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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1967 1
1968 1
1970 1
1973 1
1976 3
1978 7
1979 1
1980 1
1981 6
1982 10
1983 5
1984 9
1985 11
1986 9
1987 5
1988 18
1989 14
1990 18
1991 13
1992 14
1993 26
1994 19
1995 19
1996 12
1997 14
1998 18
1999 25
2000 23
2001 18
2002 12
2003 25
2004 24
2005 20
2006 24
2007 20
2008 17
2009 20
2010 21
2011 30
2012 33
2013 26
2014 38
2015 37
2016 35
2017 32
2018 35
2019 37
2020 37
2021 38
2022 31
2023 39
2024 14

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887 results

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Page 1
Tinnitus.
Baguley D, McFerran D, Hall D. Baguley D, et al. Lancet. 2013 Nov 9;382(9904):1600-7. doi: 10.1016/S0140-6736(13)60142-7. Epub 2013 Jul 2. Lancet. 2013. PMID: 23827090 Free article. Review.
Tinnitus is a common medical symptom that can be debilitating. Risk factors include hearing loss, ototoxic medication, head injury, and depression. At presentation, the possibilities of otological disease, anxiety, and depression should be considered. ...
Tinnitus is a common medical symptom that can be debilitating. Risk factors include hearing loss, ototoxic medication, head injury, a …
Aminoglycoside- and Cisplatin-Induced Ototoxicity: Mechanisms and Otoprotective Strategies.
Kros CJ, Steyger PS. Kros CJ, et al. Cold Spring Harb Perspect Med. 2019 Nov 1;9(11):a033548. doi: 10.1101/cshperspect.a033548. Cold Spring Harb Perspect Med. 2019. PMID: 30559254 Free PMC article. Review.
Ototoxicity refers to damage of inner ear structures (i.e., the cochlea and vestibule) and their function (hearing and balance) following exposure to specific in-hospital medications (i.e., aminoglycoside antibiotics, platinum-based drugs), as well as a variety of environm …
Ototoxicity refers to damage of inner ear structures (i.e., the cochlea and vestibule) and their function (hearing and balance) follo …
Mechanisms of Ototoxicity and Otoprotection.
Steyger PS. Steyger PS. Otolaryngol Clin North Am. 2021 Dec;54(6):1101-1115. doi: 10.1016/j.otc.2021.08.007. Otolaryngol Clin North Am. 2021. PMID: 34774227 Free PMC article. Review.
This article reviews the fundamental mechanisms underlying ototoxicity by clinically relevant, hospital-prescribed medications (ie, aminoglycoside antibiotics or cisplatin, as illustrative examples). Also reviewed are current strategies to prevent prescribed medication-ind …
This article reviews the fundamental mechanisms underlying ototoxicity by clinically relevant, hospital-prescribed medications (ie, a …
Drug-Induced Ototoxicity: A Comprehensive Review and Reference Guide.
Rizk HG, Lee JA, Liu YF, Endriukaitis L, Isaac JL, Bullington WM. Rizk HG, et al. Pharmacotherapy. 2020 Dec;40(12):1265-1275. doi: 10.1002/phar.2478. Epub 2020 Nov 18. Pharmacotherapy. 2020. PMID: 33080070 Review.
OBJECTIVE: In an era of increasing polypharmacy, adverse drug effects such as ototoxicity have significant public health implications. Despite the availability of evidence, many health care professionals may not know the risk of ototoxicity in common medications. Th …
OBJECTIVE: In an era of increasing polypharmacy, adverse drug effects such as ototoxicity have significant public health implications …
Aminoglycoside-induced ototoxicity.
Selimoglu E. Selimoglu E. Curr Pharm Des. 2007;13(1):119-26. doi: 10.2174/138161207779313731. Curr Pharm Des. 2007. PMID: 17266591 Review.
