Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1964 2
1967 2
1968 1
1969 3
1971 2
1972 7
1973 4
1974 5
1975 6
1976 6
1977 3
1978 3
1979 4
1980 4
1981 3
1982 8
1983 1
1984 4
1985 13
1986 3
1987 6
1988 14
1989 13
1990 26
1991 17
1992 21
1993 31
1994 31
1995 56
1996 31
1997 37
1998 20
1999 29
2000 44
2001 32
2002 47
2003 50
2004 67
2005 73
2006 83
2007 59
2008 72
2009 93
2010 98
2011 106
2012 138
2013 118
2014 140
2015 168
2016 203
2017 208
2018 174
2019 196
2020 238
2021 254
2022 207
2023 191
2024 82

Text availability

Article attribute

Article type

Publication date

Search Results

3,189 results

Results by year

Filters applied: . Clear all
Page 1
Cardiac fibrosis.
Frangogiannis NG. Frangogiannis NG. Cardiovasc Res. 2021 May 25;117(6):1450-1488. doi: 10.1093/cvr/cvaa324. Cardiovasc Res. 2021. PMID: 33135058 Free PMC article. Review.
Myocardial fibrosis, the expansion of the cardiac interstitium through deposition of extracellular matrix proteins, is a common pathophysiologic companion of many different myocardial conditions. ...Development of fibrosis-targeting therapies for patie
Myocardial fibrosis, the expansion of the cardiac interstitium through deposition of extracellular matrix proteins, is a commo
Myocardial Interstitial Fibrosis in Heart Failure: Biological and Translational Perspectives.
González A, Schelbert EB, Díez J, Butler J. González A, et al. J Am Coll Cardiol. 2018 Apr 17;71(15):1696-1706. doi: 10.1016/j.jacc.2018.02.021. J Am Coll Cardiol. 2018. PMID: 29650126 Free article. Review.
Myocardial interstitial fibrosis contributes to left ventricular dysfunction leading to the development of heart failure. ...This is partly related to the paucity of biomarkers to accurately identify myocardial interstitial fibrosis and to the lack of
Myocardial interstitial fibrosis contributes to left ventricular dysfunction leading to the development of heart failure. ...T
Cardiac fibrosis: Myofibroblast-mediated pathological regulation and drug delivery strategies.
Liu M, López de Juan Abad B, Cheng K. Liu M, et al. Adv Drug Deliv Rev. 2021 Jun;173:504-519. doi: 10.1016/j.addr.2021.03.021. Epub 2021 Apr 5. Adv Drug Deliv Rev. 2021. PMID: 33831476 Free PMC article. Review.
Cardiac fibrosis remains an unresolved problem in heart diseases. After initial injury, cardiac fibroblasts (CFs) are activated and subsequently differentiate into myofibroblasts (myoFbs) that are major mediator cells in the pathological remodeling. ...The anti-fibrotic tr …
Cardiac fibrosis remains an unresolved problem in heart diseases. After initial injury, cardiac fibroblasts (CFs) are activated and s …
Diffuse myocardial fibrosis: mechanisms, diagnosis and therapeutic approaches.
López B, Ravassa S, Moreno MU, José GS, Beaumont J, González A, Díez J. López B, et al. Nat Rev Cardiol. 2021 Jul;18(7):479-498. doi: 10.1038/s41569-020-00504-1. Epub 2021 Feb 10. Nat Rev Cardiol. 2021. PMID: 33568808 Review.
Diffuse myocardial fibrosis resulting from the excessive deposition of collagen fibres through the entire myocardium is encountered in a number of chronic cardiac diseases. ...In this regard, findings from the past 20 years suggest that various clinicopatholo …
Diffuse myocardial fibrosis resulting from the excessive deposition of collagen fibres through the entire myocardium is …
Inflammasomes and Fibrosis.
Zhang WJ, Chen SJ, Zhou SC, Wu SZ, Wang H. Zhang WJ, et al. Front Immunol. 2021 Jun 11;12:643149. doi: 10.3389/fimmu.2021.643149. eCollection 2021. Front Immunol. 2021. PMID: 34177893 Free PMC article. Review.
