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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 2
1964 2
1965 1
1966 2
1967 2
1968 10
1969 4
1970 4
1971 5
1972 3
1973 12
1974 11
1975 17
1976 3
1977 10
1978 8
1979 5
1980 9
1981 3
1982 10
1983 13
1984 13
1985 14
1986 14
1987 26
1988 15
1989 22
1990 24
1991 34
1992 46
1993 33
1994 40
1995 27
1996 20
1997 34
1998 33
1999 37
2000 48
2001 45
2002 56
2003 47
2004 37
2005 52
2006 74
2007 58
2008 61
2009 49
2010 75
2011 65
2012 70
2013 67
2014 66
2015 75
2016 72
2017 53
2018 44
2019 63
2020 68
2021 71
2022 69
2023 63
2024 31

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1,889 results

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Page 1
History of Puberty: Normal and Precocious.
Fuqua JS, Eugster EA. Fuqua JS, et al. Horm Res Paediatr. 2022;95(6):568-578. doi: 10.1159/000526464. Epub 2022 Nov 29. Horm Res Paediatr. 2022. PMID: 36446322 Free article. Review.
Spanning from bench to bedside, the history of normal and precocious puberty is characterized by a series of remarkable advances that have illuminated reproductive physiology and profoundly impacted clinical care. ...Development of long-acting analogs of GnRH revolutionize …
Spanning from bench to bedside, the history of normal and precocious puberty is characterized by a series of remarkable advances that …
Puberty: Onset and Progression.
Khan L. Khan L. Pediatr Ann. 2019 Apr 1;48(4):e141-e145. doi: 10.3928/19382359-20190322-01. Pediatr Ann. 2019. PMID: 30986314 Review.
The normal process of puberty is complex and involves many different hormonal pathways. A clear understanding of these pathways will help providers counsel patients on what to expect as they anticipate and progress through puberty as well as be alerted when puber …
The normal process of puberty is complex and involves many different hormonal pathways. A clear understanding of these pathways will …
Precocious puberty.
Gangat M, Radovick S. Gangat M, et al. Minerva Pediatr. 2020 Dec;72(6):491-500. doi: 10.23736/S0026-4946.20.05970-8. Epub 2020 Aug 4. Minerva Pediatr. 2020. PMID: 32748611 Review.
Precocious puberty (PP) is a common reason for referral to pediatric endocrinology clinics, with a strong female predominance. PP is a broad term encompassing benign variants of normal development, gonadotropin-dependent precious puberty (GDPP), and gonadotropin-ind …
Precocious puberty (PP) is a common reason for referral to pediatric endocrinology clinics, with a strong female predominance. PP is …
Disorders of Puberty: An Approach to Diagnosis and Management.
Klein DA, Emerick JE, Sylvester JE, Vogt KS. Klein DA, et al. Am Fam Physician. 2017 Nov 1;96(9):590-599. Am Fam Physician. 2017. PMID: 29094880 Free article. Review.
Disorders of puberty can profoundly impact physical and psychosocial well-being. ...Constitutional delay of growth and puberty is a common cause of delayed puberty; however, functional or persistent hypogonadism should be excluded. ...
Disorders of puberty can profoundly impact physical and psychosocial well-being. ...Constitutional delay of growth and pube …
Disorders of puberty.
Sultan C, Gaspari L, Maimoun L, Kalfa N, Paris F. Sultan C, et al. Best Pract Res Clin Obstet Gynaecol. 2018 Apr;48:62-89. doi: 10.1016/j.bpobgyn.2017.11.004. Epub 2017 Nov 14. Best Pract Res Clin Obstet Gynaecol. 2018. PMID: 29422239 Free article. Review.
Over the past 20 years, a clear secular trend toward the earlier onset of puberty has been described. A better knowledge should help clinicians attempting to define both precocious and delayed puberty (PP and DP, respectively). ...Estrogen therapy should be discusse …
Over the past 20 years, a clear secular trend toward the earlier onset of puberty has been described. A better knowledge should help …
Genetic and Epigenetic Control of Puberty.
Manotas MC, González DM, Céspedes C, Forero C, Rojas Moreno AP. Manotas MC, et al. Sex Dev. 2022;16(1):1-10. doi: 10.1159/000519039. Epub 2021 Oct 14. Sex Dev. 2022. PMID: 34649256 Free PMC article. Review.
There is a very wide variation in the age range of the onset of puberty, which follows a familial, ethnic, and sex pattern. The hypothalamic-pituitary-gonadal axis and several genetic, environmental, and nutritional factors play an important role in the onset of and …
There is a very wide variation in the age range of the onset of puberty, which follows a familial, ethnic, and sex pattern. The hypot …
Delayed Puberty.
Mohanraj S, Prasad HK. Mohanraj S, et al. Indian J Pediatr. 2023 Jun;90(6):590-597. doi: 10.1007/s12098-023-04577-x. Epub 2023 May 2. Indian J Pediatr. 2023. PMID: 37127825 Review.
Testicular volume 4 ml and appearance of breast budding are the first signs of puberty. Delayed puberty is diagnosed in the absence of thelarche by 13 y or menarche by 15 y in girls and absence of testicular enlargement by 14 y in boys. ...Attainment of adult sexual …
Testicular volume 4 ml and appearance of breast budding are the first signs of puberty. Delayed puberty is diagnosed in the ab …
Pubertal development and regulation.
Abreu AP, Kaiser UB. Abreu AP, et al. Lancet Diabetes Endocrinol. 2016 Mar;4(3):254-264. doi: 10.1016/S2213-8587(15)00418-0. Epub 2016 Feb 4. Lancet Diabetes Endocrinol. 2016. PMID: 26852256 Free PMC article. Review.
The hypothalamic-pituitary-gonadal axis controls puberty and reproduction and is tightly regulated by a complex network of excitatory and inhibitory factors. ...The age of puberty onset varies between individuals and the timing of puberty initiation is …
The hypothalamic-pituitary-gonadal axis controls puberty and reproduction and is tightly regulated by a complex network of exc …
Normal and Premature Adrenarche.
Rosenfield RL. Rosenfield RL. Endocr Rev. 2021 Nov 16;42(6):783-814. doi: 10.1210/endrev/bnab009. Endocr Rev. 2021. PMID: 33788946 Free PMC article. Review.
Serum DHEAS and testosterone levels increase to levels normal for early female puberty. It is associated with mildly increased risks for obesity, insulin resistance, and possibly mood disorder and polycystic ovary syndrome. Between 5% and 10% of PP is due to virilizing …
Serum DHEAS and testosterone levels increase to levels normal for early female puberty. It is associated with mildly increased risks …
A review of the genetics and epigenetics of central precocious puberty.
Moise-Silverman J, Silverman LA. Moise-Silverman J, et al. Front Endocrinol (Lausanne). 2022 Dec 2;13:1029137. doi: 10.3389/fendo.2022.1029137. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36531492 Free PMC article. Review.
Gonadotrophin dependent sexual precocity, commonly referred to as central precocious puberty (CPP), results from a premature reactivation of the hypothalamic-pituitary-gonadal (HPG) axis before the normal age of pubertal onset. CPP is historically described as girls …
Gonadotrophin dependent sexual precocity, commonly referred to as central precocious puberty (CPP), results from a premature reactiva …
1,889 results