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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 1
1964 1
1967 1
1970 1
1972 1
1974 3
1975 2
1976 2
1978 2
1979 1
1980 1
1981 1
1983 3
1984 3
1985 3
1986 2
1987 2
1988 16
1989 8
1990 9
1991 5
1992 6
1993 10
1994 22
1995 19
1996 20
1997 10
1998 19
1999 7
2000 14
2001 17
2002 13
2003 18
2004 22
2005 20
2006 22
2007 21
2008 36
2009 20
2010 30
2011 20
2012 38
2013 36
2014 46
2015 49
2016 25
2017 41
2018 31
2019 22
2020 31
2021 42
2022 41
2023 31
2024 7

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805 results

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Page 1
Management of Perianal Crohn's Disease.
Parian AM, Obi M, Fleshner P, Schwartz DA. Parian AM, et al. Am J Gastroenterol. 2023 Aug 1;118(8):1323-1331. doi: 10.14309/ajg.0000000000002326. Epub 2023 Jun 19. Am J Gastroenterol. 2023. PMID: 37207318 Review.
A multidisciplinary approach is necessary for the successful management of Crohn's disease with perianal fistula. Medical management is required to treat the underlying immune dysregulation to heal the luminal inflammation and the inflammation within the fistula tra …
A multidisciplinary approach is necessary for the successful management of Crohn's disease with perianal fistula. Medical management …
Perianal Abscesses and Fistulas in Infants and Children.
Gosemann JH, Lacher M. Gosemann JH, et al. Eur J Pediatr Surg. 2020 Oct;30(5):386-390. doi: 10.1055/s-0040-1716726. Epub 2020 Sep 28. Eur J Pediatr Surg. 2020. PMID: 32987435 Review.
Perianal abscess (PA) and fistula-in-ano (FIA) are common entities in infancy. Although several hypotheses have been suggested, the pathogenesis of PA/FIA remains elusive. ...
Perianal abscess (PA) and fistula-in-ano (FIA) are common entities in infancy. Although several hypotheses have been suggested, the p …
Modern management of anal fistula.
Limura E, Giordano P. Limura E, et al. World J Gastroenterol. 2015 Jan 7;21(1):12-20. doi: 10.3748/wjg.v21.i1.12. World J Gastroenterol. 2015. PMID: 25574077 Free PMC article. Review.
Ideal surgical treatment for anal fistula should aim to eradicate sepsis and promote healing of the tract, whilst preserving the sphincters and the mechanism of continence. ...Among them, the ligation of intersphincteric fistula tract procedure appears to be safe an …
Ideal surgical treatment for anal fistula should aim to eradicate sepsis and promote healing of the tract, whilst preserving the sphi …
Perianal abscess.
Sahnan K, Adegbola SO, Tozer PJ, Watfah J, Phillips RK. Sahnan K, et al. BMJ. 2017 Feb 21;356:j475. doi: 10.1136/bmj.j475. BMJ. 2017. PMID: 28223268 Free article. Review. No abstract available.
Perianal fistulizing Crohn's disease: pathogenesis, diagnosis and therapy.
Panés J, Rimola J. Panés J, et al. Nat Rev Gastroenterol Hepatol. 2017 Nov;14(11):652-664. doi: 10.1038/nrgastro.2017.104. Epub 2017 Aug 9. Nat Rev Gastroenterol Hepatol. 2017. PMID: 28790453 Review.
Factors involved in the pathogenesis of perianal fistulizing Crohn's disease include an increased production of transforming growth factor beta, TNF and IL-13 in the inflammatory infiltrate that induce epithelial-to-mesenchymal transition and upregulation of matrix metalloprotein …
Factors involved in the pathogenesis of perianal fistulizing Crohn's disease include an increased production of transforming growth factor b …
Risk Factors for Recurrence after anal fistula surgery: A meta-analysis.
Mei Z, Wang Q, Zhang Y, Liu P, Ge M, Du P, Yang W, He Y. Mei Z, et al. Int J Surg. 2019 Sep;69:153-164. doi: 10.1016/j.ijsu.2019.08.003. Epub 2019 Aug 7. Int J Surg. 2019. PMID: 31400504 Free article. Review.
We performed a meta-analysis to summarize and assess the credibility of evidence of potential risk factors for anal fistula recurrence (AFR) after surgery. METHODS: Pubmed and EMBASE without language restriction were searched from inception to April 2018 that reported risk …
We performed a meta-analysis to summarize and assess the credibility of evidence of potential risk factors for anal fistula recurrenc …
AGA Technical Review on the Medical Management of Moderate to Severe Luminal and Perianal Fistulizing Crohn's Disease.
Singh S, Proctor D, Scott FI, Falck-Ytter Y, Feuerstein JD. Singh S, et al. Gastroenterology. 2021 Jun;160(7):2512-2556.e9. doi: 10.1053/j.gastro.2021.04.023. Gastroenterology. 2021. PMID: 34051985 Free PMC article. Review.
Finally, in adult outpatients with moderate to severe fistulizing CD, this review addressed the efficacy of pharmacologic interventions for achieving fistula and the role of adjunctive antibiotics without clear evidence of active infection....
Finally, in adult outpatients with moderate to severe fistulizing CD, this review addressed the efficacy of pharmacologic interventions for …
Approach to medical therapy in perianal Crohn's disease.
Vasudevan A, Bruining DH, Loftus EV Jr, Faubion W, Ehman EC, Raffals L. Vasudevan A, et al. World J Gastroenterol. 2021 Jul 7;27(25):3693-3704. doi: 10.3748/wjg.v27.i25.3693. World J Gastroenterol. 2021. PMID: 34321838 Free PMC article. Review.
Anti-tumor necrosis factor (anti-TNF) therapy, including infliximab and adalimumab, remain preferred medical therapies for perianal Crohn's disease. Infliximab has been shown to be efficacious in improving fistula closure rates in randomized controlled trials. Clinicians c …
Anti-tumor necrosis factor (anti-TNF) therapy, including infliximab and adalimumab, remain preferred medical therapies for perianal Crohn's …
Classifying perianal fistulising Crohn's disease: an expert consensus to guide decision-making in daily practice and clinical trials.
Geldof J, Iqbal N, LeBlanc JF, Anandabaskaran S, Sawyer R, Buskens C, Bemelman W, Gecse K, Lundby L, Lightner AL, Danese S, Spinelli A, Carvello M, Faiz O, Warusavitarne J, Lung P, De Looze D, D'Hoore A, Vermeire S, Hart A, Tozer P. Geldof J, et al. Lancet Gastroenterol Hepatol. 2022 Jun;7(6):576-584. doi: 10.1016/S2468-1253(22)00007-3. Epub 2022 Mar 21. Lancet Gastroenterol Hepatol. 2022. PMID: 35325623 Review.
Key elements include stratification according to disease severity as well as disease outcome; synchronisation of patient and clinician goals in decision making, with a proactive, combined medical and surgical approach, on a treat to patient goal basis; and identification of indic …
Key elements include stratification according to disease severity as well as disease outcome; synchronisation of patient and clinician goals …
805 results