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Page 1
DICER1 and Associated Conditions: Identification of At-risk Individuals and Recommended Surveillance Strategies.
Schultz KAP, Williams GM, Kamihara J, Stewart DR, Harris AK, Bauer AJ, Turner J, Shah R, Schneider K, Schneider KW, Carr AG, Harney LA, Baldinger S, Frazier AL, Orbach D, Schneider DT, Malkin D, Dehner LP, Messinger YH, Hill DA. Schultz KAP, et al. Clin Cancer Res. 2018 May 15;24(10):2251-2261. doi: 10.1158/1078-0432.CCR-17-3089. Epub 2018 Jan 17. Clin Cancer Res. 2018. PMID: 29343557 Free PMC article. Review.
In addition to conferring increased cancer risks for pleuropulmonary blastoma (PPB) and ovarian sex cord-stromal tumors, particularly Sertoli-Leydig cell tumor, individuals with pathogenic germline DICER1 variants may also develop lung cysts, cystic nephroma, renal …
In addition to conferring increased cancer risks for pleuropulmonary blastoma (PPB) and ovarian sex cord-stromal tumors, parti …
Congenital Pulmonary Airway Malformations With a Reconsideration and Current Perspective on the Stocker Classification.
Dehner LP, Schultz KAP, Hill DA. Dehner LP, et al. Pediatr Dev Pathol. 2023 May-Jun;26(3):241-249. doi: 10.1177/10935266221146823. Epub 2023 Feb 21. Pediatr Dev Pathol. 2023. PMID: 37334833 Review.
This review highlights mutational events either at the somatic level in KRAS (CPAM types 1 and possibly 3) or germline variants in congenital acinar dysplasia, formerly CPAM type 0, and pleuropulmonary blastoma (PPB), type I, formerly CPAM type 4. The potential for …
This review highlights mutational events either at the somatic level in KRAS (CPAM types 1 and possibly 3) or germline variants in congenita …
Congenital pulmonary airway malformations: state-of-the-art review for pediatrician's use.
Leblanc C, Baron M, Desselas E, Phan MH, Rybak A, Thouvenin G, Lauby C, Irtan S. Leblanc C, et al. Eur J Pediatr. 2017 Dec;176(12):1559-1571. doi: 10.1007/s00431-017-3032-7. Epub 2017 Oct 19. Eur J Pediatr. 2017. PMID: 29046943 Review.
New molecular or pathological pathways may help in the distinction of type 4 CPAM from type I pleuropulmonary blastoma....
New molecular or pathological pathways may help in the distinction of type 4 CPAM from type I pleuropulmonary blastoma....
DICER1 tumor predisposition syndrome: an evolving story initiated with the pleuropulmonary blastoma.
González IA, Stewart DR, Schultz KAP, Field AP, Hill DA, Dehner LP. González IA, et al. Mod Pathol. 2022 Jan;35(1):4-22. doi: 10.1038/s41379-021-00905-8. Epub 2021 Oct 1. Mod Pathol. 2022. PMID: 34599283 Free PMC article. Review.
The most common tumor seen clinically is the pleuropulmonary blastoma (PPB), a lung neoplasm of early childhood which is classified on its morphologic features into four types (IR, I, II and III) with tumor progression over time within the first 4-5 years of life fr …
The most common tumor seen clinically is the pleuropulmonary blastoma (PPB), a lung neoplasm of early childhood which is class …
Type I pleuropulmonary blastoma: pathology and biology study of 51 cases from the international pleuropulmonary blastoma registry.
Hill DA, Jarzembowski JA, Priest JR, Williams G, Schoettler P, Dehner LP. Hill DA, et al. Am J Surg Pathol. 2008 Feb;32(2):282-95. doi: 10.1097/PAS.0b013e3181484165. Am J Surg Pathol. 2008. PMID: 18223332 Review.
Pleuropulmonary blastoma (PPB) is a malignant neoplasm of the lung that presents in early childhood. ...
Pleuropulmonary blastoma (PPB) is a malignant neoplasm of the lung that presents in early childhood. ...
Congenital lung lesions.
Puligandla PS, Laberge JM. Puligandla PS, et al. Clin Perinatol. 2012 Jun;39(2):331-47. doi: 10.1016/j.clp.2012.04.009. Clin Perinatol. 2012. PMID: 22682383 Review.
This review examines the current status of fetal diagnosis and treatment of these lesions; reviews the various classifications, including congenital cystic adenomatoid malformation/congenital pulmonary airway malformation, sequestrations, variants and hybrid lesions; discusses th …
This review examines the current status of fetal diagnosis and treatment of these lesions; reviews the various classifications, including co …
Cytomorphologic and immunocytochemical characterization of pediatric pleuropulmonary blastoma with a comprehensive review of the literature.
Gupta P, Chugh S, Gupta N, Gupta K, Sodhi KS, Kakkar N, Srinivasan R, Rohilla M, Kundu R, Trehan A, Bansal D, Peters NJ. Gupta P, et al. Diagn Cytopathol. 2024 Feb;52(2):103-115. doi: 10.1002/dc.25254. Epub 2023 Nov 14. Diagn Cytopathol. 2024. PMID: 37964698 Review.
INTRODUCTION: Pleuropulmonary blastoma (PPB) is a rare, aggressive, primary intrathoracic malignancy typically seen in infancy and early childhood. ...
INTRODUCTION: Pleuropulmonary blastoma (PPB) is a rare, aggressive, primary intrathoracic malignancy typically seen in infancy …
Multimodality Imaging of Pleuropulmonary Blastoma: Pearls, Pitfalls, and Differential Diagnosis.
Leung SS, Donuru A, Kandula V, Parekh MR, Saul D. Leung SS, et al. Semin Ultrasound CT MR. 2022 Feb;43(1):61-72. doi: 10.1053/j.sult.2021.05.007. Epub 2021 May 15. Semin Ultrasound CT MR. 2022. PMID: 35164911 Review.
Pleuropulmonary blastomas are classified as cystic (type I), mixed cystic and solid (type II), and solid (type III). Pleuropulmonary blastoma occurs in the same age group (0-6 years) as other more common solid tumors such as neuroblastoma and Wilms tumor. ...Surviva …
Pleuropulmonary blastomas are classified as cystic (type I), mixed cystic and solid (type II), and solid (type III). Pleuropulmonary
Imaging of DICER1 syndrome.
Guillerman RP, Foulkes WD, Priest JR. Guillerman RP, et al. Pediatr Radiol. 2019 Oct;49(11):1488-1505. doi: 10.1007/s00247-019-04429-x. Epub 2019 Oct 16. Pediatr Radiol. 2019. PMID: 31620849 Review.
The hallmarks of DICER1 syndrome are certain rare tumors including pleuropulmonary blastoma; cystic nephroma; ovarian Sertoli-Leydig cell tumor; sarcomas of the cervix, kidneys and cerebrum; pituitary blastoma; ciliary body medulloepithelioma; and nasal chondromesen …
The hallmarks of DICER1 syndrome are certain rare tumors including pleuropulmonary blastoma; cystic nephroma; ovarian Sertoli- …
61 results