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2025

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Year Number of Results
1978 1
1979 1
1983 2
1987 1
1988 3
1989 1
1990 5
1991 3
1992 3
1993 3
1995 3
1996 2
1997 1
1998 6
1999 9
2000 3
2001 8
2002 3
2003 8
2004 2
2005 2
2006 11
2007 14
2008 4
2009 14
2010 14
2011 9
2012 10
2013 11
2014 23
2015 12
2016 22
2017 14
2018 28
2019 10
2020 21
2021 16
2022 22
2023 16
2024 21
2025 2

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322 results

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Page 1
Age-related macular degeneration.
Fleckenstein M, Keenan TDL, Guymer RH, Chakravarthy U, Schmitz-Valckenberg S, Klaver CC, Wong WT, Chew EY. Fleckenstein M, et al. Nat Rev Dis Primers. 2021 May 6;7(1):31. doi: 10.1038/s41572-021-00265-2. Nat Rev Dis Primers. 2021. PMID: 33958600 Review.
AMD is characterized by accumulation of extracellular deposits, namely drusen, along with progressive degeneration of photoreceptors and adjacent tissues. AMD is a multifactorial disease encompassing a complex interplay between ageing, environmental risk factors and geneti …
AMD is characterized by accumulation of extracellular deposits, namely drusen, along with progressive degeneration of photoreceptors …
Age-related macular degeneration.
Mitchell P, Liew G, Gopinath B, Wong TY. Mitchell P, et al. Lancet. 2018 Sep 29;392(10153):1147-1159. doi: 10.1016/S0140-6736(18)31550-2. Lancet. 2018. PMID: 30303083 Review.
Clinically, it is classified as early-stage (medium-sized drusen and retinal pigmentary changes) to late-stage (neovascular and atrophic). Age-related macular degeneration is a multifactorial disorder, with dysregulation in the complement, lipid, angiogenic, inflamm …
Clinically, it is classified as early-stage (medium-sized drusen and retinal pigmentary changes) to late-stage (neovascular an …
Autophagy in age-related macular degeneration.
Kaarniranta K, Blasiak J, Liton P, Boulton M, Klionsky DJ, Sinha D. Kaarniranta K, et al. Autophagy. 2023 Feb;19(2):388-400. doi: 10.1080/15548627.2022.2069437. Epub 2022 May 1. Autophagy. 2023. PMID: 35468037 Free PMC article. Review.
The progression of AMD is initially characterized by atrophic alterations in the retinal pigment epithelium, as well as the formation of lysosomal lipofuscin and extracellular drusen deposits. ...This review describes selective and secretory autophagy and their role …
The progression of AMD is initially characterized by atrophic alterations in the retinal pigment epithelium, as well as the formation …
Potential Therapeutic Candidates for Age-Related Macular Degeneration (AMD).
Nashine S. Nashine S. Cells. 2021 Sep 19;10(9):2483. doi: 10.3390/cells10092483. Cells. 2021. PMID: 34572131 Free PMC article. Review.
Aging contributes to the risk of development of ocular diseases including, but not limited to, Age-related Macular Degeneration (AMD) that is a leading cause of blindness in the United States as well as worldwide. Retinal aging, that contributes to AMD pathogenesis, is cha …
Aging contributes to the risk of development of ocular diseases including, but not limited to, Age-related Macular Degeneration (AMD) that i …
Retinal Degeneration and Alzheimer's Disease: An Evolving Link.
Ashok A, Singh N, Chaudhary S, Bellamkonda V, Kritikos AE, Wise AS, Rana N, McDonald D, Ayyagari R. Ashok A, et al. Int J Mol Sci. 2020 Oct 2;21(19):7290. doi: 10.3390/ijms21197290. Int J Mol Sci. 2020. PMID: 33023198 Free PMC article. Review.
Neuroinflammation and brain iron dyshomeostasis accompany Abeta and p-tau deposits and, together, lead to progressive neuronal death and dementia. The accumulation of Abeta and iron in drusen, the hallmark of AMD, and Abeta and p-tau in retinal ganglion cells (RGC), …
