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Current status of beta-thalassemia and its treatment strategies.
Ali S, Mumtaz S, Shakir HA, Khan M, Tahir HM, Mumtaz S, Mughal TA, Hassan A, Kazmi SAR, Sadia, Irfan M, Khan MA. Ali S, et al. Mol Genet Genomic Med. 2021 Dec;9(12):e1788. doi: 10.1002/mgg3.1788. Epub 2021 Nov 5. Mol Genet Genomic Med. 2021. PMID: 34738740 Free PMC article. Review.
Beta-thalassemia is caused by one or more mutations in the beta-globin gene. The absence or reduced amount of beta-globin chains causes ineffective erythropoiesis which leads to anemia. METHODS: Beta-thalassemia has been further divided i
Beta-thalassemia is caused by one or more mutations in the beta-globin gene. The absence or reduced amount of beta
beta-Thalassemia.
Origa R. Origa R. Genet Med. 2017 Jun;19(6):609-619. doi: 10.1038/gim.2016.173. Epub 2016 Nov 3. Genet Med. 2017. PMID: 27811859 Free article. Review.
beta-Thalassemia is caused by reduced (beta(+)) or absent (beta(0)) synthesis of the beta-globin chains of hemoglobin. ...Factors include the inheritance of mild/silent beta-thalassemia mutations, the coinheritance of alpha-
beta-Thalassemia is caused by reduced (beta(+)) or absent (beta(0)) synthesis of the beta-globin chains o
Relationship between genotype and phenotype. Thalassemia intermedia.
Galanello R, Cao A. Galanello R, et al. Ann N Y Acad Sci. 1998 Jun 30;850:325-33. doi: 10.1111/j.1749-6632.1998.tb10489.x. Ann N Y Acad Sci. 1998. PMID: 9668554 Review.
Thalassemia intermedia encompasses a number of clinical conditions ranging in severity from beta-thalassemia carrier state to transfusion-dependent thalassemia major. ...These factors are the presence of a silent or mild beta-thalassem
Thalassemia intermedia encompasses a number of clinical conditions ranging in severity from beta-thalassemia carrier st