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1987
2025

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 1
1988 2
1989 1
1991 6
1992 1
1993 6
1994 3
1995 2
1996 3
1997 3
1998 5
1999 6
2000 15
2001 7
2002 2
2003 9
2004 4
2005 8
2006 8
2007 7
2008 5
2009 10
2010 13
2011 11
2012 19
2013 13
2014 12
2015 22
2016 21
2017 10
2018 25
2019 17
2020 26
2021 20
2022 8
2023 3
2024 13
2025 1

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306 results

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Page 1
PGC-1alpha: a key regulator of energy metabolism.
Liang H, Ward WF. Liang H, et al. Adv Physiol Educ. 2006 Dec;30(4):145-51. doi: 10.1152/advan.00052.2006. Adv Physiol Educ. 2006. PMID: 17108241 Free article. Review.
Peroxisome proliferator-activated receptor-gamma coactivator (PGC)-1alpha is a member of a family of transcription coactivators that plays a central role in the regulation of cellular energy metabolism. ...It is highly likely that PGC-1alpha is intimately involved in di
Peroxisome proliferator-activated receptor-gamma coactivator (PGC)-1alpha is a member of a family of transcription coactivators that
Peroxisome: Metabolic Functions and Biogenesis.
Okumoto K, Tamura S, Honsho M, Fujiki Y. Okumoto K, et al. Adv Exp Med Biol. 2020;1299:3-17. doi: 10.1007/978-3-030-60204-8_1. Adv Exp Med Biol. 2020. PMID: 33417203 Review.
Such metabolic functions and the exclusive importance of peroxisomes have been highlighted in fatal human genetic disease called peroxisomal biogenesis disorders (PBDs). Recent advances in this field have identified over 30 PEX genes encoding pe …
Such metabolic functions and the exclusive importance of peroxisomes have been highlighted in fatal human genetic disease call …
Sirt1 and the Mitochondria.
Tang BL. Tang BL. Mol Cells. 2016 Feb;39(2):87-95. doi: 10.14348/molcells.2016.2318. Epub 2016 Feb 2. Mol Cells. 2016. PMID: 26831453 Free PMC article. Review.
Although primarily a nuclear protein, Sirt1's deacetylation of Peroxisome proliferator-activated receptor Gamma Coactivator-1alpha (PGC-1alpha) has been extensively implicated in metabolic control and mitochondrial biogenesis, which was proposed to partially underli …
Although primarily a nuclear protein, Sirt1's deacetylation of Peroxisome proliferator-activated receptor Gamma Coactivator-1alpha (P …
Mitochondrial energetics in the kidney.
Bhargava P, Schnellmann RG. Bhargava P, et al. Nat Rev Nephrol. 2017 Oct;13(10):629-646. doi: 10.1038/nrneph.2017.107. Epub 2017 Aug 14. Nat Rev Nephrol. 2017. PMID: 28804120 Free PMC article. Review.
Mitochondria provide the energy to drive these important functions and can adapt to different metabolic conditions through a number of signalling pathways (for example, mechanistic target of rapamycin (mTOR) and AMP-activated protein kinase (AMPK) pathways) that activate the tran …
Mitochondria provide the energy to drive these important functions and can adapt to different metabolic conditions through a number of signa …
The physiological functions of human peroxisomes.
Wanders RJA, Baes M, Ribeiro D, Ferdinandusse S, Waterham HR. Wanders RJA, et al. Physiol Rev. 2023 Jan 1;103(1):957-1024. doi: 10.1152/physrev.00051.2021. Epub 2022 Aug 11. Physiol Rev. 2023. PMID: 35951481 Free article. Review.
Among others these include the Zellweger spectrum disorders, X-linked adrenoleukodystrophy, and Refsum disease. To fulfill their role in metabolism, peroxisomes require continued interaction with other subcellular organelles including lipid droplets, lysosome …
Among others these include the Zellweger spectrum disorders, X-linked adrenoleukodystrophy, and Refsum disease. To fulfill the …
The menage a trois of autophagy, lipid droplets and liver disease.
Filali-Mouncef Y, Hunter C, Roccio F, Zagkou S, Dupont N, Primard C, Proikas-Cezanne T, Reggiori F. Filali-Mouncef Y, et al. Autophagy. 2022 Jan;18(1):50-72. doi: 10.1080/15548627.2021.1895658. Epub 2021 Apr 2. Autophagy. 2022. PMID: 33794741 Free PMC article. Review.
Here we provide an overview on our current knowledge of the biogenesis and functions of LDs, and the mechanisms underlying their lysosomal turnover by autophagic processes. ...Particular attention is paid to the role of macroautophagy and macrolipophagy in relation to the …
Here we provide an overview on our current knowledge of the biogenesis and functions of LDs, and the mechanisms underlying their lyso …
Mitochondrial biogenesis in neurodegeneration.
Li PA, Hou X, Hao S. Li PA, et al. J Neurosci Res. 2017 Oct;95(10):2025-2029. doi: 10.1002/jnr.24042. Epub 2017 Mar 16. J Neurosci Res. 2017. PMID: 28301064 Review.
Therefore, preserving or promoting mitochondrial function is a potential therapeutic target for the treatment of neurodegenerative disorders. Mitochondrial biogenesis is a process by which new mitochondria are produced from existing mitochondria. This biogenesis
Therefore, preserving or promoting mitochondrial function is a potential therapeutic target for the treatment of neurodegenerative disord
Molecular Mechanisms of Muscle Fatigue.
Constantin-Teodosiu D, Constantin D. Constantin-Teodosiu D, et al. Int J Mol Sci. 2021 Oct 27;22(21):11587. doi: 10.3390/ijms222111587. Int J Mol Sci. 2021. PMID: 34769017 Free PMC article. Review.
The leading cause underpinning the development of chronic fatigue is related to muscle wasting mediated by aging, immobilization, insulin resistance (through high-fat dietary intake or pharmacologically mediated Peroxisome Proliferator-Activated Receptor (PPAR) agonism), d …
The leading cause underpinning the development of chronic fatigue is related to muscle wasting mediated by aging, immobilization, insulin re …
The CD36-PPARgamma Pathway in Metabolic Disorders.
Maréchal L, Laviolette M, Rodrigue-Way A, Sow B, Brochu M, Caron V, Tremblay A. Maréchal L, et al. Int J Mol Sci. 2018 May 21;19(5):1529. doi: 10.3390/ijms19051529. Int J Mol Sci. 2018. PMID: 29883404 Free PMC article. Review.
Uncovering the biological role of nuclear receptor peroxisome proliferator-activated receptors (PPARs) has greatly advanced our knowledge of the transcriptional control of glucose and energy metabolism. ...The identification of the GHRP-CD36-PPARgamma pathway in controllin …
Uncovering the biological role of nuclear receptor peroxisome proliferator-activated receptors (PPARs) has greatly advanced our knowl …
The peroxisome: an update on mysteries 3.0.
Kumar R, Islinger M, Worthy H, Carmichael R, Schrader M. Kumar R, et al. Histochem Cell Biol. 2024 Feb;161(2):99-132. doi: 10.1007/s00418-023-02259-5. Epub 2024 Jan 20. Histochem Cell Biol. 2024. PMID: 38244103 Free PMC article. Review.
Loss of peroxisomal functions causes severe metabolic disorders in humans. Furthermore, peroxisomes also fulfil protective roles in pathogen and viral defence and immunity, highlighting their wider significance in human health and disease. ...Furthermo …
Loss of peroxisomal functions causes severe metabolic disorders in humans. Furthermore, peroxisomes also fulfil protect …
306 results