Two mutations in the mitochondrial 12S ribosomal RNA gene have been previously reported to predispose carriers to aminoglycoside-induced ototoxicity. As aminoglycosides are indispensable agents both in the treatment of infections and Meniere's disease, a great effort has b …
Two mutations in the mitochondrial 12S ribosomal RNA gene have been previously reported to predispose carriers to aminoglycoside-induced …
[Management of chemotherapy side effects and their long-term sequelae].
Zraik IM, Heß-Busch Y. Zraik IM, et al. Urologe A. 2021 Jul;60(7):862-871. doi: 10.1007/s00120-021-01569-7. Epub 2021 Jun 29. Urologe A. 2021. PMID: 34185118 Review. German.
These include general side effects such as anemia, neutropenia, nausea, vomiting, diarrhea, mucositis or paravasation as well as special toxicities like ototoxicity, nephrotoxicity, pulmonary toxicity, neurotoxicity or Raynaud's syndrome. ...
These include general side effects such as anemia, neutropenia, nausea, vomiting, diarrhea, mucositis or paravasation as well as special tox …
Prevention of cisplatin-induced ototoxicity in children and adolescents with cancer: a clinical practice guideline.
Freyer DR, Brock PR, Chang KW, Dupuis LL, Epelman S, Knight K, Mills D, Phillips R, Potter E, Risby D, Simpkin P, Sullivan M, Cabral S, Robinson PD, Sung L. Freyer DR, et al. Lancet Child Adolesc Health. 2020 Feb;4(2):141-150. doi: 10.1016/S2352-4642(19)30336-0. Epub 2019 Dec 19. Lancet Child Adolesc Health. 2020. PMID: 31866182 Free PMC article. Review.
Despite ototoxicity being a prevalent consequence of cisplatin chemotherapy, little guidance exists on interventions to prevent this permanent and progressive adverse event. To develop a clinical practice guideline for the prevention of cisplatin-induced ototoxicity …
Despite ototoxicity being a prevalent consequence of cisplatin chemotherapy, little guidance exists on interventions to prevent this …
Cisplatin-induced ototoxicity: From signaling network to therapeutic targets.
Wang X, Zhou Y, Wang D, Wang Y, Zhou Z, Ma X, Liu X, Dong Y. Wang X, et al. Biomed Pharmacother. 2023 Jan;157:114045. doi: 10.1016/j.biopha.2022.114045. Epub 2022 Nov 28. Biomed Pharmacother. 2023. PMID: 36455457 Free article. Review.
Recent studies have also reported the role of inflammation in cisplatin-induced ototoxicity. In this article, we preform a narrative review of the latest reported molecular mechanisms of cisplatin-induced ototoxicity, from extracellular to intracellular. ...Consider …
Recent studies have also reported the role of inflammation in cisplatin-induced ototoxicity. In this article, we preform a narrative …
Mechanisms of Hair Cell Damage and Repair.
Wagner EL, Shin JB. Wagner EL, et al. Trends Neurosci. 2019 Jun;42(6):414-424. doi: 10.1016/j.tins.2019.03.006. Epub 2019 Apr 13. Trends Neurosci. 2019. PMID: 30992136 Free PMC article. Review.
The maintenance of hair cells is further challenged by damage from a variety of other ototoxic factors, including loud noise, aging, genetic defects, and ototoxic drugs. ...
The maintenance of hair cells is further challenged by damage from a variety of other ototoxic factors, including loud noise, aging, …
Aminoglycoside Vestibulotoxicity.
Rutka J. Rutka J. Adv Otorhinolaryngol. 2019;82:101-110. doi: 10.1159/000490277. Epub 2019 Jan 15. Adv Otorhinolaryngol. 2019. PMID: 30947191 Review.
Many pharmaceuticals have ototoxicity (both cochlear and/or vestibular) as part of their adverse medication profile. ...Commercially available ototopical aminoglycoside preparations for the treatment of external/middle ear disease in the presence of a tympanic membrane def …
Many pharmaceuticals have ototoxicity (both cochlear and/or vestibular) as part of their adverse medication profile. ...Commercially …
887 results