Neuroinflammation and brain iron dyshomeostasis accompany Abeta and p-tau deposits and, together, lead to progressive neuronal death and dem …
Mechanisms of mitochondrial dysfunction and their impact on age-related macular degeneration.
Kaarniranta K, Uusitalo H, Blasiak J, Felszeghy S, Kannan R, Kauppinen A, Salminen A, Sinha D, Ferrington D. Kaarniranta K, et al. Prog Retin Eye Res. 2020 Nov;79:100858. doi: 10.1016/j.preteyeres.2020.100858. Epub 2020 Apr 13. Prog Retin Eye Res. 2020. PMID: 32298788 Free PMC article. Review.
Oxidative stress-induced damage to the retinal pigment epithelium (RPE) is considered to be a key factor in age-related macular degeneration (AMD) pathology. ...There is increasing evidence that proteostasis is disturbed in RPE as evidenced by lysosomal lipofuscin and extr …
Oxidative stress-induced damage to the retinal pigment epithelium (RPE) is considered to be a key factor in age-related macular degen …
RETINAL OPTICAL COHERENCE TOMOGRAPHY IMAGING BIOMARKERS: A Review of the Literature.
Pandya BU, Grinton M, Mandelcorn ED, Felfeli T. Pandya BU, et al. Retina. 2024 Mar 1;44(3):369-380. doi: 10.1097/IAE.0000000000003974. Retina. 2024. PMID: 37903455 Free PMC article. Review.
The age-related macular degeneration group included outer retinal tubulation, multilayered pigment epithelial detachment, prechoroidal cleft, onion sign, double-layer sign, complete outer retinal atrophy, complete retinal pigment epithelium and outer retin
The age-related macular degeneration group included outer retinal tubulation, multilayered pigment epithelial detachment, prechoroida …
Phenotyping and genotyping inherited retinal diseases: Molecular genetics, clinical and imaging features, and therapeutics of macular dystrophies, cone and cone-rod dystrophies, rod-cone dystrophies, Leber congenital amaurosis, and cone dysfunction syndromes.
Georgiou M, Robson AG, Fujinami K, de Guimarães TAC, Fujinami-Yokokawa Y, Daich Varela M, Pontikos N, Kalitzeos A, Mahroo OA, Webster AR, Michaelides M. Georgiou M, et al. Prog Retin Eye Res. 2024 May;100:101244. doi: 10.1016/j.preteyeres.2024.101244. Epub 2024 Jan 24. Prog Retin Eye Res. 2024. PMID: 38278208 Review.
Inherited retinal diseases (IRD) are a leading cause of blindness in the working age population and in children. The scope of this review is to familiarise clinicians and scientists with the current landscape of molecular genetics, clinical phenotype, retinal imagin …
Inherited retinal diseases (IRD) are a leading cause of blindness in the working age population and in children. The scope of this re …
AGE-RELATED MACULAR DEGENERATION.
Gheorghe A, Mahdi L, Musat O. Gheorghe A, et al. Rom J Ophthalmol. 2015 Apr-Jun;59(2):74-7. Rom J Ophthalmol. 2015. PMID: 26978865 Free PMC article. Review.
It is characterized by the appearance of drusen in the macula, accompanied by choroidal neovascularization (CNV) or geographic atrophy....
It is characterized by the appearance of drusen in the macula, accompanied by choroidal neovascularization (CNV) or geographic atroph …
A Linkage between Angiogenesis and Inflammation in Neovascular Age-Related Macular Degeneration.
Heloterä H, Kaarniranta K. Heloterä H, et al. Cells. 2022 Nov 1;11(21):3453. doi: 10.3390/cells11213453. Cells. 2022. PMID: 36359849 Free PMC article. Review.
The progression of AMD is initially characterized by atrophic alterations in the retinal pigment epithelium, as well as the formation of lysosomal lipofuscin and extracellular drusen deposits. ...
The progression of AMD is initially characterized by atrophic alterations in the retinal pigment epithelium, as well as the formation …
322 results