Fibrosis is the final common pathway of inflammatory diseases in various organs. The inflammasomes play an important role in the progression of fibrosis as innate immune receptors. There are four main members of the inflammasomes, such as NOD-like receptor protein 1
Fibrosis is the final common pathway of inflammatory diseases in various organs. The inflammasomes play an important role in the prog
Extracellular matrix remodeling and cardiac fibrosis.
Li L, Zhao Q, Kong W. Li L, et al. Matrix Biol. 2018 Aug;68-69:490-506. doi: 10.1016/j.matbio.2018.01.013. Epub 2018 Jan 31. Matrix Biol. 2018. PMID: 29371055 Review.
Cardiac fibrosis, characterized by excessive deposition of extracellular matrix (ECM) proteins in the myocardium, distorts the architecture of the myocardium, facilitates the progression of arrhythmia and cardiac dysfunction, and influences the clinical cours …
Cardiac fibrosis, characterized by excessive deposition of extracellular matrix (ECM) proteins in the myocardium, distorts the …
Redefining the identity of cardiac fibroblasts.
Tallquist MD, Molkentin JD. Tallquist MD, et al. Nat Rev Cardiol. 2017 Aug;14(8):484-491. doi: 10.1038/nrcardio.2017.57. Epub 2017 Apr 24. Nat Rev Cardiol. 2017. PMID: 28436487 Free PMC article. Review.
In the adult heart, activated cardiac fibroblasts also participate in the healing response after acute myocardial infarction and during chronic disease states characterized by augmented interstitial fibrosis and ventricular remodelling. ...As our understanding of ca …
In the adult heart, activated cardiac fibroblasts also participate in the healing response after acute myocardial infarction and duri …
The Biological Basis for Cardiac Repair After Myocardial Infarction: From Inflammation to Fibrosis.
Prabhu SD, Frangogiannis NG. Prabhu SD, et al. Circ Res. 2016 Jun 24;119(1):91-112. doi: 10.1161/CIRCRESAHA.116.303577. Circ Res. 2016. PMID: 27340270 Free PMC article. Review.
In adult mammals, massive sudden loss of cardiomyocytes after infarction overwhelms the limited regenerative capacity of the myocardium, resulting in the formation of a collagen-based scar. Necrotic cells release danger signals, activating innate immune pathways and trigge …
In adult mammals, massive sudden loss of cardiomyocytes after infarction overwhelms the limited regenerative capacity of the myocardium
Role of Cardiac Macrophages on Cardiac Inflammation, Fibrosis and Tissue Repair.
Lafuse WP, Wozniak DJ, Rajaram MVS. Lafuse WP, et al. Cells. 2020 Dec 31;10(1):51. doi: 10.3390/cells10010051. Cells. 2020. PMID: 33396359 Free PMC article. Review.
Cardiac inflammation and subsequent tissue damage is orchestrated by the infiltration and activation of various immune cells including neutrophils, monocytes, macrophages, eosinophils, mast cells, natural killer cells, and T and B cells into the myocardium. After tissue in …
Cardiac inflammation and subsequent tissue damage is orchestrated by the infiltration and activation of various immune cells including neutr …
The pathogenesis of cardiac fibrosis.
Kong P, Christia P, Frangogiannis NG. Kong P, et al. Cell Mol Life Sci. 2014 Feb;71(4):549-74. doi: 10.1007/s00018-013-1349-6. Epub 2013 May 7. Cell Mol Life Sci. 2014. PMID: 23649149 Free PMC article. Review.
Cardiac fibrosis is characterized by net accumulation of extracellular matrix proteins in the cardiac interstitium, and contributes to both systolic and diastolic dysfunction in many cardiac pathophysiologic conditions. ...Understanding the mechanisms responsible for initi …
Cardiac fibrosis is characterized by net accumulation of extracellular matrix proteins in the cardiac interstitium, and contributes t …
3,189 results