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Role of vasopressin antagonists.
Torres VE. Torres VE. Clin J Am Soc Nephrol. 2008 Jul;3(4):1212-8. doi: 10.2215/CJN.05281107. Epub 2008 Apr 23. Clin J Am Soc Nephrol. 2008. PMID: 18434616 Review.
The arginine vasopressin V2 receptor antagonists OPC-31260 and tolvaptan inhibit the development of polycystic kidney disease in cpk mice and in three animal orthologs to human autosomal recessive polycystic kidney disease (PCK rat), autosomal dominant polycystic kidney disease ( …
The arginine vasopressin V2 receptor antagonists OPC-31260 and tolvaptan inhibit the development of polycystic kidney disease in cpk mice an …
Nephronophthisis-associated ciliopathies.
Hildebrandt F, Zhou W. Hildebrandt F, et al. J Am Soc Nephrol. 2007 Jun;18(6):1855-71. doi: 10.1681/ASN.2006121344. Epub 2007 May 18. J Am Soc Nephrol. 2007. PMID: 17513324 Review.
Nephronophthisis (NPHP), an autosomal recessive cystic kidney disease, represents the most frequent genetic cause of end-stage kidney disease in the first three decades of life. ...
Nephronophthisis (NPHP), an autosomal recessive cystic kidney disease, represents the most frequent genetic cause of end-stage kidney …
Vasopressin antagonists in polycystic kidney disease.
Torres VE. Torres VE. Semin Nephrol. 2008 May;28(3):306-17. doi: 10.1016/j.semnephrol.2008.03.003. Semin Nephrol. 2008. PMID: 18519091 Free PMC article. Review.
The arginine vasopressin V2 receptor antagonists OPC-31260 and tolvaptan inhibit the development of polycystic kidney disease in cpk mice and in three animal orthologs to human autosomal recessive polycystic kidney disease (PCK rat), autosomal dominant polycystic kidney disease ( …
The arginine vasopressin V2 receptor antagonists OPC-31260 and tolvaptan inhibit the development of polycystic kidney disease in cpk mice an …
Inherited defects of renal basement membranes.
Noël LH, Gubler MC, Bobrie G, Savage CO, Lockwood CM, Grünfeld JP. Noël LH, et al. Adv Nephrol Necker Hosp. 1989;18:77-94. Adv Nephrol Necker Hosp. 1989. PMID: 2493725 Review.
In the nail-patella syndrome, in Alport's syndrome and variants, and in benign familial hematuria, the changes involve the glomerular basement membrane (GBM). In nephronophthisis, the tubular basement membrane (TBM) is affected. These histopathologic features are not unifo …
In the nail-patella syndrome, in Alport's syndrome and variants, and in benign familial hematuria, the changes involve the glomerular baseme …
Approach to the evaluation of heritable diseases and update on familial focal segmental glomerulosclerosis.
Winn MP. Winn MP. Nephrol Dial Transplant. 2003 Aug;18 Suppl 6:vi14-20. doi: 10.1093/ndt/gfg1070. Nephrol Dial Transplant. 2003. PMID: 12953036 Review.
Genes associated with many familial renal disorders that lead to ESRD have been isolated; these include Alport's nephropathy, familial juvenile nephronophthisis and adult polycystic disease. Recently, the genetic mutation (ACTN4) causing a form of autosomal dominant FSGS ( …
Genes associated with many familial renal disorders that lead to ESRD have been isolated; these include Alport's nephropathy, familial juven …