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Page 1
Melanoma: Clinical Presentations.
Kibbi N, Kluger H, Choi JN. Kibbi N, et al. Cancer Treat Res. 2016;167:107-29. doi: 10.1007/978-3-319-22539-5_4. Cancer Treat Res. 2016. PMID: 26601860 Review.
The malignant cell in melanoma is the melanocyte. Because melanocytes are located in the basal layer of the epidermis, melanoma is most commonly seen on the skin. ...This chapter presents the spectrum of typical and less typical presentations of melanoma, as …
The malignant cell in melanoma is the melanocyte. Because melanocytes are located in the basal layer of the epidermis, melanoma
Genetic drivers of non-cutaneous melanomas: Challenges and opportunities in a heterogeneous landscape.
Vergara IA, Wilmott JS, Long GV, Scolyer RA. Vergara IA, et al. Exp Dermatol. 2022 Jan;31(1):13-30. doi: 10.1111/exd.14287. Epub 2021 Feb 1. Exp Dermatol. 2022. PMID: 33455025 Review.
Non-cutaneous melanomas most frequently involve the uveal tract and mucosal membranes, including the conjunctiva. ...The mutational load within most non-cutaneous melanomas reflects their lower ultraviolet light (UV) exposure. ...
Non-cutaneous melanomas most frequently involve the uveal tract and mucosal membranes, including the conjunctiva. ...Th
Non-cutaneous melanoma: is there a role for (18)F-FDG PET-CT?
Murphy G, Hussey D, Metser U. Murphy G, et al. Br J Radiol. 2014 Aug;87(1040):20140324. doi: 10.1259/bjr.20140324. Epub 2014 Jun 5. Br J Radiol. 2014. PMID: 24901893 Free PMC article. Review.
Non-cutaneous melanomas (NCM) are diverse and relatively uncommon. They often differ from cutaneous melanomas in their epidemiology, genetic profile and biological behaviour. ...
Non-cutaneous melanomas (NCM) are diverse and relatively uncommon. They often differ from cutaneous melanomas in
Melanoma Adjuvant Treatment: Current Insight and Clinical Features.
D'Aniello C, Perri F, Scarpati GDV, Pepa CD, Pisconti S, Montesarchio V, Wernert N, Zarone MR, Caraglia M, Facchini G, Berretta M, Cavaliere C. D'Aniello C, et al. Curr Cancer Drug Targets. 2018;18(5):442-456. doi: 10.2174/1568009617666170208163714. Curr Cancer Drug Targets. 2018. PMID: 28183255 Review.
Melanoma represents 2-3% of all cancers, 95% of them arise from skin, while only 5% are non-cutaneous melanoma. ...Ipilimumab represents a possible breakthrough in this setting, considering the positive results of the EORTC 18701 trials in terms of dis
Melanoma represents 2-3% of all cancers, 95% of them arise from skin, while only 5% are non-cutaneous melanoma.
Immunotherapy Options for Acral Melanoma, A fast-growing but Neglected Malignancy.
Gajón JA, Juarez-Flores A, De León Rodríguez SG, Aguilar Flores C, Mantilla A, Fuentes-Pananá EM, Bonifaz LC. Gajón JA, et al. Arch Med Res. 2022 Dec;53(8):794-806. doi: 10.1016/j.arcmed.2022.11.008. Epub 2022 Nov 30. Arch Med Res. 2022. PMID: 36460547 Review.
Melanoma is the deadliest form of skin cancer. It is classified as cutaneous and non-cutaneous, with the former characterized by developing in sun-exposed areas of the skin, UV-light radiation being its most important risk factor and ordinarily affecting fair
Melanoma is the deadliest form of skin cancer. It is classified as cutaneous and non-cutaneous, with the former charact
Malignancy Risk and Recurrence with Psoriasis and its Treatments: A Concise Update.
Geller S, Xu H, Lebwohl M, Nardone B, Lacouture ME, Kheterpal M. Geller S, et al. Am J Clin Dermatol. 2018 Jun;19(3):363-375. doi: 10.1007/s40257-017-0337-2. Am J Clin Dermatol. 2018. PMID: 29260411 Free PMC article. Review.
Studies on methotrexate and cyclosporine, as well as older biological agents such as tumor necrosis factor inhibitors, have found no increased risk of non-cutaneous solid tumors; however, positive associations between cutaneous squamous cell carcinomas and certain t …
Studies on methotrexate and cyclosporine, as well as older biological agents such as tumor necrosis factor inhibitors, have found no increas …
Adjuvant systemic treatment for high-risk resected non-cutaneous melanomas: What is the evidence?
Tapia Rico G, Yong CH, Herrera Gómez RG. Tapia Rico G, et al. Crit Rev Oncol Hematol. 2021 Nov;167:103503. doi: 10.1016/j.critrevonc.2021.103503. Epub 2021 Oct 14. Crit Rev Oncol Hematol. 2021. PMID: 34656746 Review.
Non-cutaneous melanomas (mucosal, uveal, leptomeningeal, unknown primaries) represent around 5-10 % of all melanoma diagnoses. Non-cutaneous melanomas demonstrate differences in tumour biology, generally present with more advanced
Non-cutaneous melanomas (mucosal, uveal, leptomeningeal, unknown primaries) represent around 5-10 % of all melanoma
What hope for the future? GNAQ and uveal melanoma.
Sisley K, Doherty R, Cross NA. Sisley K, et al. Br J Ophthalmol. 2011 May;95(5):620-3. doi: 10.1136/bjo.2010.182097. Epub 2011 Mar 3. Br J Ophthalmol. 2011. PMID: 21378004 Review.
Uveal melanomas (UM) are aggressive ocular tumours that spread to the liver. ...Recently, mutations of guanine nucleotide-binding protein G(q) subunit alpha (GNAQ, or G-alpha-q), which effectively turn it into a dominantly acting oncogene, have been identified in approxima …
Uveal melanomas (UM) are aggressive ocular tumours that spread to the liver. ...Recently, mutations of guanine nucleotide-binding pro …
The risk of transmitting cutaneous malignancy through skin transplantation: a literature-based risk assessment.
Bosma S, Van Wijk MJ, Richters CD, Beele H. Bosma S, et al. Cell Tissue Bank. 2015 Dec;16(4):503-12. doi: 10.1007/s10561-015-9497-6. Epub 2015 Jan 29. Cell Tissue Bank. 2015. PMID: 25631853 Review.
Circumstantial evidence, available for organ transplantation, was used to develop the following policy proposal for skin transplantation and cutaneous tumours. Malignant melanoma is an absolute contraindication for the donation of skin and also of other tissues, whereas, n …
Circumstantial evidence, available for organ transplantation, was used to develop the following policy proposal for skin transplantation and …
Primary melanoma of submandibular gland: case report and literature review of a very rare entity.
Mir Mohammad Sadeghi H, Dastgir R, Bozorg Zadeh S, Mashhadiabbas F, Karimi A, Mohammadi Khah M. Mir Mohammad Sadeghi H, et al. BMC Oral Health. 2022 Aug 14;22(1):351. doi: 10.1186/s12903-022-02380-2. BMC Oral Health. 2022. PMID: 35965324 Free PMC article. Review.
BACKGROUND: Cutaneous melanomas account for more than 95% of all cases of primary melanoma, making non-cutaneous primary melanomas truly rare. Cases of primary mucosal melanomas of the oral cavity have been widely described; however, inst …
BACKGROUND: Cutaneous melanomas account for more than 95% of all cases of primary melanoma, making non-cutaneous
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