberg OK, Niemeyer CM, Shimamura A, Calvo KR. Rudelius M, et al. Virchows Arch. 2023 Jan;482(1):113-130. doi: 10.1007/s00428-022-03447-9. Epub 2022 Nov 29. Virchows Arch. 2023. PMID: 36445482 Review.
Updating the classification of hematologic neoplasia with germline predisposition, pediatric myelodysplastic syndrome (MDS), and juvenile myelomonocytic leukemia (JMML) is critical for diagnosis, therapy, research, and clinical trials. ...Genes are organized into th …
Updating the classification of hematologic neoplasia with germline predisposition, pediatric myelodysplastic syndrome (MDS), and juve …
Neonatal leukaemia.
Roberts I, Fordham NJ, Rao A, Bain BJ. Roberts I, et al. Br J Haematol. 2018 Jul;182(2):170-184. doi: 10.1111/bjh.15246. Epub 2018 May 28. Br J Haematol. 2018. PMID: 29806701 Free article. Review.
Neonatal leukaemia is defined as occurring within the first 28 days of life and most, if not all, cases are congenital. With the exception of Down syndrome-associated transient abnormal myelopoiesis, which is not considered here, neonatal leukaemias are rare. …
Neonatal leukaemia is defined as occurring within the first 28 days of life and most, if not all, cases are congenital. With the exception o …
Morphological and Immunophenotypic Clues to the WHO Categories of Acute Myeloid Leukaemia.
Bain BJ, Béné MC. Bain BJ, et al. Acta Haematol. 2019;141(4):232-244. doi: 10.1159/000496097. Epub 2019 Apr 9. Acta Haematol. 2019. PMID: 30965338 Free article. Review.
Diagnosis and classification of acute myeloid leukaemia (AML) require cytogenetic and molecular genetic investigation. ...In addition, transient abnormal myelopoiesis of Down's syndrome can generally be diagnosed morphologically....
Diagnosis and classification of acute myeloid leukaemia (AML) require cytogenetic and molecular genetic investigation. ...In a …
The paradox of Myeloid Leukemia associated with Down syndrome.
Gupte A, Al-Antary ET, Edwards H, Ravindranath Y, Ge Y, Taub JW. Gupte A, et al. Biochem Pharmacol. 2022 Jul;201:115046. doi: 10.1016/j.bcp.2022.115046. Epub 2022 Apr 26. Biochem Pharmacol. 2022. PMID: 35483417 Review.
Children with Down syndrome constitute a distinct genetic population who has a greater risk of developing acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) compared to their non-Down syndrome counterparts. ...Vari …
Children with Down syndrome constitute a distinct genetic population who has a greater risk of developing acute lymphoblastic …
Cohesin mutations in myeloid malignancies.
Jann JC, Tothova Z. Jann JC, et al. Blood. 2021 Aug 26;138(8):649-661. doi: 10.1182/blood.2019004259. Blood. 2021. PMID: 34157074 Free PMC article. Review.
The core complex subunits STAG2, RAD21, SMC1, and SMC3, as well as its modulators PDS5A/B, WAPL, and NIPBL, have been found to be recurrently mutated in hematologic and solid malignancies. These mutations are found across the full spectrum of myeloid neoplasia, including p …
The core complex subunits STAG2, RAD21, SMC1, and SMC3, as well as its modulators PDS5A/B, WAPL, and NIPBL, have been found to be recurrentl …
Transient leukemia of Down syndrome.
Sas V, Blag C, Zaharie G, Puscas E, Lisencu C, Andronic-Gorcea N, Pasca S, Petrushev B, Chis I, Marian M, Dima D, Teodorescu P, Iluta S, Zdrenghea M, Berindan-Neagoe I, Popa G, Man S, Colita A, Stefan C, Kojima S, Tomuleasa C. Sas V, et al. Crit Rev Clin Lab Sci. 2019 Jun;56(4):247-259. doi: 10.1080/10408363.2019.1613629. Epub 2019 Jun 21. Crit Rev Clin Lab Sci. 2019. PMID: 31043105 Review.
The World Health Organization defines transient leukemia of Down syndrome (DS) as increased peripheral blood blasts in neonates with DS and classifies this type of leukemia as a separate entity. Although it was shown that DS predisposes children to …
The World Health Organization defines transient leukemia of Down syndrome (DS) as increased peripheral blood blasts in …
Predispositions to Leukemia in Down Syndrome and Other Hereditary Disorders.
Saida S. Saida S. Curr Treat Options Oncol. 2017 Jul;18(7):41. doi: 10.1007/s11864-017-0485-x. Curr Treat Options Oncol. 2017. PMID: 28580501 Review.
Leukemia is the most common pediatric cancer and accounts for approximately one third of childhood malignancies. ...These predispositions to cancer syndromes can be attributed to DNA repair/genetic instability, RAS pathway dysfunction, bone marrow failure, telomeropathies, …
Leukemia is the most common pediatric cancer and accounts for approximately one third of childhood malignancies. ...These predisposit …
63 results