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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 1
1968 1
1969 2
1970 1
1971 2
1972 4
1973 2
1974 4
1975 10
1976 5
1977 8
1978 9
1979 8
1980 12
1981 12
1982 18
1983 18
1984 28
1985 25
1986 19
1987 21
1988 41
1989 54
1990 77
1991 72
1992 74
1993 79
1994 107
1995 105
1996 102
1997 116
1998 143
1999 173
2000 203
2001 231
2002 285
2003 283
2004 310
2005 337
2006 396
2007 380
2008 425
2009 377
2010 402
2011 440
2012 462
2013 479
2014 525
2015 460
2016 541
2017 543
2018 489
2019 470
2020 534
2021 566
2022 439
2023 414
2024 111

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10,449 results

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Page 1
Non-IgE-Mediated Gastrointestinal Food Allergies in Children: An Update.
Labrosse R, Graham F, Caubet JC. Labrosse R, et al. Nutrients. 2020 Jul 14;12(7):2086. doi: 10.3390/nu12072086. Nutrients. 2020. PMID: 32674427 Free PMC article. Review.
Non-immunoglobulin E-mediated gastrointestinal food allergic disorders (non-IgE-GI-FA) include food protein-induced enterocolitis syndrome (FPIES), food protein-induced enteropathy (FPE) and food protein-induced allergic proctocolitis (FPIAP), which present w …
Non-immunoglobulin E-mediated gastrointestinal food allergic disorders (non-IgE-GI-FA) include food protein-induced enterocolitis syn …
Molecular chaperones in protein folding and proteostasis.
Hartl FU, Bracher A, Hayer-Hartl M. Hartl FU, et al. Nature. 2011 Jul 20;475(7356):324-32. doi: 10.1038/nature10317. Nature. 2011. PMID: 21776078 Review.
Most proteins must fold into defined three-dimensional structures to gain functional activity. ...Because protein molecules are highly dynamic, constant chaperone surveillance is required to ensure protein homeostasis (proteostasis). ...
Most proteins must fold into defined three-dimensional structures to gain functional activity. ...Because protein molecules ar …
Current strategies in extending half-lives of therapeutic proteins.
Zaman R, Islam RA, Ibnat N, Othman I, Zaini A, Lee CY, Chowdhury EH. Zaman R, et al. J Control Release. 2019 May 10;301:176-189. doi: 10.1016/j.jconrel.2019.02.016. Epub 2019 Mar 5. J Control Release. 2019. PMID: 30849445 Review.
Size and hydrophobicity of protein molecules make them prone to kidney filtration and liver metabolism. On the other hand, proteasomes responsible for protein destruction possess the capability of specifically recognizing almost all kinds of foreign proteins …
Size and hydrophobicity of protein molecules make them prone to kidney filtration and liver metabolism. On the other hand, proteasome …
Laboratory Diagnostics in Thrombophilia.
Linnemann B, Hart C. Linnemann B, et al. Hamostaseologie. 2019 Feb;39(1):49-61. doi: 10.1055/s-0039-1677840. Epub 2019 Jan 31. Hamostaseologie. 2019. PMID: 30703819 Review.
Immunologic antigen assays and chromogenic or clot-based activity assays are used to identify deficiencies in the natural coagulation inhibitors antithrombin, protein C and protein S. Because pre-analytical errors and acquired causes of low antithrombin, p …
Immunologic antigen assays and chromogenic or clot-based activity assays are used to identify deficiencies in the natural coagulation inhibi …
BET proteins: Biological functions and therapeutic interventions.
Guo J, Zheng Q, Peng Y. Guo J, et al. Pharmacol Ther. 2023 Mar;243:108354. doi: 10.1016/j.pharmthera.2023.108354. Epub 2023 Feb 3. Pharmacol Ther. 2023. PMID: 36739915 Review.
Bromodomain and extra-terminal (BET) family member proteins (BRD2, BRD3, BRD4 and BRDT) play a pivotal role in interpreting the epigenetic information of histone Kac modification, thus controlling gene expression, remodeling chromatin structures and avoid replicativ …
Bromodomain and extra-terminal (BET) family member proteins (BRD2, BRD3, BRD4 and BRDT) play a pivotal role in interpreting the epige …
Phage and Yeast Display.
Sheehan J, Marasco WA. Sheehan J, et al. Microbiol Spectr. 2015 Feb;3(1):AID-0028-2014. doi: 10.1128/microbiolspec.AID-0028-2014. Microbiol Spectr. 2015. PMID: 26104550 Free article. Review.
This specificity prevents negative impacts on the patient microbiome and avoids driving the resistance of nontarget species. The in vitro selection of human antibody fragment libraries displayed on phage or yeast surfaces represents a group of well-established technologies …
This specificity prevents negative impacts on the patient microbiome and avoids driving the resistance of nontarget species. The in v …
Avoiding Complications on the Upper Face Treatment With Botulinum Toxin: A Practical Guide.
Borba A, Matayoshi S, Rodrigues M. Borba A, et al. Aesthetic Plast Surg. 2022 Feb;46(1):385-394. doi: 10.1007/s00266-021-02483-1. Epub 2021 Aug 2. Aesthetic Plast Surg. 2022. PMID: 34341857 Free PMC article. Review.
Thus, this review aims to describe the main complications of treatment with BoNT on the upper face and to present a practical guide based on current evidence on how to avoid them. METHODS: The literature research considered published journal articles (clinical trials or sc …
Thus, this review aims to describe the main complications of treatment with BoNT on the upper face and to present a practical guide based on …
Advances in Treatment of Frontotemporal Dementia.
Magrath Guimet N, Zapata-Restrepo LM, Miller BL. Magrath Guimet N, et al. J Neuropsychiatry Clin Neurosci. 2022 Fall;34(4):316-327. doi: 10.1176/appi.neuropsych.21060166. Epub 2022 May 17. J Neuropsychiatry Clin Neurosci. 2022. PMID: 35578801 Review.
The clinical features of FTD are unique, with disinhibition, apathy, loss of empathy, and compulsions common. Motor changes occur later in the illness. The two major proteins that aggregate in the brain with FTD are tau and TDP-43, whereas a minority of patients aggregate …
The clinical features of FTD are unique, with disinhibition, apathy, loss of empathy, and compulsions common. Motor changes occur later in t …
Plasmid copy number and plasmid stability.
Friehs K. Friehs K. Adv Biochem Eng Biotechnol. 2004;86:47-82. doi: 10.1007/b12440. Adv Biochem Eng Biotechnol. 2004. PMID: 15088763 Review.
Many expression systems in research and industry use plasmids as vectors for the production of recombinant proteins or non-proteinous recombinant substances. Plasmids have an essential impact on productivity. ...Different methods for lab scale and industrial scale h …
Many expression systems in research and industry use plasmids as vectors for the production of recombinant proteins or non-protein …
The impact of PEGylation on biological therapies.
Veronese FM, Mero A. Veronese FM, et al. BioDrugs. 2008;22(5):315-29. doi: 10.2165/00063030-200822050-00004. BioDrugs. 2008. PMID: 18778113 Review.
In order to benefit from these favorable pharmacokinetic consequences, a variety of therapeutic proteins, peptides, and antibody fragments, as well as small molecule drugs, have been PEGylated. ...Releasable PEGs have been designed to slowly release the native protein …
In order to benefit from these favorable pharmacokinetic consequences, a variety of therapeutic proteins, peptides, and antibody frag …
10,449 results
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